Can language models (LMs) self-refine their own responses? This question is increasingly relevant as a wide range of real-world user interactions involve refinement requests. However, prior studies have largely tested LMs' refinement abilities on verifiable tasks such as competition math or symbolic reasoning with simplified scaffolds, whereas users often pose open-ended queries and provide varying degrees of feedback on what they desire. The recent advent of reasoning models that exhibit self-reflection patterns in their chains-of-thought further motivates this question. To analyze this, we introduce RefineBench, a benchmark of 1,000 challenging problems across 11 domains paired with a checklist-based evaluation framework. We evaluate two refinement modes: (1) guided refinement, where an LM is provided natural language feedback, and (2) self-refinement, where LMs attempt to improve without guidance. In the self-refinement setting, even frontier LMs such as Gemini 2.5 Pro and GPT-5 achieve modest baseline scores of 31.3% and 29.1%, respectively, and most models fail to consistently improve across iterations (e.g., Gemini-2.5-Pro gains only +1.8%, while DeepSeek-R1 declines by -0.1%). By contrast, in guided refinement, both proprietary LMs and large open-weight LMs (>70B) can leverage targeted feedback to refine responses to near-perfect levels within five turns. These findings suggest that frontier LMs require breakthroughs to self-refine their incorrect responses, and that RefineBench provides a valuable testbed for tracking progress.

This study investigates the effectiveness and efficiency of two variants of the XGBoost regression model, the full-capacity and lightweight (tiny) versions, for predicting the concentrations of carbon monoxide (CO) and nitrogen dioxide (NO2). Using the AirQualityUCI dataset collected over one year in an urban environment, we conducted a comprehensive evaluation based on widely accepted metrics, including Mean Absolute Error (MAE), Root Mean Square Error (RMSE), Mean Bias Error (MBE), and the coefficient of determination (R2). In addition, we assessed resource-oriented metrics such as inference time, model size, and peak RAM usage. The full XGBoost model achieved superior predictive accuracy for both pollutants, while the tiny model, though slightly less precise, offered substantial computational benefits with significantly reduced inference time and model storage requirements. These results demonstrate the feasibility of deploying simplified models in resource-constrained environments without compromising predictive quality. This makes the tiny XGBoost model suitable for real-time air-quality monitoring in IoT and embedded applications.

Traditional rigid underwater vehicles pose risks to delicate marine ecosystems due to high-speed propellers and rigid hulls. This paper presents BactoBot, a low-cost, soft underwater robot designed for safe and gentle marine exploration. Inspired by the efficient flagellar propulsion of bacteria, BactoBot features 12 flexible, silicone-based arms arranged on a dodecahedral frame. Unlike high-cost research platforms, this prototype was fabricated using accessible DIY methods, including food-grade silicone molding, FDM 3D printing, and off-the-shelf DC motors. A novel multi-stage waterproofing protocol was developed to seal rotating shafts using a grease-filled chamber system, ensuring reliability at low cost. The robot was successfully tested in a controlled aquatic environment, demonstrating stable forward propulsion and turning maneuvers. With a total fabrication cost of approximately $355 USD, this project validates the feasibility of democratizing soft robotics for marine science in resource-constrained settings.

Yttrium plays a critical role in everything from aircraft engines to semiconductors. China controls the vast majority of the market--and that's not changing anytime soon. The alarm hasn't yet reached the general public, but tension is beginning to build in the corridors of the aerospace industry, in microchip laboratories, and in government offices. For months, an element almost invisible to the world--yttrium--has become the silent center of a new global dispute. Supplies are thinning, prices are skyrocketing, deliveries are stalling.

Efficient nutrient management is critical for crop growth and sustainable resource consumption (e.g., nitrogen, energy). Current approaches require lengthy analyses, preventing real-time optimization; similarly, imaging facilitates rapid phenotyping but can be computationally intensive, preventing deployment under resource constraints. This study proposes a flexible, tiered pipeline for anomaly detection and status estimation (fresh weight, dry mass, and tissue nutrients), including a comprehensive energy analysis of approaches that span the efficiency-accuracy spectrum. Using a nutrient depletion experiment with three treatments (T1-100%, T2-50%, and T3-25% fertilizer strength) and multispectral imaging (MSI), we developed a hierarchical pipeline using an autoencoder (AE) for early warning. Further, we compared two status estimation modules of different complexity for more detailed analysis: vegetation index (VI) features with machine learning (Random Forest, RF) and raw whole-image deep learning (Vision Transformer, ViT). Results demonstrated high-efficiency anomaly detection (73% net detection of T3 samples 9 days after transplanting) at substantially lower energy than embodied energy in wasted nitrogen. The state estimation modules show trade-offs, with ViT outperforming RF on phosphorus and calcium estimation (R2 0.61 vs. 0.58, 0.48 vs. 0.35) at higher energy cost. With our modular pipeline, this work opens opportunities for edge diagnostics and practical opportunities for agricultural sustainability.

Accurate and efficient seismic response prediction is essential for the design of resilient structures. While the Finite Element Method (FEM) remains the standard for nonlinear seismic analysis, its high computational demands limit its scalability and real time applicability. Recent developments in deep learning, particularly Convolutional Neural Networks (CNNs), Recurrent Neural Networks (RNNs), and Long Short Term Memory (LSTM) models, have shown promise in reducing the computational cost of nonlinear seismic analysis of structures. However, these data driven models often struggle to generalize and capture the underlying physics, leading to reduced reliability. We propose a novel Physics Informed U Net LSTM framework that integrates physical laws with deep learning to enhance both accuracy and efficiency. By embedding domain specific constraints into the learning process, the proposed model achieves improved predictive performance over conventional Machine Learning architectures. This hybrid approach bridges the gap between purely data driven methods and physics based modeling, offering a robust and computationally efficient alternative for seismic response prediction of structures.

The Trump Administration's Data Center Push Could Open the Door for New Forever Chemicals The EPA is prioritizing review of new chemicals to be used in data centers. Experts say this could lead to the fast approval of new types of forever chemicals--with limited oversight. In recent months, the Trump administration has opened a deregulatory floodgate in the name of building more data centers. Among other things, this has involved ordering rollbacks of clean water regulations and opening up public lands to coal mining. Now, it's turning its eye to chemical regulation with a new policy that could, experts say, potentially fast-track the approval of new chemicals for use in the US--including new types of forever chemicals--with limited oversight. In September, the EPA announced it would be prioritizing the regulatory review of new chemicals used in data centers or related projects.

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The discovery of high-performance photosensitizers has long been hindered by the time-consuming and resource-intensive nature of traditional trial-and-error approaches. Here, we present \textbf{A}I-\textbf{A}ccelerated \textbf{P}hoto\textbf{S}ensitizer \textbf{I}nnovation (AAPSI), a closed-loop workflow that integrates expert knowledge, scaffold-based molecule generation, and Bayesian optimization to accelerate the design of novel photosensitizers. The scaffold-driven generation in AAPSI ensures structural novelty and synthetic feasibility, while the iterative AI-experiment loop accelerates the discovery of novel photosensitizers. AAPSI leverages a curated database of 102,534 photosensitizer-solvent pairs and generate 6,148 synthetically accessible candidates. These candidates are screened via graph transformers trained to predict singlet oxygen quantum yield ($ϕ_Δ$) and absorption maxima ($λ_{max}$), following experimental validation. This work generates several novel candidates for photodynamic therapy (PDT), among which the hypocrellin-based candidate HB4Ph exhibits exceptional performance at the Pareto frontier of high quantum yield of singlet oxygen and long absorption maxima among current photosensitizers ($ϕ_Δ$=0.85, $λ_{max}$=650nm).

Generative Flow Networks, or GFlowNets, offer a promising framework for molecular design, but their internal decision policies remain opaque. This limits adoption in drug discovery, where chemists require clear and interpretable rationales for proposed structures. We present an interpretability framework for SynFlowNet, a GFlowNet trained on documented chemical reactions and purchasable starting materials that generates both molecules and the synthetic routes that produce them. Our approach integrates three complementary components. Gradient based saliency combined with counterfactual perturbations identifies which atomic environments influence reward and how structural edits change molecular outcomes. Sparse autoencoders reveal axis aligned latent factors that correspond to physicochemical properties such as polarity, lipophilicity, and molecular size. Motif probes show that functional groups including aromatic rings and halogens are explicitly encoded and linearly decodable from the internal embeddings. Together, these results expose the chemical logic inside SynFlowNet and provide actionable and mechanistic insight that supports transparent and controllable molecular design.