FDA
Digital health helping cancer diagnosis - Pharmaphorum
The FDA has been championing digital health of late with wide-ranging guidance that derives from the 21st Century Cures Act. This legislation acknowledges the potential that digital health has to make a difference in patient care, potentially leading to more precise therapies. Several developments this week show that the regulator is right to be excited about its potential. Some of the most exciting advances have come in the field of cancer โ medical devices firm Angle has produced a new analysis showing that its liquid biopsy device Parsortix could be used instead of conventional tissue biopsies. Parsortix works by monitoring a patient's bloodstream for circulating cancer cells and the University of Southern California research adds to the body of evidence showing that liquid biopsies could replace invasive and unpleasant tissue biopsies in the future.
FDA Clears First Medical Device Accessory for Apple Watch
The device, made by AliveCor, pairs the ability to take a personal 30 second electrocardiogram (EKG) with a feature that uses artificial intelligence to continuously evaluate the correlation between heart and physical activity. When the device, known as KardiaBand, detects that a user's heart rate and activity are out of sync, it prompts the user to capture an EKG by touching the band. The results display instantly on the watch face. The device is designed to capture information that can help doctors help manage atrial fibrillation, the most common heart arrhythmia that is a leading cause of stroke and affects more than 30 million people worldwide. The device costs $199 and requires a subscription to the company's premium service for $99 a year.
FDA clears first EKG band for the Apple Watch
AliveCor's KardiaBand, a device that detect dangerous heart rhythms, has become the first Apple Watch accessory cleared for medical use by the FDA, the company announced. It can capture your EKG in 30 seconds, then detect problems like atrial fibrillation, a type of heart arrhythmia. In addition, the company launched a new version of the band today in the US with a feature called SmartRhythm. That uses Apple's built-in heart rate sensor and AI algorithms to warn you if your heart rate is elevated when you're not exercising or doing strenuous activities. FDA clearance means that AliveCor can sell and market it as a medical device, but users don't need doctor approval to use it.
EKG-Reading Kardia Band Is First Apple Watch Accessory To Get FDA Clearance
Kardia Band attaches to the Apple Watch like any other replaceable watch band. The user rests a finger on the sensor pad embedded in the band, allowing an EKG reading to be taken. The Kardia Band transmits its EKG reading to the Apple Watch (via a high-pitch audio signal) where it's displayed in real time as a moving waveform. When the 30-second EKG is finished, the user can view it on their phone or easily send the results as a PDF to their physician. Doctors can diagnose hundreds of diseases using EKG data, but AliveCor is cleared by the FDA only to record the EKG and to advise a user that the reading is normal, or possibly indicative of atrial fibrillation.
Snorkel: Rapid Training Data Creation with Weak Supervision
Ratner, Alexander, Bach, Stephen H., Ehrenberg, Henry, Fries, Jason, Wu, Sen, Rรฉ, Christopher
Labeling training data is increasingly the largest bottleneck in deploying machine learning systems. We present Snorkel, a first-of-its-kind system that enables users to train state-of-the-art models without hand labeling any training data. Instead, users write labeling functions that express arbitrary heuristics, which can have unknown accuracies and correlations. Snorkel denoises their outputs without access to ground truth by incorporating the first end-to-end implementation of our recently proposed machine learning paradigm, data programming. We present a flexible interface layer for writing labeling functions based on our experience over the past year collaborating with companies, agencies, and research labs. In a user study, subject matter experts build models 2.8x faster and increase predictive performance an average 45.5% versus seven hours of hand labeling. We study the modeling tradeoffs in this new setting and propose an optimizer for automating tradeoff decisions that gives up to 1.8x speedup per pipeline execution. In two collaborations, with the U.S. Department of Veterans Affairs and the U.S. Food and Drug Administration, and on four open-source text and image data sets representative of other deployments, Snorkel provides 132% average improvements to predictive performance over prior heuristic approaches and comes within an average 3.60% of the predictive performance of large hand-curated training sets.
Artificial Intelligence Human Intelligence Our Future
When I was a scrawny little chap, shortest in my high school class, I always wanted a super power. Wanted doesn't capture the feeling. I would have given a limb for a super power. I read a lot of books back then (and now) and landed on a super power that had something to do with the brain. I eventually landed on Prof. Xavier of the X-Men.
New blood test developed to diagnose ovarian cancer
Investigators from Brigham and Women's Hospital and Dana-Farber Cancer Institute are leveraging the power of artificial intelligence to develop a new technique to detect ovarian cancer early and accurately. The team has identified a network of circulating microRNAs - small, non-coding pieces of genetic material - that are associated with risk of ovarian cancer and can be detected from a blood sample. Their findings are published online in eLife. Most women are diagnosed with ovarian cancer when the disease is at an advanced stage, at which point only about a quarter of patients will survive for at least five years. But for women whose cancer is serendipitously picked up at an early stage, survival rates are much higher.
10 Mobile Health Startups Making You Feel Better - Nanalyze
In 1983, the IBM PC XT debuted with 128K of RAM and a 10MB hard disk. In that same year, the first mobile phone debuted weighing about 2.5 pounds and with a $4,000 price tag. Fast forward to today and the average person unlocks their smartphone 76-80 times a day and relies on it for every aspect of their lives. These amazing pieces of hardware are millions of times more capable than all of NASA's computing power in the 1960s. Now that we have a supercomputer that never leaves people's sides, maybe it's time that we do some more innovation and see how that device can be used for "mobile health".
Darpa reveals device that increases learning by 40%
The idea of a headband you can wear to make you smarter may sound like a device from the latest science fiction blockbuster. But experts have revealed such a device in reality โ and claim it could increase learning by 40 per cent. And it may not be long before you can get your hands on one, with the designers predicting its use will be common in just five to ten years. The idea of a headband you can wear to make you smarter may sound like a device from the latest science fiction blockbuster. But experts have revealed such a device in reality โ and claim it could increase learning by 40 per cent.
AI-powered pathology is transforming cancer care
In May, Sundar Pichai, CEO of Google, discussed AI applications for digital pathology in his keynote speech to an audience of millions at Google's annual I/O event. Five weeks earlier, the FDA announced it had approved the first whole slide imaging system for primary diagnostic use in pathology. Both events point to the future of pathology and laboratory medicine: Software will soon dominate. Over the past 20 years, software has taken over the world. Retail was dominated by Amazon, Netflix put Blockbuster out of business, and Uber used software to take over the taxi industry.