This paper introduces a testbed to study distributed sensing problems of Unmanned Aerial Vehicles (UAVs) exhibiting swarm intelligence. Several Smart City applications, such as transport and disaster response, require efficient collection of sensor data by a swarm of intelligent and cooperative UAVs. This often proves to be too complex and costly to study systematically and rigorously without compromising scale, realism and external validity. With the proposed testbed, this paper sets a stepping stone to emulate, within small laboratory spaces, large sensing areas of interest originated from empirical data and simulation models. Over this sensing map, a swarm of low-cost drones can fly allowing the study of a large spectrum of problems such as energy consumption, charging control, navigation and collision avoidance. The applicability of a decentralized multi-agent collective learning algorithm (EPOS) for UAV swarm intelligence along with the assessment of power consumption measurements provide a proof-of-concept and validate the accuracy of the proposed testbed.

We propose an end-to-end framework based on a Graph Neural Network (GNN) to balance the power flows in energy grids. The balancing is framed as a supervised vertex regression task, where the GNN is trained to predict the current and power injections at each grid branch that yield a power flow balance. By representing the power grid as a line graph with branches as vertices, we can train a GNN that is accurate and robust to changes in topology. In addition, by using specialized GNN layers, we are able to build a very deep architecture that accounts for large neighborhoods on the graph, while implementing only localized operations. We perform three different experiments to evaluate: i) the benefits of using localized rather than global operations and the tendency of deep GNN models to oversmooth the quantities on the nodes; ii) the resilience to perturbations in the graph topology; and iii) the capability to train the model simultaneously on multiple grid topologies and the consequential improvement in generalization to new, unseen grids. The proposed framework is efficient and, compared to other solvers based on deep learning, is robust to perturbations not only to the physical quantities on the grid components, but also to the topology.

Today Insilico Medicine announced the completion of a second closing of its Series D round, led by Prosperity7 Ventures, the diversified growth fund of Saudi Aramco Ventures, bringing the total Series D financing to $95 million. Other global investors with expertise in the biopharmaceutical and life sciences sectors also participated. The financing brought in Prosperity7 as a new investor, alongside current investors in the Series D round, including a large, diversified asset management firm on the US West Coast, B Capital Group, Warburg Pincus, BHR Partners, Qiming Venture Partners, Deerfield, Pavilion Capital, BOLD Capital Partners, and WS Investment Company. Insilico's founder and CEO, Alex Zhavoronkov, PhD, also invested in the Series D round. Insilico Medicine plans to grow its presence in Saudi Arabia, building on the recent investment from Prosperity7.

Role requiring'No experience data provided' months of experience in Houston About VLink: Started in 2006 and headquartered in Connecticut, VLink is one of the fastest-growing digital technology services and consulting companies. Since its inception, our innovative team members have been solving the most complex business, and IT challenges of our global clients. Client is looking for a Data Architect who is primarily an individual contributor but can be responsible for a small team. Main scope of work is to provide solution architecture development, consultancy and assurance to projects, making sure applications are well designed and conform to client standards and reference/segment architectures. Translates the guidelines and standards into practice and solves common technical challenges and provides technical recommendations which have a perceptible impact on local business performance; actively drives the identification, development and implementation of new technologies and opportunities to optimise technology/IT systems. May represent the Company externally as a subject matter expert with suppliers, customers and external agencies. Empowered to make decisions on solutions within guidelines. Applies TOE standards and raises step-outs if needed. Understands the IT Strategic Roadmap and applies within the context of their organisational assignment.

Exact inference in Bayesian networks is intractable and has an exponential dependence on the size of the largest clique in the corresponding clique tree (CT), necessitating approximations. Factor based methods to bound clique sizes are more accurate than structure based methods, but expensive since they involve inference of beliefs in a large number of candidate structure or region graphs. We propose an alternative approach for approximate inference based on an incremental build-infer-approximate (IBIA) paradigm, which converts the Bayesian network into a data structure containing a sequence of linked clique tree forests (SLCTF), with clique sizes bounded by a user-specified value. In the incremental build stage of this approach, CTFs are constructed incrementally by adding variables to the CTFs as long as clique sizes are within the specified bound. Once the clique size constraint is reached, the CTs in the CTF are calibrated in the infer stage of IBIA. The resulting clique beliefs are used in the approximate phase to get an approximate CTF with reduced clique sizes. The approximate CTF forms the starting point for the next CTF in the sequence. These steps are repeated until all variables are added to a CTF in the sequence. We prove that our algorithm for incremental construction of clique trees always generates a valid CT and our approximation technique preserves the joint beliefs of the variables within a clique. Based on this, we show that the SLCTF data structure can be used for efficient approximate inference of partition function and prior and posterior marginals. More than 500 benchmarks were used to test the method and the results show a significant reduction in error when compared to other approximate methods, with competitive runtimes.

A deep learning (DL) closure model for large-eddy simulation (LES) is developed and evaluated for incompressible flows around a rectangular cylinder at moderate Reynolds numbers. Near-wall flow simulation remains a central challenge in aerodynamic modeling: RANS predictions of separated flows are often inaccurate, while LES can require prohibitively small near-wall mesh sizes. The DL-LES model is trained using adjoint PDE optimization methods to match, as closely as possible, direct numerical simulation (DNS) data. It is then evaluated out-of-sample (i.e., for new aspect ratios and Reynolds numbers not included in the training data) and compared against a standard LES model (the dynamic Smagorinsky model). The DL-LES model outperforms dynamic Smagorinsky and is able to achieve accurate LES predictions on a relatively coarse mesh (downsampled from the DNS grid by a factor of four in each Cartesian direction). We study the accuracy of the DL-LES model for predicting the drag coefficient, mean flow, and Reynolds stress. A crucial challenge is that the LES quantities of interest are the steady-state flow statistics; for example, the time-averaged mean velocity $\bar{u}(x) = \displaystyle \lim_{t \rightarrow \infty} \frac{1}{t} \int_0^t u(s,x) ds$. Calculating the steady-state flow statistics therefore requires simulating the DL-LES equations over a large number of flow times through the domain; it is a non-trivial question whether an unsteady partial differential equation model whose functional form is defined by a deep neural network can remain stable and accurate on $t \in [0, \infty)$. Our results demonstrate that the DL-LES model is accurate and stable over large physical time spans, enabling the estimation of the steady-state statistics for the velocity, fluctuations, and drag coefficient of turbulent flows around bluff bodies relevant to aerodynamic applications.

We propose a novel model selection algorithm based on a penalized maximum likelihood estimator (PMLE) for functional hidden dynamic geostatistical models (f-HDGM). These models employ a classic mixed-effect regression structure with embedded spatiotemporal dynamics to model georeferenced data observed in a functional domain. Thus, the parameters of interest are functions across this domain. The algorithm simultaneously selects the relevant spline basis functions and regressors that are used to model the fixed-effects relationship between the response variable and the covariates. In this way, it automatically shrinks to zero irrelevant parts of the functional coefficients or the entire effect of irrelevant regressors. The algorithm is based on iterative optimisation and uses an adaptive least absolute shrinkage and selector operator (LASSO) penalty function, wherein the weights are obtained by the unpenalised f-HDGM maximum-likelihood estimators. The computational burden of maximisation is drastically reduced by a local quadratic approximation of the likelihood. Through a Monte Carlo simulation study, we analysed the performance of the algorithm under different scenarios, including strong correlations among the regressors. We showed that the penalised estimator outperformed the unpenalised estimator in all the cases we considered. We applied the algorithm to a real case study in which the recording of the hourly nitrogen dioxide concentrations in the Lombardy region in Italy was modelled as a functional process with several weather and land cover covariates.

In this work, we optimize the 3D trajectory of an unmanned aerial vehicle (UAV)-based portable access point (PAP) that provides wireless services to a set of ground nodes (GNs). Moreover, as per the Peukert effect, we consider pragmatic non-linear battery discharge for the battery of the UAV. Thus, we formulate the problem in a novel manner that represents the maximization of a fairness-based energy efficiency metric and is named fair energy efficiency (FEE). The FEE metric defines a system that lays importance on both the per-user service fairness and the energy efficiency of the PAP. The formulated problem takes the form of a non-convex problem with non-tractable constraints. To obtain a solution, we represent the problem as a Markov Decision Process (MDP) with continuous state and action spaces. Considering the complexity of the solution space, we use the twin delayed deep deterministic policy gradient (TD3) actor-critic deep reinforcement learning (DRL) framework to learn a policy that maximizes the FEE of the system. We perform two types of RL training to exhibit the effectiveness of our approach: the first (offline) approach keeps the positions of the GNs the same throughout the training phase; the second approach generalizes the learned policy to any arrangement of GNs by changing the positions of GNs after each training episode. Numerical evaluations show that neglecting the Peukert effect overestimates the air-time of the PAP and can be addressed by optimally selecting the PAP's flying speed. Moreover, the user fairness, energy efficiency, and hence the FEE value of the system can be improved by efficiently moving the PAP above the GNs. As such, we notice massive FEE improvements over baseline scenarios of up to 88.31%, 272.34%, and 318.13% for suburban, urban, and dense urban environments, respectively.

Conic optimization has recently emerged as a powerful tool for designing tractable and guaranteed algorithms for non-convex polynomial optimization problems. On the one hand, tractability is crucial for efficiently solving large-scale problems and, on the other hand, strong bounds are needed to ensure high quality solutions. In this research, we investigate the strengthening of RLT relaxations of polynomial optimization problems through the addition of nine different types of constraints that are based on linear, second-order cone, and semidefinite programming to solve to optimality the instances of well established test sets of polynomial optimization problems. We describe how to design these conic constraints and their performance with respect to each other and with respect to the standard RLT relaxations. Our first finding is that the different variants of nonlinear constraints (second-order cone and semidefinite) are the best performing ones in around $50\%$ of the instances. Additionally, we present a machine learning approach to decide on the most suitable constraints to add for a given instance. The computational results show that the machine learning approach significantly outperforms each and every one of the nine individual approaches.

Despite the vast empirical success of neural networks, theoretical understanding of the training procedures remains limited, especially in providing performance guarantees of testing performance due to the non-convex nature of the optimization problem. The current paper investigates an alternative approach of neural network training by reducing to another problem with convex structure -- to solve a monotone variational inequality (MVI) -- inspired by a recent work of (Juditsky & Nemirovsky, 2019). The solution to MVI can be found by computationally efficient procedures, and importantly, this leads to performance guarantee of $\ell_2$ and $\ell_{\infty}$ bounds on model recovery and prediction accuracy under the theoretical setting of training a single-layer linear neural network. In addition, we study the use of MVI for training multi-layer neural networks and propose a practical algorithm called \textit{stochastic variational inequality} (SVI), and demonstrate its applicability in training fully-connected neural networks and graph neural networks (GNN) (SVI is completely general and can be used to train other types of neural networks). We demonstrate the competitive or better performance of SVI compared to widely-used stochastic gradient descent methods on both synthetic and real network data prediction tasks regarding various performance metrics, especially in the improved efficiency in the early stage of training.