Recent advances have significantly improved our understanding of the generalization performance of gradient descent (GD) methods in deep neural networks. A natural and fundamental question is whether GD can achieve generalization rates comparable to the minimax optimal rates established in the kernel setting. Existing results either yield suboptimal rates of O(1/ n), or focus on networks with smooth activation functions, incurring exponential dependence on network depth L. In this work, we establish optimal generalization rates for GD with deep ReLU networks by carefully trading off optimization and generalization errors, achieving only polynomial dependence on depth. Specifically, under the assumption that the data are NTK separable from the margin γ, we prove an excess risk rate of eO(L6/(nγ2)), which aligns with the optimal SVM-type rate eO(1/(nγ2)) up to depth-dependent factors. A key technical contribution is our novel control of activation patterns near a reference model, enabling a sharper Rademacher complexity bound for deep ReLU networks trained with gradient descent.

Data integration approaches are increasingly used to enhance the efficiency and generalizability of studies. However, a key limitation of these methods is the assumption that outcome measures are identical across datasets - an assumption that often does not hold in practice. Consider the following opioid use disorder (OUD) studies: the XBOT trial and the POAT study, both evaluating the effect of medications for OUD on withdrawal symptom severity (not the primary outcome of either trial). While XBOT measures withdrawal severity using the subjective opiate withdrawal scale, POAT uses the clinical opiate withdrawal scale. We analyze this realistic yet challenging setting where outcome measures differ across studies and where neither study records both types of outcomes. Our paper studies whether and when integrating studies with disparate outcome measures leads to efficiency gains.

Large Language Models (LLMs) continue to exhibit vulnerabilities despite deliberate safety alignment efforts, posing significant risks to users and society. To safeguard against the risk of policy-violating content, system-level moderation via external guard models--designed to monitor LLM inputs and outputs and block potentially harmful content--has emerged as a prevalent mitigation strategy. Existing approaches of training guard models rely heavily on extensive human curated datasets and struggle with out-of-distribution threats, such as emerging harmful categories or jailbreak attacks. To address these limitations, we propose RSafe, an adaptive reasoning-based safeguard that conducts guided safety reasoning to provide robust protection within the scope of specified safety policies. RSafe operates in two stages: (1) guided reasoning, where it analyzes safety risks of input content through policy-guided step-by-step reasoning, and (2) reinforced alignment, where rule-based RL optimizes its reasoning paths to align with accurate safety prediction.

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Large language models (LLMs), despite their impressive performance across a wide range of tasks, often struggle to balance two competing objectives in openended text generation: fostering diversity and creativity while preserving logical coherence. Existing truncated sampling techniques, including temperature scaling, top-p (nucleus) sampling, and min-p sampling, aim to manage this trade-off.

This paper addresses the problem of learning avoidance behavior within the context of offline imitation learning. In contrast to conventional methodologies that prioritize the replication of expert or near-expert demonstrations, our work investigates a setting where expert (or desirable) data is absent, and the objective is to learn to eschew undesirable actions by leveraging demonstrations of such behavior (i.e., learning from negative examples). To address this challenge, we propose a novel training objective grounded in the maximum entropy principle. We further characterize the fundamental properties of this objective function, reformulating the learning process as a cooperative inverse Q-learning task. Moreover, we introduce an efficient strategy for the integration of unlabeled data (i.e., data of indeterminate quality) to facilitate unbiased and practical offline training. The efficacy of our method is evaluated across standard benchmark environments, where it consistently outperforms state-of-the-art baselines.

Designing protein sequences that fold into a target 3D structure--known as protein inverse folding--is a fundamental challenge in protein engineering. While recent deep learning methods have achieved impressive performance by recovering native sequences, they often overlook the one-to-many nature of the problem: multiple diverse sequences can fold into the same structure.

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Continual learning is often motivated by the idea, known as the big world hypothesis, that "the world is bigger" than the agent. Recent problem formulations capture this idea by explicitly constraining an agent relative to the environment. These constraints lead to solutions in which the agent continually adapts to best use its limited capacity, rather than converging to a fixed solution. However, explicit constraints can be ad hoc, difficult to incorporate, and may limit the effectiveness of scaling up the agent's capacity. In this paper, we characterize a problem setting in which an agent, regardless of its capacity, is constrained by being embedded in the environment.

We present a Directional Consistency (DC)-driven Adaptive Density Control (ADC) for 3DGaussian Splatting (DC4GS). Whereas the conventional ADC bases its primiti the DC ve of splitting the gradients on the magnitudes into ADC, and of positional realize it gradients, through the we angular further incorporate coherence of the gradients.