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He Won the Nobel Prize for Protein Design. Now He Uses AI to Create Molecules Not Found in Nature
David Baker spoke with WIRED en Español about where biological design is headed next and the great potential and risks of taking biology outside the bounds of the natural world. David Baker, a pioneer of protein design, is using AI to go where nature hasn't. The natural world as we know it represents only a fraction of what might exist. Based on this idea, AI BioDesign was born: a scientific project that combines artificial intelligence and large-scale laboratory experiments to design and test new molecules and biological functions that are not found in nature but are physically and chemically possible. In doing so, the researchers are aiming to create databases, models, and tools that could serve as "seeds" for developing the medicines and technologies of the future.
Has Queen Nefertiti finally been found? New scans provide fresh evidence for a hidden chamber beyond Tutankhamun's tomb that could hold the remains of his long-lost stepmother
You're viewing the US edition You can switch to the UK or AU homepage at any time using this menu. Lindsay Clancy holdout juror breaks silence: Why he voted GUILTY... and how the others tried to sway him REBECCA ENGLISH: William is'furious'... and as for the King, I can't even begin to convey his anger: Everything I'm hearing from inside the Palace after Earl Spencer's astonishing book claims Yet again, Harry and Meghan have humiliated themselves in a mess of their own making. Inside Kim Zolciak and husband Kroy Biermann's house of horrors: As son KJ, 15, faces sex abuse allegations involving classmate, watch the shock bodycam footage from before teenager's arrest and read the devastating claims of home violence'Kissing virus' infecting 90% of Americans linked to worse symptoms of devastating neurological disorder Read the book so raw and revealing it has started a war of words with the King. In searing detail, EARL SPENCER recalls Charles's behaviour in the hours and days after Diana died Which midterm races should YOU be watching? Enter your zip code in Daily Mail's exclusive election calculator Outcry as cause of death for teen who vanished during trip to'Sex Rock' is revealed Pentagon insiders unleash on Pete Hegseth's'meddling' wife: Whistleblowers reveal her humiliating nickname among staff... how she keeps husband on'extremely tight leash'... and eyebrow-raising behavior in government meetings Lawmakers freak out at Melania Trump's'creepy' AI robots plan for kids as panic grips nation Real reason'insecure' Amanda Seyfried and Thomas Sadoski's marriage collapsed: Insiders reveal perfect storm of his secret struggle and her'palpable' personal issue that ruined everything College volleyball star dead at 20 just weeks after being diagnosed with'rare disorder' as family shares heartbreaking tribute Woman behind the wheel of SUV that slammed into LA bus before NBC chopper crash was'impaired by drugs' as prior convictions are revealed Ole Miss introduces strict new rule for LSU fans attending Lane Kiffin's return with threat to kick them out of stadium Sickly man loses $450k home over $977 in fees... then HOA snatched the property back for a pittance Julia Stiles calls out'diva' Andy Cohen on DWTS after he labeled her'not the greatest dancer' My husband signed me up to a swingers site without my knowledge - then coerced me into sleeping with 15 men.
Move faster to solve climate challenges, Prince William says
The Prince of Wales has warned that the world needs to move faster to solve the biggest climate challenges. Speaking exclusively to the BBC, Prince William called for a greater sense of urgency around ways to repair the planet. We're not moving fast enough, William said. We need more businesses, investors and leaders to step up, back what works and help bring these solutions to scale. His warning came as this year's nominees for the Earthshot Prize, the global environmental award he launched six years ago, were unveiled.
Now that's what you call mind-blowing! The human brain is TWO separate organs, scientists reveal
You're viewing the US edition You can switch to the UK or AU homepage at any time using this menu. Lindsay Clancy holdout juror breaks silence: Why he voted GUILTY... and how the others tried to sway him REBECCA ENGLISH: William is'furious'... and as for the King, I can't even begin to convey his anger: Everything I'm hearing from inside the Palace after Earl Spencer's astonishing book claims Yet again, Harry and Meghan have humiliated themselves in a mess of their own making. Inside Kim Zolciak and husband Kroy Biermann's house of horrors: As son KJ, 15, faces sex abuse allegations involving classmate, watch the shock bodycam footage from before teenager's arrest and read the devastating claims of home violence'Kissing virus' infecting 90% of Americans linked to worse symptoms of devastating neurological disorder Read the book so raw and revealing it has started a war of words with the King. In searing detail, EARL SPENCER recalls Charles's behaviour in the hours and days after Diana died Which midterm races should YOU be watching? Enter your zip code in Daily Mail's exclusive election calculator Outcry as cause of death for teen who vanished during trip to'Sex Rock' is revealed Pentagon insiders unleash on Pete Hegseth's'meddling' wife: Whistleblowers reveal her humiliating nickname among staff... how she keeps husband on'extremely tight leash'... and eyebrow-raising behavior in government meetings Lawmakers freak out at Melania Trump's'creepy' AI robots plan for kids as panic grips nation Real reason'insecure' Amanda Seyfried and Thomas Sadoski's marriage collapsed: Insiders reveal perfect storm of his secret struggle and her'palpable' personal issue that ruined everything College volleyball star dead at 20 just weeks after being diagnosed with'rare disorder' as family shares heartbreaking tribute Woman behind the wheel of SUV that slammed into LA bus before NBC chopper crash was'impaired by drugs' as prior convictions are revealed Ole Miss introduces strict new rule for LSU fans attending Lane Kiffin's return with threat to kick them out of stadium Sickly man loses $450k home over $977 in fees... then HOA snatched the property back for a pittance Julia Stiles calls out'diva' Andy Cohen on DWTS after he labeled her'not the greatest dancer' My husband signed me up to a swingers site without my knowledge - then coerced me into sleeping with 15 men.
iPhone 18 Pro goes on sale around the world: Huge queues form outside Apple Stores in Kuala Lumpur, Sydney and Singapore - while scalpers set their sights on shoppers in Hangzhou
You're viewing the US edition You can switch to the UK or AU homepage at any time using this menu. Lindsay Clancy holdout juror breaks silence: Why he voted GUILTY... and how the others tried to sway him REBECCA ENGLISH: William is'furious'... and as for the King, I can't even begin to convey his anger: Everything I'm hearing from inside the Palace after Earl Spencer's astonishing book claims Yet again, Harry and Meghan have humiliated themselves in a mess of their own making. Inside Kim Zolciak and husband Kroy Biermann's house of horrors: As son KJ, 15, faces sex abuse allegations involving classmate, watch the shock bodycam footage from before teenager's arrest and read the devastating claims of home violence'Kissing virus' infecting 90% of Americans linked to worse symptoms of devastating neurological disorder Read the book so raw and revealing it has started a war of words with the King. In searing detail, EARL SPENCER recalls Charles's behaviour in the hours and days after Diana died Which midterm races should YOU be watching? Enter your zip code in Daily Mail's exclusive election calculator Outcry as cause of death for teen who vanished during trip to'Sex Rock' is revealed Pentagon insiders unleash on Pete Hegseth's'meddling' wife: Whistleblowers reveal her humiliating nickname among staff... how she keeps husband on'extremely tight leash'... and eyebrow-raising behavior in government meetings Lawmakers freak out at Melania Trump's'creepy' AI robots plan for kids as panic grips nation Real reason'insecure' Amanda Seyfried and Thomas Sadoski's marriage collapsed: Insiders reveal perfect storm of his secret struggle and her'palpable' personal issue that ruined everything College volleyball star dead at 20 just weeks after being diagnosed with'rare disorder' as family shares heartbreaking tribute Woman behind the wheel of SUV that slammed into LA bus before NBC chopper crash was'impaired by drugs' as prior convictions are revealed Ole Miss introduces strict new rule for LSU fans attending Lane Kiffin's return with threat to kick them out of stadium Sickly man loses $450k home over $977 in fees... then HOA snatched the property back for a pittance Julia Stiles calls out'diva' Andy Cohen on DWTS after he labeled her'not the greatest dancer' My husband signed me up to a swingers site without my knowledge - then coerced me into sleeping with 15 men.
Could AI really end humanity? Post your questions for our tech reporters now
After a week of alarming warnings about the technology's potential to destroy the world as we know it, our expert tech reporters will take your questions on the reality of the AI threat. The last week or so has seen disturbing claims about the capacity of superintelligent AI to destroy the planet . It has also seen warnings coming from figures within the industry itself, including Anthropic's report that criminals, state-sponsored groups, spyware vendors, scientists and propagandists have attempted to use its models to "design missiles and bombs, create deadly pathogens and surveil dissidents" and Elon Musk's claim it could be " more dangerous than nukes ". Our reporting team has been trying to make sense of the scale of these claims. Is the great AI freakout justified?
Revealed: The popular children's yoghurts that contain dangerous amounts of sugar - with Nestle's Smarties Vanilla Split Pot at the top of the list
You're viewing the US edition You can switch to the UK or AU homepage at any time using this menu. Lindsay Clancy holdout juror breaks silence: Why he voted GUILTY... and how the others tried to sway him REBECCA ENGLISH: William is'furious'... and as for the King, I can't even begin to convey his anger: Everything I'm hearing from inside the Palace after Earl Spencer's astonishing book claims Yet again, Harry and Meghan have humiliated themselves in a mess of their own making. Inside Kim Zolciak and husband Kroy Biermann's house of horrors: As son KJ, 15, faces sex abuse allegations involving classmate, watch the shock bodycam footage from before teenager's arrest and read the devastating claims of home violence'Kissing virus' infecting 90% of Americans linked to worse symptoms of devastating neurological disorder Read the book so raw and revealing it has started a war of words with the King. In searing detail, EARL SPENCER recalls Charles's behaviour in the hours and days after Diana died Which midterm races should YOU be watching? Enter your zip code in Daily Mail's exclusive election calculator Outcry as cause of death for teen who vanished during trip to'Sex Rock' is revealed Pentagon insiders unleash on Pete Hegseth's'meddling' wife: Whistleblowers reveal her humiliating nickname among staff... how she keeps husband on'extremely tight leash'... and eyebrow-raising behavior in government meetings Lawmakers freak out at Melania Trump's'creepy' AI robots plan for kids as panic grips nation Real reason'insecure' Amanda Seyfried and Thomas Sadoski's marriage collapsed: Insiders reveal perfect storm of his secret struggle and her'palpable' personal issue that ruined everything College volleyball star dead at 20 just weeks after being diagnosed with'rare disorder' as family shares heartbreaking tribute Woman behind the wheel of SUV that slammed into LA bus before NBC chopper crash was'impaired by drugs' as prior convictions are revealed Ole Miss introduces strict new rule for LSU fans attending Lane Kiffin's return with threat to kick them out of stadium Sickly man loses $450k home over $977 in fees... then HOA snatched the property back for a pittance Julia Stiles calls out'diva' Andy Cohen on DWTS after he labeled her'not the greatest dancer' My husband signed me up to a swingers site without my knowledge - then coerced me into sleeping with 15 men.
The first 20 minutes of The Hunger Games: Sunrise on the Reaping blew me away
Versus Mashable's Best: E-readers, robovacs, laptops, earbuds, smart home and more Look Up Mashable Selects Creator Playbook In My Bag Say More Trending Now Back to School Good Connection: Uplifting stories for a digital age Switch Off Mashable Voices All Series The first 20 minutes of'The Hunger Games: Sunrise on the Reaping' blew me away Get the inside scoop on the latest Hunger Games film. Belen Edwards is an Entertainment Reporter at Mashable. She covers movies and TV with a focus on fantasy and science fiction, adaptations, animation, and more nerdy goodness. She is a member of the Critics Choice Association and the Television Critics Association, as well as a Tomatometer-approved critic. All products featured here are independently selected by our editors and writers.
Here's What the AI Apocalypse Could Look Like
Here's What the AI Apocalypse Could Look Like This week on, we discuss three possible AI doomsday scenarios, AI safety, and the unexpected bipartisan alliance forming against AI. The debate of whether AI can kill us has been everywhere lately, but what would an actual AI catastrophe look like? This week, Brian Barrett, Zoë Schiffer, and Leah Feiger break down three real-world scenarios experts worry the most about--including hacked water supplies, bioweapons, and autonomous robots. We also discuss the highlights of Salesforce's annual conference, where OpenAI's Sam Altman and Anthropic's Dario Amodei defended their positions on AI safety. Plus, Leah tells us how this backlash against AI has become a rare bipartisan flashpoint, to the point that Bernie Sanders and Steve Bannon shared a stage over it this week. Washington Won't Be Regulating AI Anytime Soon Write to us at [email protected] . You can always listen to this week's podcast through the audio player on this page, but if you want to subscribe for free to get every episode, here's how: If you're on an iPhone or iPad, open the app called Podcasts, or just tap this link . And instead of just adding to the pile of hot takes that already exist, we're going to walk you through real specific scenarios to the best of our ability about how AI would actually do this, and why the tech CEOs and politicians cannot seem to agree on the way forward. OK, guys, so the debate about AI safety has officially escaped containment. AI researcher Jacob Coxon resigned from Anthropic and posted on X that, The people building AI earnestly believe that it could kill us all by the end of the decade. Anthropic's CEO Dario Amodei has called for a slowdown .