Adopting AI copilots in professional workflows presents opportunities for enhanced productivity, efficiency, and decision making. In this paper, we present results from a six month trial of M365 Copilot conducted at our organisation in 2024. A qualitative interview study was carried out with 27 participants. The study explored user perceptions of M365 Copilot's effectiveness, productivity impact, evolving expectations, ethical concerns, and overall satisfaction. Initial enthusiasm for the tool was met with mixed post trial experiences. While some users found M365 Copilot beneficial for tasks such as email coaching, meeting summaries, and content retrieval, others reported unmet expectations in areas requiring deeper contextual understanding, reasoning, and integration with existing workflows. Ethical concerns were a recurring theme, with users highlighting issues related to data privacy, transparency, and AI bias. While M365 Copilot demonstrated value in specific operational areas, its broader impact remained constrained by usability limitations and the need for human oversight to validate AI generated outputs.

After AlphaFold won the Nobel Prize, protein prediction with deep learning once again became a hot topic. We comprehensively explore advanced deep learning methods applied to protein structure prediction and design. It begins by examining recent innovations in prediction architectures, with detailed discussions on improvements such as diffusion based frameworks and novel pairwise attention modules. The text analyses key components including structure generation, evaluation metrics, multiple sequence alignment processing, and network architecture, thereby illustrating the current state of the art in computational protein modelling. Subsequent chapters focus on practical applications, presenting case studies that range from individual protein predictions to complex biomolecular interactions. Strategies for enhancing prediction accuracy and integrating deep learning techniques with experimental validation are thoroughly explored. The later sections review the industry landscape of protein design, highlighting the transformative role of artificial intelligence in biotechnology and discussing emerging market trends and future challenges. Supplementary appendices provide essential resources such as databases and open source tools, making this volume a valuable reference for researchers and students.

With the availability of virtually infinite number text documents in digital format, automatic comparison of textual data is essential for extracting meaningful insights that are difficult to identify manually. Many existing tools, including AI and large language models, struggle to provide precise and explainable insights into textual similarities. In many cases they determine the similarity between documents as reflected by the text, rather than the similarities between the subjects being discussed in these documents. This study addresses these limitations by developing an n-gram analysis framework designed to compare documents automatically and uncover explainable similarities. A scoring formula is applied to assigns each of the n-grams with a weight, where the weight is higher when the n-grams are more frequent in both documents, but is penalized when the n-grams are more frequent in the English language. Visualization tools like word clouds enhance the representation of these patterns, providing clearer insights. The findings demonstrate that this framework effectively uncovers similarities between text documents, offering explainable insights that are often difficult to identify manually. This non-parametric approach provides a deterministic solution for identifying similarities across various fields, including biographies, scientific literature, historical texts, and more. Code for the method is publicly available.

Tech expert Kurt'CyberGuy' Knutsson joins'Fox & Friends' to discuss the future of AI development in the United States. Vice President JD Vance took a shot at former Vice President Kamala Harris, suggesting her alcohol habits were responsible for her "word salads." Vance's remarks came as he described the difference between how he and Harris have handled the role as vice president, and he speculated about the relationship dynamic between Harris and former President Joe Biden. "Well, I don't have four shots of vodka before every meeting," Vance said in an interview with radio host and Daily Caller editor Vince Coglianese in an interview that aired Thursday. "That's one way I think that Kamala really tried to bring herself into the role, is these word salads. I think I would need the help of a lot of alcohol to answer a question the way that Kamala Harris answered questions."

Data analysis encompasses a spectrum of tasks, from high-level conceptual reasoning to lower-level execution. While AI-powered tools increasingly support execution tasks, there remains a need for intelligent assistance in conceptual tasks. This paper investigates the design of an ordered node-link tree interface augmented with AI-generated information hints and visualizations, as a potential shared representation for hypothesis exploration. Through a design probe (n=22), participants generated diagrams averaging 21.82 hypotheses. Our findings showed that the node-link diagram acts as "guardrails" for hypothesis exploration, facilitating structured workflows, providing comprehensive overviews, and enabling efficient backtracking. The AI-generated information hints, particularly visualizations, aided users in transforming abstract ideas into data-backed concepts while reducing cognitive load. We further discuss how node-link diagrams can support both parallel exploration and iterative refinement in hypothesis formulation, potentially enhancing the breadth and depth of human-AI collaborative data analysis.

This prestigious award is made for excellence in research in the area of autonomous agents. It is intended to recognize researchers in autonomous agents whose current work is an important influence on the field. Professor Shlomo Zilberstein was recognised for his work establishing the field of decentralized Markov Decision Processes (DEC-MDPs), laying the groundwork for decision-theoretic planning in multi-agent systems and multi-agent reinforcement learning (MARL). The selection committee noted that these contributions have become a cornerstone of multi-agent decision-making, influencing researchers and practitioners alike. Shlomo Zilberstein is Professor of Computer Science and former Associate Dean of Research at the University of Massachusetts Amherst. He is a Fellow of AAAI and the ACM, and has received numerous awards, including the UMass Chancellor's Medal, the IFAAMAS Influential Paper Award, and the AAAI Distinguished Service Award.

Problem-Based Learning (PBL) has significantly impacted biomedical engineering (BME) education since its introduction in the early 2000s, effectively enhancing critical thinking and real-world knowledge application among students. With biomedical engineering rapidly converging with artificial intelligence (AI), integrating effective AI education into established curricula has become challenging yet increasingly necessary. Recent advancements, including AI's recognition by the 2024 Nobel Prize, have highlighted the importance of training students comprehensively in biomedical AI. However, effective biomedical AI education faces substantial obstacles, such as diverse student backgrounds, limited personalized mentoring, constrained computational resources, and difficulties in safely scaling hands-on practical experiments due to privacy and ethical concerns associated with biomedical data. To overcome these issues, we conducted a three-year (2021-2023) case study implementing an advanced PBL framework tailored specifically for biomedical AI education, involving 92 undergraduate and 156 graduate students from the joint Biomedical Engineering program of Georgia Institute of Technology and Emory University. Our approach emphasizes collaborative, interdisciplinary problem-solving through authentic biomedical AI challenges. The implementation led to measurable improvements in learning outcomes, evidenced by high research productivity (16 student-authored publications), consistently positive peer evaluations, and successful development of innovative computational methods addressing real biomedical challenges. Additionally, we examined the role of generative AI both as a teaching subject and an educational support tool within the PBL framework. Our study presents a practical and scalable roadmap for biomedical engineering departments aiming to integrate robust AI education into their curricula.

Social platforms have expanded opportunities for deliberation with the comments being used to inform one's opinion. However, using such information to form opinions is challenged by unsubstantiated or false content. To enhance the quality of opinion formation and potentially confer resistance to misinformation, we developed Iffy-Or-Not (ION), a browser extension that seeks to invoke critical thinking when reading texts. With three features guided by argumentation theory, ION highlights fallacious content, suggests diverse queries to probe them with, and offers deeper questions to consider and chat with others about. From a user study (N=18), we found that ION encourages users to be more attentive to the content, suggests queries that align with or are preferable to their own, and poses thought-provoking questions that expands their perspectives. However, some participants expressed aversion to ION due to misalignments with their information goals and thinking predispositions. Potential backfiring effects with ION are discussed.

Accurate 3D multi-object tracking (MOT) is crucial for autonomous driving, as it enables robust perception, navigation, and planning in complex environments. While deep learning-based solutions have demonstrated impressive 3D MOT performance, model-based approaches remain appealing for their simplicity, interpretability, and data efficiency. Conventional model-based trackers typically rely on random vector-based Bayesian filters within the tracking-by-detection (TBD) framework but face limitations due to heuristic data association and track management schemes. In contrast, random finite set (RFS)-based Bayesian filtering handles object birth, survival, and death in a theoretically sound manner, facilitating interpretability and parameter tuning. In this paper, we present OptiPMB, a novel RFS-based 3D MOT method that employs an optimized Poisson multi-Bernoulli (PMB) filter while incorporating several key innovative designs within the TBD framework. Specifically, we propose a measurement-driven hybrid adaptive birth model for improved track initialization, employ adaptive detection probability parameters to effectively maintain tracks for occluded objects, and optimize density pruning and track extraction modules to further enhance overall tracking performance. Extensive evaluations on nuScenes and KITTI datasets show that OptiPMB achieves superior tracking accuracy compared with state-of-the-art methods, thereby establishing a new benchmark for model-based 3D MOT and offering valuable insights for future research on RFS-based trackers in autonomous driving.

Ensuring transparency in educational assessment is increasingly critical, particularly post-pandemic, as demand grows for fairer and more reliable evaluation methods. Comparative Judgement (CJ) offers a promising alternative to traditional assessments, yet concerns remain about its perceived opacity. This paper examines how Bayesian Comparative Judgement (BCJ) enhances transparency by integrating prior information into the judgement process, providing a structured, data-driven approach that improves interpretability and accountability. BCJ assigns probabilities to judgement outcomes, offering quantifiable measures of uncertainty and deeper insights into decision confidence. By systematically tracking how prior data and successive judgements inform final rankings, BCJ clarifies the assessment process and helps identify assessor disagreements. Multi-criteria BCJ extends this by evaluating multiple learning outcomes (LOs) independently, preserving the richness of CJ while producing transparent, granular rankings aligned with specific assessment goals. It also enables a holistic ranking derived from individual LOs, ensuring comprehensive evaluations without compromising detailed feedback. Using a real higher education dataset with professional markers in the UK, we demonstrate BCJ's quantitative rigour and ability to clarify ranking rationales. Through qualitative analysis and discussions with experienced CJ practitioners, we explore its effectiveness in contexts where transparency is crucial, such as high-stakes national assessments. We highlight the benefits and limitations of BCJ, offering insights into its real-world application across various educational settings.