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A review of deep learning-based information fusion techniques for multimodal medical image classification

arXiv.org Artificial Intelligence

Multimodal medical imaging plays a pivotal role in clinical diagnosis and research, as it combines information from various imaging modalities to provide a more comprehensive understanding of the underlying pathology. Recently, deep learning-based multimodal fusion techniques have emerged as powerful tools for improving medical image classification. This review offers a thorough analysis of the developments in deep learning-based multimodal fusion for medical classification tasks. We explore the complementary relationships among prevalent clinical modalities and outline three main fusion schemes for multimodal classification networks: input fusion, intermediate fusion (encompassing single-level fusion, hierarchical fusion, and attention-based fusion), and output fusion. By evaluating the performance of these fusion techniques, we provide insight into the suitability of different network architectures for various multimodal fusion scenarios and application domains. Furthermore, we delve into challenges related to network architecture selection, handling incomplete multimodal data management, and the potential limitations of multimodal fusion. Finally, we spotlight the promising future of Transformer-based multimodal fusion techniques and give recommendations for future research in this rapidly evolving field.


Manipulating Recommender Systems: A Survey of Poisoning Attacks and Countermeasures

arXiv.org Artificial Intelligence

Recommender systems have become an integral part of online services to help users locate specific information in a sea of data. However, existing studies show that some recommender systems are vulnerable to poisoning attacks, particularly those that involve learning schemes. A poisoning attack is where an adversary injects carefully crafted data into the process of training a model, with the goal of manipulating the system's final recommendations. Based on recent advancements in artificial intelligence, such attacks have gained importance recently. While numerous countermeasures to poisoning attacks have been developed, they have not yet been systematically linked to the properties of the attacks. Consequently, assessing the respective risks and potential success of mitigation strategies is difficult, if not impossible. This survey aims to fill this gap by primarily focusing on poisoning attacks and their countermeasures. This is in contrast to prior surveys that mainly focus on attacks and their detection methods. Through an exhaustive literature review, we provide a novel taxonomy for poisoning attacks, formalise its dimensions, and accordingly organise 30+ attacks described in the literature. Further, we review 40+ countermeasures to detect and/or prevent poisoning attacks, evaluating their effectiveness against specific types of attacks. This comprehensive survey should serve as a point of reference for protecting recommender systems against poisoning attacks. The article concludes with a discussion on open issues in the field and impactful directions for future research. A rich repository of resources associated with poisoning attacks is available at https://github.com/tamlhp/awesome-recsys-poisoning.


Enhancing Trust in Autonomous Agents: An Architecture for Accountability and Explainability through Blockchain and Large Language Models

arXiv.org Artificial Intelligence

The deployment of autonomous agents in environments involving human interaction has increasingly raised security concerns. Consequently, understanding the circumstances behind an event becomes critical, requiring the development of capabilities to justify their behaviors to non-expert users. Such explanations are essential in enhancing trustworthiness and safety, acting as a preventive measure against failures, errors, and misunderstandings. Additionally, they contribute to improving communication, bridging the gap between the agent and the user, thereby improving the effectiveness of their interactions. This work presents an accountability and explainability architecture implemented for ROS-based mobile robots. The proposed solution consists of two main components. Firstly, a black box-like element to provide accountability, featuring anti-tampering properties achieved through blockchain technology. Secondly, a component in charge of generating natural language explanations by harnessing the capabilities of Large Language Models (LLMs) over the data contained within the previously mentioned black box. The study evaluates the performance of our solution in three different scenarios, each involving autonomous agent navigation functionalities. This evaluation includes a thorough examination of accountability and explainability metrics, demonstrating the effectiveness of our approach in using accountable data from robot actions to obtain coherent, accurate and understandable explanations, even when facing challenges inherent in the use of autonomous agents in real-world scenarios.


Beyond the Speculative Game: A Survey of Speculative Execution in Large Language Models

arXiv.org Artificial Intelligence

With the increasingly giant scales of (causal) large language models (LLMs), the inference efficiency comes as one of the core concerns along the improved performance. In contrast to the memory footprint, the latency bottleneck seems to be of greater importance as there can be billions of requests to a LLM (e.g., GPT-4) per day. The bottleneck is mainly due to the autoregressive innateness of LLMs, where tokens can only be generated sequentially during decoding. To alleviate the bottleneck, the idea of speculative execution, which originates from the field of computer architecture, is introduced to LLM decoding in a \textit{draft-then-verify} style. Under this regime, a sequence of tokens will be drafted in a fast pace by utilizing some heuristics, and then the tokens shall be verified in parallel by the LLM. As the costly sequential inference is parallelized, LLM decoding speed can be significantly boosted. Driven by the success of LLMs in recent couple of years, a growing literature in this direction has emerged. Yet, there lacks a position survey to summarize the current landscape and draw a roadmap for future development of this promising area. To meet this demand, we present the very first survey paper that reviews and unifies literature of speculative execution in LLMs (e.g., blockwise parallel decoding, speculative decoding, etc.) in a comprehensive framework and a systematic taxonomy. Based on the taxonomy, we present a critical review and comparative analysis of the current arts. Finally we highlight various key challenges and future directions to further develop the area.


A Mechanism-Based Approach to Mitigating Harms from Persuasive Generative AI

arXiv.org Artificial Intelligence

Recent generative AI systems have demonstrated more advanced persuasive capabilities and are increasingly permeating areas of life where they can influence decision-making. Generative AI presents a new risk profile of persuasion due the opportunity for reciprocal exchange and prolonged interactions. This has led to growing concerns about harms from AI persuasion and how they can be mitigated, highlighting the need for a systematic study of AI persuasion. The current definitions of AI persuasion are unclear and related harms are insufficiently studied. Existing harm mitigation approaches prioritise harms from the outcome of persuasion over harms from the process of persuasion. In this paper, we lay the groundwork for the systematic study of AI persuasion. We first put forward definitions of persuasive generative AI. We distinguish between rationally persuasive generative AI, which relies on providing relevant facts, sound reasoning, or other forms of trustworthy evidence, and manipulative generative AI, which relies on taking advantage of cognitive biases and heuristics or misrepresenting information. We also put forward a map of harms from AI persuasion, including definitions and examples of economic, physical, environmental, psychological, sociocultural, political, privacy, and autonomy harm. We then introduce a map of mechanisms that contribute to harmful persuasion. Lastly, we provide an overview of approaches that can be used to mitigate against process harms of persuasion, including prompt engineering for manipulation classification and red teaming. Future work will operationalise these mitigations and study the interaction between different types of mechanisms of persuasion.


The Power of the Noisy Channel: Unsupervised End-to-End Task-Oriented Dialogue with LLMs

arXiv.org Artificial Intelligence

Training task-oriented dialogue systems typically requires turn-level annotations for interacting with their APIs: e.g. a dialogue state and the system actions taken at each step. These annotations can be costly to produce, error-prone, and require both domain and annotation expertise. With advances in LLMs, we hypothesize unlabelled data and a schema definition are sufficient for building a working task-oriented dialogue system, completely unsupervised. Using only (1) a well-defined API schema (2) a set of unlabelled dialogues between a user and agent, we develop a novel approach for inferring turn-level annotations as latent variables using a noisy channel model. We iteratively improve these pseudo-labels with expectation-maximization (EM), and use the inferred labels to train an end-to-end dialogue agent. Evaluating our approach on the MultiWOZ benchmark, our method more than doubles the dialogue success rate of a strong GPT-3.5 baseline.


A Survey of Deep Long-Tail Classification Advancements

arXiv.org Artificial Intelligence

Many data distributions in the real world are hardly uniform. Instead, skewed and long-tailed distributions of various kinds are commonly observed. This poses an interesting problem for machine learning, where most algorithms assume or work well with uniformly distributed data. The problem is further exacerbated by current state-of-the-art deep learning models requiring large volumes of training data. As such, learning from imbalanced data remains a challenging research problem and a problem that must be solved as we move towards more real-world applications of deep learning. In the context of class imbalance, state-of-the-art (SOTA) accuracies on standard benchmark datasets for classification typically fall less than 75%, even for less challenging datasets such as CIFAR100. Nonetheless, there has been progress in this niche area of deep learning. To this end, in this survey, we provide a taxonomy of various methods proposed for addressing the problem of long-tail classification, focusing on works that happened in the last few years under a single mathematical framework. We also discuss standard performance metrics, convergence studies, feature distribution and classifier analysis. We also provide a quantitative comparison of the performance of different SOTA methods and conclude the survey by discussing the remaining challenges and future research direction.


Atomas: Hierarchical Alignment on Molecule-Text for Unified Molecule Understanding and Generation

arXiv.org Artificial Intelligence

Molecule-and-text cross-modal representation learning has emerged as a promising direction for enhancing the quality of molecular representation, thereby improving performance in various scientific fields, including drug discovery and materials science. Existing studies adopt a global alignment approach to learn the knowledge from different modalities. These global alignment approaches fail to capture fine-grained information, such as molecular fragments and their corresponding textual description, which is crucial for downstream tasks. Furthermore, it is incapable to model such information using a similar global alignment strategy due to data scarcity of paired local part annotated data from existing datasets. In this paper, we propose Atomas, a multi-modal molecular representation learning framework to jointly learn representations from SMILES string and text. We design a Hierarchical Adaptive Alignment model to concurrently learn the fine-grained fragment correspondence between two modalities and align these representations of fragments in three levels. Additionally, Atomas's end-to-end training framework incorporates the tasks of understanding and generating molecule, thereby supporting a wider range of downstream tasks. In the retrieval task, Atomas exhibits robust generalization ability and outperforms the baseline by 30.8% of recall@1 on average. In the generation task, Atomas achieves state-of-the-art results in both molecule captioning task and molecule generation task. Moreover, the visualization of the Hierarchical Adaptive Alignment model further confirms the chemical significance of our approach. Our codes can be found at https://anonymous.4open.science/r/Atomas-03C3.


Parameter Efficient Fine Tuning: A Comprehensive Analysis Across Applications

arXiv.org Artificial Intelligence

The rise of deep learning has marked significant progress in fields such as computer vision, natural language processing, and medical imaging, primarily through the adaptation of pre-trained models for specific tasks. Traditional fine-tuning methods, involving adjustments to all parameters, face challenges due to high computational and memory demands. This has led to the development of Parameter Efficient Fine-Tuning (PEFT) techniques, which selectively update parameters to balance computational efficiency with performance. This review examines PEFT approaches, offering a detailed comparison of various strategies highlighting applications across different domains, including text generation, medical imaging, protein modeling, and speech synthesis. By assessing the effectiveness of PEFT methods in reducing computational load, speeding up training, and lowering memory usage, this paper contributes to making deep learning more accessible and adaptable, facilitating its wider application and encouraging innovation in model optimization. Ultimately, the paper aims to contribute towards insights into PEFT's evolving landscape, guiding researchers and practitioners in overcoming the limitations of conventional fine-tuning approaches.


Bias patterns in the application of LLMs for clinical decision support: A comprehensive study

arXiv.org Artificial Intelligence

Large Language Models (LLMs) have emerged as powerful candidates to inform clinical decision-making processes. While these models play an increasingly prominent role in shaping the digital landscape, two growing concerns emerge in healthcare applications: 1) to what extent do LLMs exhibit social bias based on patients' protected attributes (like race), and 2) how do design choices (like architecture design and prompting strategies) influence the observed biases? To answer these questions rigorously, we evaluated eight popular LLMs across three question-answering (QA) datasets using clinical vignettes (patient descriptions) standardized for bias evaluations. We employ red-teaming strategies to analyze how demographics affect LLM outputs, comparing both general-purpose and clinically-trained models. Our extensive experiments reveal various disparities (some significant) across protected groups. We also observe several counter-intuitive patterns such as larger models not being necessarily less biased and fined-tuned models on medical data not being necessarily better than the general-purpose models. Furthermore, our study demonstrates the impact of prompt design on bias patterns and shows that specific phrasing can influence bias patterns and reflection-type approaches (like Chain of Thought) can reduce biased outcomes effectively. Consistent with prior studies, we call on additional evaluations, scrutiny, and enhancement of LLMs used in clinical decision support applications.