Model Extraction Attacks (MEAs) threaten modern machine learning systems by enabling adversaries to steal models, exposing intellectual property and training data. With the increasing deployment of machine learning models in distributed computing environments, including cloud, edge, and federated learning settings, each paradigm introduces distinct vulnerabilities and challenges. Without a unified perspective on MEAs across these distributed environments, organizations risk fragmented defenses, inadequate risk assessments, and substantial economic and privacy losses. This survey is motivated by the urgent need to understand how the unique characteristics of cloud, edge, and federated deployments shape attack vectors and defense requirements. We systematically examine the evolution of attack methodologies and defense mechanisms across these environments, demonstrating how environmental factors influence security strategies in critical sectors such as autonomous vehicles, healthcare, and financial services. By synthesizing recent advances in MEAs research and discussing the limitations of current evaluation practices, this survey provides essential insights for developing robust and adaptive defense strategies. Our comprehensive approach highlights the importance of integrating protective measures across the entire distributed computing landscape to ensure the secure deployment of machine learning models.

The application of large language models (LLMs) in healthcare has the potential to revolutionize clinical decision-making, medical research, and patient care. As LLMs are increasingly integrated into healthcare systems, several critical challenges must be addressed to ensure their reliable and ethical deployment. These challenges include truthfulness, where models generate misleading information; privacy, with risks of unintentional data retention; robustness, requiring defenses against adversarial attacks; fairness, addressing biases in clinical outcomes; explainability, ensuring transparent decision-making; and safety, mitigating risks of misinformation and medical errors. Recently, researchers have begun developing benchmarks and evaluation frameworks to systematically assess the trustworthiness of LLMs. However, the trustworthiness of LLMs in healthcare remains underexplored, lacking a systematic review that provides a comprehensive understanding and future insights into this area. This survey bridges this gap by providing a comprehensive overview of the recent research of existing methodologies and solutions aimed at mitigating the above risks in healthcare. By focusing on key trustworthiness dimensions including truthfulness, privacy and safety, robustness, fairness and bias, and explainability, we present a thorough analysis of how these issues impact the reliability and ethical use of LLMs in healthcare. This paper highlights ongoing efforts and offers insights into future research directions to ensure the safe and trustworthy deployment of LLMs in healthcare.

This thesis presents a framework that integrates state-of-the-art generative AI models for real-time creation of three-dimensional (3D) objects in augmented reality (AR) environments. The primary goal is to convert diverse inputs, such as images and speech, into accurate 3D models, enhancing user interaction and immersion. Key components include advanced object detection algorithms, user-friendly interaction techniques, and robust AI models like Shap-E for 3D generation. Leveraging Vision Language Models (VLMs) and Large Language Models (LLMs), the system captures spatial details from images and processes textual information to generate comprehensive 3D objects, seamlessly integrating virtual objects into real-world environments. The framework demonstrates applications across industries such as gaming, education, retail, and interior design. It allows players to create personalized in-game assets, customers to see products in their environments before purchase, and designers to convert real-world objects into 3D models for real-time visualization. A significant contribution is democratizing 3D model creation, making advanced AI tools accessible to a broader audience, fostering creativity and innovation. The framework addresses challenges like handling multilingual inputs, diverse visual data, and complex environments, improving object detection and model generation accuracy, as well as loading 3D models in AR space in real-time. In conclusion, this thesis integrates generative AI and AR for efficient 3D model generation, enhancing accessibility and paving the way for innovative applications and improved user interactions in AR environments.

Current financial LLM agent benchmarks are inadequate. They prioritize task performance while ignoring fundamental safety risks. Threats like hallucinations, temporal misalignment, and adversarial vulnerabilities pose systemic risks in high-stakes financial environments, yet existing evaluation frameworks fail to capture these risks. We take a firm position: traditional benchmarks are insufficient to ensure the reliability of LLM agents in finance. To address this, we analyze existing financial LLM agent benchmarks, finding safety gaps and introducing ten risk-aware evaluation metrics. Through an empirical evaluation of both API-based and open-weight LLM agents, we reveal hidden vulnerabilities that remain undetected by conventional assessments. To move the field forward, we propose the Safety-Aware Evaluation Agent (SAEA), grounded in a three-level evaluation framework that assesses agents at the model level (intrinsic capabilities), workflow level (multi-step process reliability), and system level (integration robustness). Our findings highlight the urgent need to redefine LLM agent evaluation standards by shifting the focus from raw performance to safety, robustness, and real world resilience.

Constitutional AI (CAI) guides LLM behavior using constitutions, but identifying which principles are most effective for model alignment remains an open challenge. We introduce the C3AI framework (\textit{Crafting Constitutions for CAI models}), which serves two key functions: (1) selecting and structuring principles to form effective constitutions before fine-tuning; and (2) evaluating whether fine-tuned CAI models follow these principles in practice. By analyzing principles from AI and psychology, we found that positively framed, behavior-based principles align more closely with human preferences than negatively framed or trait-based principles. In a safety alignment use case, we applied a graph-based principle selection method to refine an existing CAI constitution, improving safety measures while maintaining strong general reasoning capabilities. Interestingly, fine-tuned CAI models performed well on negatively framed principles but struggled with positively framed ones, in contrast to our human alignment results. This highlights a potential gap between principle design and model adherence. Overall, C3AI provides a structured and scalable approach to both crafting and evaluating CAI constitutions.

In recent years, advancements in generative artificial intelligence have led to the development of sophisticated tools capable of mimicking diverse artistic styles, opening new possibilities for digital creativity and artistic expression. This paper presents a critical assessment of the style replication capabilities of contemporary generative models, evaluating their strengths and limitations across multiple dimensions. We examine how effectively these models reproduce traditional artistic styles while maintaining structural integrity and compositional balance in the generated images. The analysis is based on a new large dataset of AI-generated works imitating artistic styles of the past, holding potential for a wide range of applications: the "AI-pastiche" dataset. The study is supported by extensive user surveys, collecting diverse opinions on the dataset and investigation both technical and aesthetic challenges, including the ability to generate outputs that are realistic and visually convincing, the versatility of models in handling a wide range of artistic styles, and the extent to which they adhere to the content and stylistic specifications outlined in prompts. This paper aims to provide a comprehensive overview of the current state of generative tools in style replication, offering insights into their technical and artistic limitations, potential advancements in model design and training methodologies, and emerging opportunities for enhancing digital artistry, human-AI collaboration, and the broader creative landscape.

Reinforcement learning (RL) has gained traction for its success in solving complex tasks for robotic applications. However, its deployment on physical robots remains challenging due to safety risks and the comparatively high costs of training. To avoid these problems, RL agents are often trained on simulators, which introduces a new problem related to the gap between simulation and reality. This paper presents an RL pipeline designed to help reduce the reality gap and facilitate developing and deploying RL policies for real-world robotic systems. The pipeline organizes the RL training process into an initial step for system identification and three training stages: core simulation training, high-fidelity simulation, and real-world deployment, each adding levels of realism to reduce the sim-to-real gap. Each training stage takes an input policy, improves it, and either passes the improved policy to the next stage or loops it back for further improvement. This iterative process continues until the policy achieves the desired performance. The pipeline's effectiveness is shown through a case study with the Boston Dynamics Spot mobile robot used in a surveillance application. The case study presents the steps taken at each pipeline stage to obtain an RL agent to control the robot's position and orientation.

Low-Rank Adaptation (LoRA) has become ubiquitous for efficiently fine-tuning foundation models. However, federated fine-tuning using LoRA is challenging due to suboptimal updates arising from traditional federated averaging of individual adapters. Existing solutions either incur prohibitively high communication cost that scales linearly with the number of clients or suffer from performance degradation due to limited expressivity. We introduce Federated Silver Bullet (Fed-SB), a novel approach for federated fine-tuning of LLMs using LoRA-SB, a recently proposed low-rank adaptation method. LoRA-SB optimally aligns the optimization trajectory with the ideal low-rank full fine-tuning projection by learning a small square matrix (R) between adapters B and A, keeping other components fixed. Direct averaging of R guarantees exact updates, substantially reducing communication cost, which remains independent of the number of clients, and enables scalability. Fed-SB achieves state-of-the-art performance across commonsense reasoning, arithmetic reasoning, and language inference tasks while reducing communication costs by up to 230x. In private settings, Fed-SB further improves performance by (1) reducing trainable parameters, thereby lowering the noise required for differential privacy and (2) avoiding noise amplification introduced by other methods. Overall, Fed-SB establishes a new Pareto frontier in the tradeoff between communication and performance, offering an efficient and scalable solution for both private and non-private federated fine-tuning. Our code is publicly available at https://github.com/CERT-Lab/fed-sb.

Equivariant network architectures are a well-established tool for predicting invariant or equivariant quantities. However, almost all learning problems considered in this context feature a global symmetry, i.e. each point of the underlying space is transformed with the same group element, as opposed to a local ``gauge'' symmetry, where each point is transformed with a different group element, exponentially enlarging the size of the symmetry group. Gauge equivariant networks have so far mainly been applied to problems in quantum chromodynamics. Here, we introduce a novel application domain for gauge-equivariant networks in the theory of topological condensed matter physics. We use gauge equivariant networks to predict topological invariants (Chern numbers) of multiband topological insulators. The gauge symmetry of the network guarantees that the predicted quantity is a topological invariant. We introduce a novel gauge equivariant normalization layer to stabilize the training and prove a universal approximation theorem for our setup. We train on samples with trivial Chern number only but show that our models generalize to samples with non-trivial Chern number. We provide various ablations of our setup. Our code is available at https://github.com/sitronsea/GENet/tree/main.

Drug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate prediction of how drugs interact with their targets and the development of new drugs by using better methods and technologies have immense potential to speed up this process, ultimately leading to faster delivery of life-saving medications. Traditional methods used for drug-target interaction prediction show limitations, particularly in capturing complex relationships between drugs and their targets. As an outcome, deep learning models have been presented to overcome the challenges of interaction prediction through their precise and efficient end results. By outlining promising research avenues and models, each with a different solution but similar to the problem, this paper aims to give researchers a better idea of methods for even more accurate and efficient prediction of drug-target interaction, ultimately accelerating the development of more effective drugs. A total of 180 prediction methods for drug-target interactions were analyzed throughout the period spanning 2016 to 2025 using different frameworks based on machine learning, mainly deep learning and graph neural networks. Additionally, this paper discusses the novelty, architecture, and input representation of these models.