Explainability has been widely stated as a cornerstone of the responsible and trustworthy use of machine learning models. With the ubiquitous use of Deep Neural Network (DNN) models expanding to risk-sensitive and safety-critical domains, many methods have been proposed to explain the decisions of these models. Recent years have also seen concerted efforts that have shown how such explanations can be distorted (attacked) by minor input perturbations. While there have been many surveys that review explainability methods themselves, there has been no effort hitherto to assimilate the different methods and metrics proposed to study the robustness of explanations of DNN models. In this work, we present a comprehensive survey of methods that study, understand, attack, and defend explanations of DNN models. We also present a detailed review of different metrics used to evaluate explanation methods, as well as describe attributional attack and defense methods. We conclude with lessons and take-aways for the community towards ensuring robust explanations of DNN model predictions.

Abstract: Structure-based drug design uses three-dimensional geometric information of macromolecules, such as proteins or nucleic acids, to identify suitable ligands. Geometric deep learning, an emerging concept of neural-network-based machine learning, has been applied to macromolecular structures. This review provides an overview of the recent applications of geometric deep learning in bioorganic and medicinal chemistry, highlighting its potential for structure-based drug discovery and design. Emphasis is placed on molecular property prediction, ligand binding site and pose prediction, and structure-based de novo molecular design. The current challenges and opportunities are highlighted, and a forecast of the future of geometric deep learning for drug discovery is presented.

Abstract: he paper proposes a novel hybrid discovery Radiomics framework that simultaneously integrates temporal and spatial features extracted from non-thin chest Computed Tomography (CT) slices to predict Lung Adenocarcinoma (LUAC) malignancy with minimum expert involvement. Lung cancer is the leading cause of mortality from cancer worldwide and has various histologic types, among which LUAC has recently been the most prevalent. LUACs are classified as pre-invasive, minimally invasive, and invasive adenocarcinomas. Timely and accurate knowledge of the lung nodules malignancy leads to a proper treatment plan and reduces the risk of unnecessary or late surgeries. Currently, chest CT scan is the primary imaging modality to assess and predict the invasiveness of LUACs.

Identified as the key for further enhancing competitiveness and workforce reinforcement, AI has the potential to be included in various operation processes. One such field, AI in visual inspection – with computer vision and machine learning on the rise – has been becoming more popular thanks to the engagement of top players across industries. In the recent online sharing, experts from FPT Corporation, FPT Software, Landing AI, and Schaeffler discussed their visions for the future of'AI in Real-time Quality Inspection'. All parties emphasised on the use of data-centric approach to shorten AI training duration in machine learning and addressed critical issues faced by brownfields factories. Until just recently, factory owners were equipped with rule-based vision inspection, which required IT experts to write pages of rules for the algorithm to detect product defects.

Each BUS image is fed into the trained generative network to obtain the boundary of the tumor, and then 13 statistical features from that boundary are computed: fractal dimension, lacunarity, convex hull, convexity, circularity, area, perimeter, centroid, minor and major axis length, smoothness, Hu moments (6) and central moments (order 3 and below). Exhaustive Feature Selection (EFS) algorithm is used to select the best set of features. The EFS algorithm indicates that the fractal dimension, lacunarity, convex hull, and centroid are the 4 optimal features. The selected features are fed into a Random Forest classifier, which is later trained to discriminate between benign and malignant tumors. Each BUS image is fed into the trained generative network to obtain the boundary of the tumor, and then 13 statistical features from that boundary are computed: fractal dimension, lacunarity, convex hull, convexity, circularity, area, perimeter, centroid, minor and major axis length, smoothness, Hu moments (6) and central moments (order 3 and below).

Pioneering artificial intelligence (AI) which automatically diagnoses lung diseases – such as tuberculosis and pneumonia – could ease winter pressures on hospitals, University of the West of Scotland researchers believe. Tuberculosis and pneumonia – potentially serious infections which mainly affect the lungs –often require a combination of different diagnostic tests,– such as CT scans, blood tests, X-rays, and ultrasounds. These tests can be expensive, with often lengthy waiting times for results. Developed by UWS, the revolutionary technology – originally created to quickly detect Covid-19 from X-ray images – has been proven to automatically identify a range of different lung diseases in a matter of minutes, with around 98 per cent accuracy. UWS researcher Professor Naeem Ramzan said: "Systems such as this could prove to be crucial for busy medical teams worldwide."

With most technical fields, there exists a delay between fundamental academic research and practical industrial uptake. Whilst some sciences have robust and well-established processes for commercialisation, such as the pharmaceutical practice of regimented drug trials, other fields face transitory periods in which fundamental academic advancements diffuse gradually into the space of commerce and industry. For the still relatively young field of Automated/Autonomous Machine Learning (AutoML/AutonoML), that transitory period is under way, spurred on by a burgeoning interest from broader society. Yet, to date, little research has been undertaken to assess the current state of this dissemination and its uptake. Thus, this review makes two primary contributions to knowledge around this topic. Firstly, it provides the most up-to-date and comprehensive survey of existing AutoML tools, both open-source and commercial. Secondly, it motivates and outlines a framework for assessing whether an AutoML solution designed for real-world application is 'performant'; this framework extends beyond the limitations of typical academic criteria, considering a variety of stakeholder needs and the human-computer interactions required to service them. Thus, additionally supported by an extensive assessment and comparison of academic and commercial case-studies, this review evaluates mainstream engagement with AutoML in the early 2020s, identifying obstacles and opportunities for accelerating future uptake.

Empathy is a vital factor that contributes to mutual understanding, and joint problem-solving. In recent years, a growing number of studies have recognized the benefits of empathy and started to incorporate empathy in conversational systems. We refer to this topic as empathetic conversational systems. To identify the critical gaps and future opportunities in this topic, this paper examines this rapidly growing field using five review dimensions: (i) conceptual empathy models and frameworks, (ii) adopted empathy-related concepts, (iii) datasets and algorithmic techniques developed, (iv) evaluation strategies, and (v) state-of-the-art approaches. The findings show that most studies have centered on the use of the EMPATHETICDIALOGUES dataset, and the text-based modality dominates research in this field. Studies mainly focused on extracting features from the messages of the users and the conversational systems, with minimal emphasis on user modeling and profiling. Notably, studies that have incorporated emotion causes, external knowledge, and affect matching in the response generation models, have obtained significantly better results. For implementation in diverse real-world settings, we recommend that future studies should address key gaps in areas of detecting and authenticating emotions at the entity level, handling multimodal inputs, displaying more nuanced empathetic behaviors, and encompassing additional dialogue system features.

Coreference resolution (CR) is one of the most challenging areas of natural language processing. This task seeks to identify all textual references to the same real-world entity. Research in this field is divided into coreference resolution and anaphora resolution. Due to its application in textual comprehension and its utility in other tasks such as information extraction systems, document summarization, and machine translation, this field has attracted considerable interest. Consequently, it has a significant effect on the quality of these systems. This article reviews the existing corpora and evaluation metrics in this field. Then, an overview of the coreference algorithms, from rule-based methods to the latest deep learning techniques, is provided. Finally, coreference resolution and pronoun resolution systems in Persian are investigated.

Despite extensive research efforts in recent years, computational argumentation (CA) remains one of the most challenging areas of natural language processing. The reason for this is the inherent complexity of the cognitive processes behind human argumentation, which integrate a plethora of different types of knowledge, ranging from topic-specific facts and common sense to rhetorical knowledge. The integration of knowledge from such a wide range in CA requires modeling capabilities far beyond many other natural language understanding tasks. Existing research on mining, assessing, reasoning over, and generating arguments largely acknowledges that much more knowledge is needed to accurately model argumentation computationally. However, a systematic overview of the types of knowledge introduced in existing CA models is missing, hindering targeted progress in the field. Adopting the operational definition of knowledge as any task-relevant normative information not provided as input, the survey paper at hand fills this gap by (1) proposing a taxonomy of types of knowledge required in CA tasks, (2) systematizing the large body of CA work according to the reliance on and exploitation of these knowledge types for the four main research areas in CA, and (3) outlining and discussing directions for future research efforts in CA.