This paper presents an introduction to the state-of-the-art in anomaly and change-point detection. On the one hand, the main concepts needed to understand the vast scientific literature on those subjects are introduced. On the other, a selection of important surveys and books, as well as two selected active research topics in the field, are presented.

Natural Language Processing (NLP) has been revolutionized by the use of Pre-trained Language Models (PLMs) such as BERT. Despite setting new records in nearly every NLP task, PLMs still face a number of challenges including poor interpretability, weak reasoning capability, and the need for a lot of expensive annotated data when applied to downstream tasks. By integrating external knowledge into PLMs, \textit{\underline{K}nowledge-\underline{E}nhanced \underline{P}re-trained \underline{L}anguage \underline{M}odels} (KEPLMs) have the potential to overcome the above-mentioned limitations. In this paper, we examine KEPLMs systematically through a series of studies. Specifically, we outline the common types and different formats of knowledge to be integrated into KEPLMs, detail the existing methods for building and evaluating KEPLMS, present the applications of KEPLMs in downstream tasks, and discuss the future research directions. Researchers will benefit from this survey by gaining a quick and comprehensive overview of the latest developments in this field.

Artificial intelligence (AI) in its various forms finds more and more its way into complex distributed systems. For instance, it is used locally, as part of a sensor system, on the edge for low-latency high-performance inference, or in the cloud, e.g. for data mining. Modern complex systems, such as connected vehicles, are often part of an Internet of Things (IoT). To manage complexity, architectures are described with architecture frameworks, which are composed of a number of architectural views connected through correspondence rules. Despite some attempts, the definition of a mathematical foundation for architecture frameworks that are suitable for the development of distributed AI systems still requires investigation and study. In this paper, we propose to extend the state of the art on architecture framework by providing a mathematical model for system architectures, which is scalable and supports co-evolution of different aspects for example of an AI system. Based on Design Science Research, this study starts by identifying the challenges with architectural frameworks. Then, we derive from the identified challenges four rules and we formulate them by exploiting concepts from category theory. We show how compositional thinking can provide rules for the creation and management of architectural frameworks for complex systems, for example distributed systems with AI. The aim of the paper is not to provide viewpoints or architecture models specific to AI systems, but instead to provide guidelines based on a mathematical formulation on how a consistent framework can be built up with existing, or newly created, viewpoints. To put in practice and test the approach, the identified and formulated rules are applied to derive an architectural framework for the EU Horizon 2020 project ``Very efficient deep learning in the IoT" (VEDLIoT) in the form of a case study.

Identifying cybersecurity discussions in open forums at scale is a topic of great interest for the purpose of mitigating and understanding modern cyber threats [1-3]. The challenge is that these discussions are typically quite noisy (i.e., they contain community known synonyms or acronyms or slang) and it is difficult to get labelled data in order to train resilient NLP (natural language processing) topic classifiers. Additionally, it is important that a tool that detects cybersecurity discussions in internet text sources is scalable and offers low errors rates (in particular, both low false negative rates and low false positive rates). In order to address the challenges of finding relevant cybersecurity labelled data, we use a technique that gathers posts or articles from different internet sources that have user defined topic labels. We then collect and label the training text as being cybersecurity related or not based on the subset of labels that the text source offers.

We're Cruise, a self-driving service designed for the cities we love. We're building the world's most advanced, self-driving vehicles to safely connect people to the places, things, and experiences they care about. We believe self-driving vehicles will help save lives, reshape cities, give back time in transit, and restore freedom of movement for many. Cruisers have the opportunity to grow and develop while learning from leaders at the forefront of their fields. With a culture of internal mobility, there's an opportunity to thrive in a variety of disciplines.

As the world continues to move towards automation, architecture has become an increasingly attractive solution for architects and urban planners. By combining the power of artificial intelligence (AI) with traditional architecture and urban design techniques, architecture offers a new and innovative approach to designing future cities and structures. This paper will explore architecture's potential to change how we design and build our cities and structures. Architecture is a computer-aided design that incorporates elements of artificial intelligence into traditional architectural and urban design principles. The architecture allows machine learning algorithms to assist in creating designs from basic building blocks, such as walls, windows, doors, arches, etc. Architecture also explores the potential of using simulated environments to test and evaluate a wide range of design solutions.

Artificial intelligence (AI) in the form of deep learning bears promise for drug discovery and chemical biology, $\textit{e.g.}$, to predict protein structure and molecular bioactivity, plan organic synthesis, and design molecules $\textit{de novo}$. While most of the deep learning efforts in drug discovery have focused on ligand-based approaches, structure-based drug discovery has the potential to tackle unsolved challenges, such as affinity prediction for unexplored protein targets, binding-mechanism elucidation, and the rationalization of related chemical kinetic properties. Advances in deep learning methodologies and the availability of accurate predictions for protein tertiary structure advocate for a $\textit{renaissance}$ in structure-based approaches for drug discovery guided by AI. This review summarizes the most prominent algorithmic concepts in structure-based deep learning for drug discovery, and forecasts opportunities, applications, and challenges ahead.

In recent years, the exponential proliferation of smart devices with their intelligent applications poses severe challenges on conventional cellular networks. Such challenges can be potentially overcome by integrating communication, computing, caching, and control (i4C) technologies. In this survey, we first give a snapshot of different aspects of the i4C, comprising background, motivation, leading technological enablers, potential applications, and use cases. Next, we describe different models of communication, computing, caching, and control (4C) to lay the foundation of the integration approach. We review current state-of-the-art research efforts related to the i4C, focusing on recent trends of both conventional and artificial intelligence (AI)-based integration approaches. We also highlight the need for intelligence in resources integration. Then, we discuss integration of sensing and communication (ISAC) and classify the integration approaches into various classes. Finally, we propose open challenges and present future research directions for beyond 5G networks, such as 6G.

Data-centric AI is at the center of a fundamental shift in software engineering where machine learning becomes the new software, powered by big data and computing infrastructure. Here software engineering needs to be re-thought where data becomes a first-class citizen on par with code. One striking observation is that a significant portion of the machine learning process is spent on data preparation. Without good data, even the best machine learning algorithms cannot perform well. As a result, data-centric AI practices are now becoming mainstream. Unfortunately, many datasets in the real world are small, dirty, biased, and even poisoned. In this survey, we study the research landscape for data collection and data quality primarily for deep learning applications. Data collection is important because there is lesser need for feature engineering for recent deep learning approaches, but instead more need for large amounts of data. For data quality, we study data validation, cleaning, and integration techniques. Even if the data cannot be fully cleaned, we can still cope with imperfect data during model training using robust model training techniques. In addition, while bias and fairness have been less studied in traditional data management research, these issues become essential topics in modern machine learning applications. We thus study fairness measures and unfairness mitigation techniques that can be applied before, during, or after model training. We believe that the data management community is well poised to solve these problems.

With the research directions described in this thesis, we seek to address the critical challenges in designing recommender systems that can understand the dynamics of continuous-time event sequences. We follow a ground-up approach, i.e., first, we address the problems that may arise due to the poor quality of CTES data being fed into a recommender system. Later, we handle the task of designing accurate recommender systems. To improve the quality of the CTES data, we address a fundamental problem of overcoming missing events in temporal sequences. Moreover, to provide accurate sequence modeling frameworks, we design solutions for points-of-interest recommendation, i.e., models that can handle spatial mobility data of users to various POI check-ins and recommend candidate locations for the next check-in. Lastly, we highlight that the capabilities of the proposed models can have applications beyond recommender systems, and we extend their abilities to design solutions for large-scale CTES retrieval and human activity prediction. A significant part of this thesis uses the idea of modeling the underlying distribution of CTES via neural marked temporal point processes (MTPP). Traditional MTPP models are stochastic processes that utilize a fixed formulation to capture the generative mechanism of a sequence of discrete events localized in continuous time. In contrast, neural MTPP combine the underlying ideas from the point process literature with modern deep learning architectures. The ability of deep-learning models as accurate function approximators has led to a significant gain in the predictive prowess of neural MTPP models. In this thesis, we utilize and present several neural network-based enhancements for the current MTPP frameworks for the aforementioned real-world applications.