This paper provides an overview of the historical progression of distributed optimization techniques, tracing their development from early duality-based methods pioneered by Dantzig, Wolfe, and Benders in the 1960s to the emergence of the Augmented Lagrangian Alternating Direction Inexact Newton (ALADIN) algorithm. The initial focus on Lagrangian relaxation for convex problems and decomposition strategies led to the refinement of methods like the Alternating Direction Method of Multipliers (ADMM). The resurgence of interest in distributed optimization in the late 2000s, particularly in machine learning and imaging, demonstrated ADMM's practical efficacy and its unifying potential. This overview also highlights the emergence of the proximal center method and its applications in diverse domains. Furthermore, the paper underscores the distinctive features of ALADIN, which offers convergence guarantees for non-convex scenarios without introducing auxiliary variables, differentiating it from traditional augmentation techniques. In essence, this work encapsulates the historical trajectory of distributed optimization and underscores the promising prospects of ALADIN in addressing non-convex optimization challenges.

Transformer-based language models (TLMs) have widely been recognized to be a cutting-edge technology for the successful development of deep-learning-based solutions to problems and applications that require natural language processing and understanding. Like for other textual domains, TLMs have indeed pushed the state-of-the-art of AI approaches for many tasks of interest in the legal domain. Despite the first Transformer model being proposed about six years ago, there has been a rapid progress of this technology at an unprecedented rate, whereby BERT and related models represent a major reference, also in the legal domain. This article provides the first systematic overview of TLM-based methods for AI-driven problems and tasks in the legal sphere. A major goal is to highlight research advances in this field so as to understand, on the one hand, how the Transformers have contributed to the success of AI in supporting legal processes, and on the other hand, what are the current limitations and opportunities for further research development.

With the big popularity and success of Judea Pearl's original causality book, this review covers the main topics updated in the second edition in 2009 and illustrates an easy-to-follow causal inference strategy in a forecast scenario. It further discusses some potential benefits and challenges for causal inference with time series forecasting when modeling the counterfactuals, estimating the uncertainty and incorporating prior knowledge to estimate causal effects in different forecasting scenarios.

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were applied in practice.The field of Medical AI faces various challenges, in terms of building user trust, complying with regulations, using data ethically.Explainable AI (XAI) aims to enable humans understand AI and trust its results. This paper presents a literature review on the recent developments of XAI solutions for medical decision support, based on a representative sample of 198 articles published in recent years. The systematic synthesis of the relevant articles resulted in several findings. (1) model-agnostic XAI techniques were mostly employed in these solutions, (2) deep learning models are utilized more than other types of machine learning models, (3) explainability was applied to promote trust, but very few works reported the physicians participation in the loop, (4) visual and interactive user interface is more useful in understanding the explanation and the recommendation of the system. More research is needed in collaboration between medical and AI experts, that could guide the development of suitable frameworks for the design, implementation, and evaluation of XAI solutions in medicine.

Ensuring alignment, which refers to making models behave in accordance with human intentions [1,2], has become a critical task before deploying large language models (LLMs) in real-world applications. For instance, OpenAI devoted six months to iteratively aligning GPT-4 before its release [3]. However, a major challenge faced by practitioners is the lack of clear guidance on evaluating whether LLM outputs align with social norms, values, and regulations. This obstacle hinders systematic iteration and deployment of LLMs. To address this issue, this paper presents a comprehensive survey of key dimensions that are crucial to consider when assessing LLM trustworthiness. The survey covers seven major categories of LLM trustworthiness: reliability, safety, fairness, resistance to misuse, explainability and reasoning, adherence to social norms, and robustness. Each major category is further divided into several sub-categories, resulting in a total of 29 sub-categories. Additionally, a subset of 8 sub-categories is selected for further investigation, where corresponding measurement studies are designed and conducted on several widely-used LLMs. The measurement results indicate that, in general, more aligned models tend to perform better in terms of overall trustworthiness. However, the effectiveness of alignment varies across the different trustworthiness categories considered. This highlights the importance of conducting more fine-grained analyses, testing, and making continuous improvements on LLM alignment. By shedding light on these key dimensions of LLM trustworthiness, this paper aims to provide valuable insights and guidance to practitioners in the field. Understanding and addressing these concerns will be crucial in achieving reliable and ethically sound deployment of LLMs in various applications.

Hypernetworks, or hypernets in short, are neural networks that generate weights for another neural network, known as the target network. They have emerged as a powerful deep learning technique that allows for greater flexibility, adaptability, dynamism, faster training, information sharing, and model compression etc. Hypernets have shown promising results in a variety of deep learning problems, including continual learning, causal inference, transfer learning, weight pruning, uncertainty quantification, zero-shot learning, natural language processing, and reinforcement learning etc. Despite their success across different problem settings, currently, there is no review available to inform the researchers about the developments and to help in utilizing hypernets. To fill this gap, we review the progress in hypernets. We present an illustrative example to train deep neural networks using hypernets and propose categorizing hypernets based on five design criteria as inputs, outputs, variability of inputs and outputs, and architecture of hypernets. We also review applications of hypernets across different deep learning problem settings, followed by a discussion of general scenarios where hypernets can be effectively employed. Finally, we discuss the challenges and future directions that remain under-explored in the field of hypernets. We believe that hypernetworks have the potential to revolutionize the field of deep learning. They offer a new way to design and train neural networks, and they have the potential to improve the performance of deep learning models on a variety of tasks. Through this review, we aim to inspire further advancements in deep learning through hypernetworks.

In biomedical image analysis, the applicability of deep learning methods is directly impacted by the quantity of image data available. This is due to deep learning models requiring large image datasets to provide high-level performance. Generative Adversarial Networks (GANs) have been widely utilized to address data limitations through the generation of synthetic biomedical images. GANs consist of two models. The generator, a model that learns how to produce synthetic images based on the feedback it receives. The discriminator, a model that classifies an image as synthetic or real and provides feedback to the generator. Throughout the training process, a GAN can experience several technical challenges that impede the generation of suitable synthetic imagery. First, the mode collapse problem whereby the generator either produces an identical image or produces a uniform image from distinct input features. Second, the non-convergence problem whereby the gradient descent optimizer fails to reach a Nash equilibrium. Thirdly, the vanishing gradient problem whereby unstable training behavior occurs due to the discriminator achieving optimal classification performance resulting in no meaningful feedback being provided to the generator. These problems result in the production of synthetic imagery that is blurry, unrealistic, and less diverse. To date, there has been no survey article outlining the impact of these technical challenges in the context of the biomedical imagery domain. This work presents a review and taxonomy based on solutions to the training problems of GANs in the biomedical imaging domain. This survey highlights important challenges and outlines future research directions about the training of GANs in the domain of biomedical imagery.

This paper studies Byzantine-robust stochastic optimization over a decentralized network, where every agent periodically communicates with its neighbors to exchange local models, and then updates its own local model by stochastic gradient descent (SGD). The performance of such a method is affected by an unknown number of Byzantine agents, which conduct adversarially during the optimization process. To the best of our knowledge, there is no existing work that simultaneously achieves a linear convergence speed and a small learning error. We observe that the learning error is largely dependent on the intrinsic stochastic gradient noise. Motivated by this observation, we introduce two variance reduction methods, stochastic average gradient algorithm (SAGA) and loopless stochastic variance-reduced gradient (LSVRG), to Byzantine-robust decentralized stochastic optimization for eliminating the negative effect of the stochastic gradient noise. The two resulting methods, BRAVO-SAGA and BRAVO-LSVRG, enjoy both linear convergence speeds and stochastic gradient noise-independent learning errors. Such learning errors are optimal for a class of methods based on total variation (TV)-norm regularization and stochastic subgradient update. We conduct extensive numerical experiments to demonstrate their effectiveness under various Byzantine attacks.

The Alexa Prize program has empowered numerous university students to explore, experiment, and showcase their talents in building conversational agents through challenges like the SocialBot Grand Challenge and the TaskBot Challenge. As conversational agents increasingly appear in multimodal and embodied contexts, it is important to explore the affordances of conversational interaction augmented with computer vision and physical embodiment. This paper describes the SimBot Challenge, a new challenge in which university teams compete to build robot assistants that complete tasks in a simulated physical environment. This paper provides an overview of the SimBot Challenge, which included both online and offline challenge phases. We describe the infrastructure and support provided to the teams including Alexa Arena, the simulated environment, and the ML toolkit provided to teams to accelerate their building of vision and language models. We summarize the approaches the participating teams took to overcome research challenges and extract key lessons learned. Finally, we provide analysis of the performance of the competing SimBots during the competition.

In this paper, we introduce a strategy for identifying textual saliency in large-scale language models applied to classification tasks. In visual networks where saliency is more well-studied, saliency is naturally localized through the convolutional layers of the network; however, the same is not true in modern transformer-stack networks used to process natural language. We adapt gradient-based saliency methods for these networks, propose a method for evaluating the degree of semantic coherence of each layer, and demonstrate consistent improvement over numerous other methods for textual saliency on multiple benchmark classification datasets. Our approach requires no additional training or access to labelled data, and is comparatively very computationally efficient.