Continuum soft robots are mechanical systems entirely made of continuously deformable elements. This design solution aims to bring robots closer to invertebrate animals and soft appendices of vertebrate animals (e.g., an elephant's trunk, a monkey's tail). This work aims to introduce the control theorist perspective to this novel development in robotics. We aim to remove the barriers to entry into this field by presenting existing results and future challenges using a unified language and within a coherent framework. Indeed, the main difficulty in entering this field is the wide variability of terminology and scientific backgrounds, making it quite hard to acquire a comprehensive view on the topic. Another limiting factor is that it is not obvious where to draw a clear line between the limitations imposed by the technology not being mature yet and the challenges intrinsic to this class of robots. In this work, we argue that the intrinsic effects are the continuum or multi-body dynamics, the presence of a non-negligible elastic potential field, and the variability in sensing and actuation strategies.

Recent years have witnessed the wide adoption of large language models (LLM) in different fields, especially natural language processing and computer vision. Such a trend can also be observed in recommender systems (RS). However, most of related work treat LLM as a component of the conventional recommendation pipeline (e.g., as a feature extractor) which may not be able to fully leverage the generative power of LLM. Instead of separating the recommendation process into multiple stages such as score computation and re-ranking, this process can be simplified to one stage with LLM: directly generating recommendations from the complete pool of items. This survey reviews the progress, methods and future directions of LLM-based generative recommendation by examining three questions: 1) What generative recommendation is, 2) Why RS should advance to generative recommendation, and 3) How to implement LLM-based generative recommendation for various RS tasks. We hope that the survey can provide the context and guidance needed to explore this interesting and emerging topic.

Instant delivery services, such as food delivery and package delivery, have achieved explosive growth in recent years by providing customers with daily-life convenience. An emerging research area within these services is service Route\&Time Prediction (RTP), which aims to estimate the future service route as well as the arrival time of a given worker. As one of the most crucial tasks in those service platforms, RTP stands central to enhancing user satisfaction and trimming operational expenditures on these platforms. Despite a plethora of algorithms developed to date, there is no systematic, comprehensive survey to guide researchers in this domain. To fill this gap, our work presents the first comprehensive survey that methodically categorizes recent advances in service route and time prediction. We start by defining the RTP challenge and then delve into the metrics that are often employed. Following that, we scrutinize the existing RTP methodologies, presenting a novel taxonomy of them. We categorize these methods based on three criteria: (i) type of task, subdivided into only-route prediction, only-time prediction, and joint route\&time prediction; (ii) model architecture, which encompasses sequence-based and graph-based models; and (iii) learning paradigm, including Supervised Learning (SL) and Deep Reinforcement Learning (DRL). Conclusively, we highlight the limitations of current research and suggest prospective avenues. We believe that the taxonomy, progress, and prospects introduced in this paper can significantly promote the development of this field.

Transformers have emerged as the state of the art neural network architecture for natural language processing and computer vision. In the foundation model paradigm, large transformer models (BERT, GPT3/4, Bloom, ViT) are pre-trained on self-supervised tasks such as word or image masking, and then, adapted through fine-tuning for downstream user applications including instruction following and Question Answering. While many approaches have been developed for model fine-tuning including low-rank weight update strategies (eg. LoRA), underlying mathematical principles that enable network adaptation without knowledge loss remain poorly understood. Here, we introduce a differential geometry framework, functionally invariant paths (FIP), that provides flexible and continuous adaptation of neural networks for a range of machine learning goals and network sparsification objectives. We conceptualize the weight space of a neural network as a curved Riemannian manifold equipped with a metric tensor whose spectrum defines low rank subspaces in weight space that accommodate network adaptation without loss of prior knowledge. We formalize adaptation as movement along a geodesic path in weight space while searching for networks that accommodate secondary objectives. With modest computational resources, the FIP algorithm achieves comparable to state of the art performance on continual learning and sparsification tasks for language models (BERT), vision transformers (ViT, DeIT), and the CNNs. Broadly, we conceptualize a neural network as a mathematical object that can be iteratively transformed into distinct configurations by the path-sampling algorithm to define a sub-manifold of weight space that can be harnessed to achieve user goals.

Robust, fast, and accurate human state - 6D pose and posture - estimation remains a challenging problem. For real-world applications, the ability to estimate the human state in real-time is highly desirable. In this paper, we present BodySLAM++, a fast, efficient, and accurate human and camera state estimation framework relying on visual-inertial data. BodySLAM++ extends an existing visual-inertial state estimation framework, OKVIS2, to solve the dual task of estimating camera and human states simultaneously. Our system improves the accuracy of both human and camera state estimation with respect to baseline methods by 26% and 12%, respectively, and achieves real-time performance at 15+ frames per second on an Intel i7-model CPU. Experiments were conducted on a custom dataset containing both ground truth human and camera poses collected with an indoor motion tracking system.

Bruna Moreira da Silva is a PhD student at The University of Melbourne. Her research interests are in bioinformatics, immunoinformatics and machine learning to advance Global Health. David B. Ascher is the Director of Biotechnology at the University of Queensland and head of Computational Biology and Clinical Informatics at the Baker Institute and Systems and Computational Biology at Bio21 Institute. He is interested in developing and applying computational tools to assist leveraging clinical and omics data for drug discovery and personalised medicine. Nicholas Geard is an Associate Professor at the School of Computing and Information Systems at the University of Melbourne and Director of the Melbourne Data Analytics Platform. He is a computer scientist specialising in computational simulation applied to a range of problems in health and epidemiology. Douglas E. V. Pires is an Associate Professor in Digital Health at the School of Computing and Information Systems at the University of Melbourne and group leader at the Bio21 Institute. He is a computer scientist and bioinformatician specialising in machine learning and AI and the development of the next generation of tools to analyse omics data, and guide drug discovery and personalised medicine. ABSTRACT Antibodies, a prominent class of approved biologics, play a crucial role in detecting foreign antigens. The effectiveness of antigen neutralisation and elimination hinges upon the strength, sensitivity, and specificity of the paratope-epitope interaction, which demands resource-intensive experimental techniques for characterisation. In recent years, artificial intelligence and machine learning methods have made significant strides, revolutionising the prediction of protein structures and their complexes. The past decade has also witnessed the evolution of computational approaches aiming to support immunotherapy design. This review focuses on the progress of machine learning-based tools and their frameworks in the domain of B-cell immunotherapy design, encompassing linear and conformational epitope prediction, paratope prediction, and antibody design. We mapped the most commonly used data sources, evaluation metrics, and method availability and thoroughly assessed their significance and limitations, discussing the main challenges ahead. INTRODUCTION Therapeutic antibodies are a rapidly growing class of biopharmaceuticals with potentially exceptional antigen specificity and affinity. Their ability to detect and eliminate a wide array of foreign threats makes them suitable for a range of potential therapeutic and diagnostic applications. Antibody and antigen engineering have been greatly benefited by the evolution of research in computational biology, leading to innovative approaches in screening antibody targets, optimising their biochemical and physical properties, predicting and optimising binding affinity and understanding escape mutations [1].

Big models, exemplified by Large Language Models (LLMs), are models typically pre-trained on massive data and comprised of enormous parameters, which not only obtain significantly improved performance across diverse tasks but also present emergent capabilities absent in smaller models. However, the growing intertwining of big models with everyday human lives poses potential risks and might cause serious social harm. Therefore, many efforts have been made to align LLMs with humans to make them better follow user instructions and satisfy human preferences. Nevertheless, `what to align with' has not been fully discussed, and inappropriate alignment goals might even backfire. In this paper, we conduct a comprehensive survey of different alignment goals in existing work and trace their evolution paths to help identify the most essential goal. Particularly, we investigate related works from two perspectives: the definition of alignment goals and alignment evaluation. Our analysis encompasses three distinct levels of alignment goals and reveals a goal transformation from fundamental abilities to value orientation, indicating the potential of intrinsic human values as the alignment goal for enhanced LLMs. Based on such results, we further discuss the challenges of achieving such intrinsic value alignment and provide a collection of available resources for future research on the alignment of big models.

The COVID-19 pandemic has a devastating impact globally, claiming millions of lives and causing significant social and economic disruptions. In order to optimize decision-making and allocate limited resources, it is essential to identify COVID-19 symptoms and determine the severity of each case. Machine learning algorithms offer a potent tool in the medical field, particularly in mining clinical datasets for useful information and guiding scientific decisions. Association rule mining is a machine learning technique for extracting hidden patterns from data. This paper presents an application of association rule mining based Apriori algorithm to discover symptom patterns from COVID-19 patients. The study, using 2875 patient's records, identified the most common signs and symptoms as apnea (72%), cough (64%), fever (59%), weakness (18%), myalgia (14.5%), and sore throat (12%). The proposed method provides clinicians with valuable insight into disease that can assist them in managing and treating it effectively.

The area of Neurosymbolic Artificial Intelligence (Neurosymbolic AI) is rapidly developing and has become a popular research topic, encompassing sub-fields such as Neurosymbolic Deep Learning (Neurosymbolic DL) and Neurosymbolic Reinforcement Learning (Neurosymbolic RL). Compared to traditional learning methods, Neurosymbolic AI offers significant advantages by simplifying complexity and providing transparency and explainability. Reinforcement Learning(RL), a long-standing Artificial Intelligence(AI) concept that mimics human behavior using rewards and punishment, is a fundamental component of Neurosymbolic RL, a recent integration of the two fields that has yielded promising results. The aim of this paper is to contribute to the emerging field of Neurosymbolic RL by conducting a literature survey. Our evaluation focuses on the three components that constitute Neurosymbolic RL: neural, symbolic, and RL. We categorize works based on the role played by the neural and symbolic parts in RL, into three taxonomies:Learning for Reasoning, Reasoning for Learning and Learning-Reasoning. These categories are further divided into sub-categories based on their applications. Furthermore, we analyze the RL components of each research work, including the state space, action space, policy module, and RL algorithm. Additionally, we identify research opportunities and challenges in various applications within this dynamic field.

Modern NLP breakthrough includes large multilingual models capable of performing tasks across more than 100 languages. State-of-the-art language models came a long way, starting from the simple one-hot representation of words capable of performing tasks like natural language understanding, common-sense reasoning, or question-answering, thus capturing both the syntax and semantics of texts. At the same time, language models are expanding beyond our known language boundary, even competitively performing over very low-resource dialects of endangered languages. However, there are still problems to solve to ensure an equitable representation of texts through a unified modeling space across language and speakers. In this survey, we shed light on this iterative progression of multilingual text representation and discuss the driving factors that ultimately led to the current state-of-the-art. Subsequently, we discuss how the full potential of language democratization could be obtained, reaching beyond the known limits and what is the scope of improvement in that space.