We are developing a phoneme based.

In this paper, several techniques for addressing this problem are discussed in the context of an isolated word recognition task.

Eight neural net and conventional pattern classifiers (Bayesianunimodal Gaussian, k-nearest neighbor, standard back-propagation, adaptive-stepsize back-propagation, hypersphere, feature-map, learning vector quantizer, and binary decision tree) were implemented on a serial computer and compared using two speech recognition and two artificial tasks. Error rates were statistically equivalent on almost all tasks, but classifiers differed by orders of magnitude in memory requirements, training time, classification time, and ease of adaptivity. Nearest-neighbor classifiers trained rapidly but required the most memory. Tree classifiers provided rapid classification but were complex to adapt. Back-propagation classifiers typically required long training times and had intermediate memory requirements. These results suggest that classifier selection should often depend more heavily on practical considerations concerning memory and computation resources, and restrictions on training and classification times than on error rate.

Analytic solutions to the information-theoretic evolution equation of the connection strength of a three-layer feedforward neural net for visual information processing are presented. The results are (1) the receptive fields of the feature-analysing cells correspond to the eigenvector of the maximum eigenvalue of the Fredholm integral equation of the first kind derived from the evolution equation of the connection strength; (2) a symmetry-breaking mechanism (parity-violation) has been identified to be responsible for the changes of the morphology of the receptive field; (3) the conditions for the formation of different morphologies are explicitly identified.

The input/output properties of a 2 compartment model neuron are systematically explored. Taken from the work of MacGregor (MacGregor, 1987), the model neuron compartments contain several active conductances, including a potassium conductance in the dendritic compartment driven by the accumulation of intradendritic calcium. Dynamics of the conductances and potentials are governed by a set of coupled first order differential equations which are integrated numerically. There are a set of 17 internal parameters to this model, specificying conductance rate constants, time constants, thresholds, etc. To study parameter sensitivity, a set of trials were run in which the input driving the neuron is kept fixed while each internal parameter is varied with all others left fixed. To study the input/output relation, the input to the dendrite (a square wave) was varied (in frequency and magnitude) while all internal parameters of the system were left flXed, and the resulting output firing rate and bursting rate was counted. The input/output relation of the model neuron studied turns out to be much more sensitive to modulation of certain dendritic potassium current parameters than to plasticity of synapse efficacy per se (the amount of current influx due to synapse activation). This would in turn suggest, as has been recently observed experimentally, that the potassium current may be as or more important a focus of neural plasticity than synaptic efficacy.

We show that localized activity patterns in a layer of cells, collective excitations, can induce the formation of modular structures in the anatomical connections via a Hebbian learning mechanism. The networks are spatially homogeneous before learning, but the spontaneous emergence of localized collective excitations and subsequently modularity in the connection patterns breaks translational symmetry. This spontaneous symmetry breaking phenomenon is similar to those which drive pattern formation in reaction-diffusion systems. We have identified requirements on the patterns of lateral connections and on the gains of internal units which are essential for the development of modularity. These essential requirements will most likely remain operative when more complicated (and biologically realistic) models are considered.

In the mammalian visual cortex, orientation-selective'simple cells' which detect straight lines may be adapted to detect curved lines instead. We test a biologically plausible, Hebbian, single-neuron model, which learns oriented receptive fields upon exposure to unstructured (noise) input and maintains orientation selectivity upon exposure to edges or bars of all orientations and positions. This model can also learn arc-shaped receptive fields upon exposure to an environment of only circular rings. Thus, new experiments which try to induce an abnormal (curved) receptive field may provide insight into the plasticity of simple cells. The model suggests that exposing cells to only a single spatial frequency may induce more striking spatial frequency and orientation dependent effects than heretofore observed.

We present a model of catecholamine effects in a network of neural-like elements. We argue that changes in the responsivity of individual elements do not affect their ability to detect a signal and ignore noise. However. the same changes in cell responsivity in a network of such elements do improve the signal detection performance of the network as a whole. We show how this result can be used in a computer simulation of behavior to account for the effect of eNS stimulants on the signal detection performance of human subjects.

We outline a computational model of the development and regeneration of specific eye-brain circuits. The model comprises a self-organizing map-forming network which uses local Hebb rules.

It is well-known that neural responses in particular brain regions are spatially organized, but no general principles have been developed that relate the structure of a brain map to the nature of the associated computation. On parallel computers, maps of a sort quite similar to brain maps arise when a computation is distributed across multiple processors. In this paper we will discuss the relationship between maps and computations on these computers and suggest how similar considerations might also apply to maps in the brain. 1 INTRODUCTION A great deal of effort in experimental and theoretical neuroscience is devoted to recording and interpreting spatial patterns of neural activity. A variety of map patterns have been observed in different brain regions and, presumably, these patterns reflect something about the nature of the neural computations being carried out in these regions. To date, however, there have been no general principles for interpreting the structure of a brain map in terms of properties of the associated computation.