The mortality related to cervical cancer can be substantially reduced through early detection and treatment. However, current detection techniques, such as Pap smear and colposcopy, fail to achieve a concurrently high sensitivity and specificity. In vivo fluorescence spectroscopy is a technique which quickly, noninvasively and quantitatively probes the biochemical and morphological changes that occur in precancerous tissue. RBF ensemble algorithms based on such spectra provide automated, and near realtime implementation of pre-cancer detection in the hands of nonexperts. The results are more reliable, direct and accurate than those achieved by either human experts or multivariate statistical algorithms. 1 Introduction Cervical carcinoma is the second most common cancer in women worldwide, exceeded only by breast cancer (Ramanujam et al., 1996). The mortality related to cervical cancer can be reduced if this disease is detected at the precancerous state, known as squamous intraepitheliallesion (SIL). Currently, a Pap smear is used to 982 K. Turner, N. Ramanujam, R. Richards-Kortum and J. Ghosh screen for cervical cancer {Kurman et al., 1994}. In a Pap test, a large number of cells obtained by scraping the cervical epithelium are smeared onto a slide which is then fixed and stained for cytologic examination.

In cellular telephone systems, an important problem is to dynamically allocate the communication resource (channels) so as to maximize service in a stochastic caller environment. This problem is naturally formulated as a dynamic programming problem and we use a reinforcement learning (RL) method to find dynamic channel allocation policies that are better than previous heuristic solutions. The policies obtained perform well for a broad variety of call traffic patterns.

BC Cancer Agency 601 West 10th Ave, Epidemiology 601 West 10th Ave, Epidemiology Vancouver BC Canada V5Z 1L3 Vancouver BC Canada V5Z 1L3 tap@comp.vuw.ac.nz Abstract Epidemiological data is traditionally analyzed with very simple techniques. Flexible models, such as neural networks, have the potential to discover unanticipated features in the data. However, to be useful, flexible models must have effective control on overfitting. This paper reports on a comparative study of the predictive quality of neural networks and other flexible models applied to real and artificial epidemiological data. The results suggest that there are no major unanticipated complex features in the real data, and also demonstrate that MacKay's [1995] Bayesian neural network methodology provides effective control on overfitting while retaining the ability to discover complex features in the artificial data. 1 Introduction Traditionally, very simple statistical techniques are used in the analysis of epidemiological studies.

This paper shows how the prices of option contracts traded in financial markets can be tracked sequentially by means of the Extended Kalman Filter algorithm. I consider call and put option pairs with identical strike price and time of maturity as a two output nonlinear system. The Black-Scholes approach popular in Finance literature and the Radial Basis Functions neural network are used in modelling the nonlinear system generating these observations. I show how both these systems may be identified recursively using the EKF algorithm. I present results of simulations on some FTSE 100 Index options data and discuss the implications of viewing the pricing problem in this sequential manner. 1 INTRODUCTION Data from the financial markets has recently been of much interest to the neural computing community. The complexity of the underlying macroeconomic system and how traders react to the flow of information leads to highly nonlinear relationships between observations.

The Neurothermostat is an adaptive controller that regulates indoor air temperature in a residence by switching a furnace on or off. The task is framed as an optimal control problem in which both comfort and energy costs are considered as part of the control objective. Because the consequences of control decisions are delayed in time, the N eurothermostat must anticipate heating demands with predictive models of occupancy patterns and the thermal response of the house and furnace. Occupancy pattern prediction is achieved by a hybrid neural net / lookup table. The Neurothermostat searches, at each discrete time step, for a decision sequence that minimizes the expected cost over a fixed planning horizon.

Artificial Neural Networks can be used to predict future returns of stocks in order to take financial decisions. Should one build a separate network for each stock or share the same network for all the stocks? In this paper we also explore other alternatives, in which some layers are shared and others are not shared. When the prediction of future returns for different stocks are viewed as different tasks, sharing some parameters across stocks is a form of multi-task learning. In a series of experiments with Canadian stocks, we obtain yearly returns that are more than 14% above various benchmarks.

Predictions oflifetimes of dynamically allocated objects can be used to improve time and space efficiency of dynamic memory management in computer programs. Barrett and Zorn [1993] used a simple lifetime predictor and demonstrated this improvement on a variety of computer programs. In this paper, we use decision trees to do lifetime prediction on the same programs and show significantly better prediction. Our method also has the advantage that during training we can use a large number of features and let the decision tree automatically choose the relevant subset.

In a communication network in which traffic sources can be dynamically added or removed, an access controller must decide when to accept or reject a new traffic source based on whether, if added, acceptable service would be given to all carried sources. Unlike best-effort services such as the internet, we consider the case where traffic sources are given quality of service (QoS) guarantees such as maximum delay, delay variation, or loss rate. The goal of the controller is to accept the maximal number of users while guaranteeing QoS. To accommodate diverse sources such as constant bit rate voice, variablerate video, and bursty computer data, packet-based protocols are used. We consider QOS in terms of lost packets (Le.

A typical problem in experiments performed at high energy accelerators aimed at studying novel effects in the field of Elementary Particle Physics is that of preselecting interesting interactions at as early a stage as possible, in order to keep the data volume manageable. One class of events that have to be eliminated is due to cosmic muons that pass all trigger conditions.

It has been suggested that long-range intrinsic connections in striate cortex may play a role in contour extraction (Gilbert et aI., 1996). A number of recent physiological and psychophysical studies have examined the possible role of long range connections in the modulation of contrast detection thresholds (Polat and Sagi, 1993,1994; Kapadia et aI., 1995; Kovacs and Julesz, 1994) and various pre-attentive detection tasks (Kovacs and Julesz, 1993; Field et aI., 1993). We have developed a network architecture based on the anatomical connectivity of striate cortex, as well as the temporal dynamics of neuronal processing, that is able to reproduce the observed experimental results. The network has been tested on real images and has applications in terms of identifying salient contours in automatic image processing systems. 1 INTRODUCTION Vision is an active process, and one of the earliest, preattentive actions in visual processing is the identification of the salient contours in a scene. We propose that this process depends upon two properties of striate cortex: the pattern of horizontal connections between orientation columns, and temporal synchronization of cell responses. In particular, we propose that perceptual salience is directly related to the degree of cell synchronization. We present results of network simulations that account for recent physiological and psychophysical "pop-out" experiments, and which successfully extract salient contours from real images.