We introduce a novel algorithm, termed PPA (Performance Prediction Algorithm), that quantitatively measures the contributions of elements of a neural system to the tasks it performs. The algorithm identifies the neurons or areas which participate in a cognitive or behavioral task, given data about performance decrease in a small set of lesions. It also allows the accurate prediction of performances due to multi-element lesions. The effectiveness of the new algorithm is demonstrated in two models of recurrent neural networks with complex interactions among the elements. The algorithm is scalable and applicable to the analysis of large neural networks. Given the recent advances in reversible inactivation techniques, it has the potential to significantly contribute to the understanding of the organization of biological nervous systems, and to shed light on the long-lasting debate about local versus distributed computation in the brain.

The human figure exhibits complex and rich dynamic behavior that is both nonlinear and time-varying. Effective models of human dynamics can be learned from motion capture data using switching linear dynamic system (SLDS) models. We present results for human motion synthesis, classification, and visual tracking using learned SLDS models. Since exact inference in SLDS is intractable, we present three approximate inference algorithms and compare their performance. In particular, a new variational inference algorithm is obtained by casting the SLDS model as a Dynamic Bayesian Network. Classification experiments show the superiority of SLDS over conventional HMM's for our problem domain.

What can a single neuron compute? Abstract In this paper we formulate a description of the computation performed by a neuron as a combination of dimensional reduction and nonlinearity. We implement this description for the Hodgkin Huxley model, identify the most relevant dimensions and find the nonlinearity. A two dimensional description already captures a significant fraction of the information that spikes carry about dynamic inputs. This description also shows that computation in the Hodgkin-Huxley model is more complex than a simple integrateand-fire or perceptron model. 1 Introduction Classical neural network models approximate neurons as devices that sum their inputs and generate a nonzero output if the sum exceeds a threshold.

The resulting combinatorial problem - finding the best agreement half-space over an input sample - is NP hard to approximate to within some constant factor. We suggest a way to circumvent this theoretical bound by introducing a new measure of success for such algorithms. An algorithm is ILmargin successful if the agreement ratio of the half-space it outputs is as good as that of any half-space once training points that are inside the ILmargins of its separating hyper-plane are disregarded. We prove crisp computational complexity results with respect to this success measure: On one hand, for every positive IL, there exist efficient (poly-time) ILmargin successful learning algorithms. On the other hand, we prove that unless P NP, there is no algorithm that runs in time polynomial in the sample size and in 1/ IL that is ILmargin successful for all IL O. 1 Introduction We consider the computational complexity of learning linear perceptrons for arbitrary (Le.

Neurons in area V4 have relatively large receptive fields (RFs), so multiple visual features are simultaneously "seen" by these cells. Recordings from single V 4 neurons suggest that simultaneously presented stimuli compete to set the output firing rate, and that attention acts to isolate individual features by biasing the competition in favor of the attended object. We propose that both stimulus competition and attentional biasing arise from the spatial segregation of afferent synapses onto different regions of the excitable dendritic tree of V 4 neurons. The pattern of feedforward, stimulus-driven inputs follows from a Hebbian rule: excitatory afferents with similar RFs tend to group together on the dendritic tree, avoiding randomly located inhibitory inputs with similar RFs. The same principle guides the formation of inputs that mediate attentional modulation.

Condensation, a form of likelihood-weighted particle filtering, has been successfully used to infer the shapes of highly constrained "active" contours in video sequences. However, when the contours are highly flexible (e.g. for tracking fingers of a hand), a computationally burdensome number of particles is needed to successfully approximate the contour distribution. We show how the Metropolis algorithm can be used to update a particle set representing a distribution over contours at each frame in a video sequence. We compare this method to condensation using a video sequence that requires highly flexible contours, and show that the new algorithm performs dramatically better that the condensation algorithm. We discuss the incorporation of this method into the "active contour" framework where a shape-subspace is used constrain shape variation.

Large margin linear classification methods have been successfully applied to many applications. For a linearly separable problem, it is known that under appropriate assumptions, the expected misclassification error of the computed "optimal hyperplane" approaches zero at a rate proportional to the inverse training sample size. This rate is usually characterized by the margin and the maximum norm of the input data. In this paper, we argue that another quantity, namely the robustness of the input data distribution, also plays an important role in characterizing the convergence behavior of expected misclassification error. Based on this concept of robustness, we show that for a large margin separable linear classification problem, the expected misclassification error may converge exponentially in the number of training sample size.

Vapnik's result that the expectation of the generalisation error ofthe optimal hyperplane is bounded by the expectation of the ratio of the number of support vectors to the number of training examples is extended to a broad class of kernel machines. The class includes Support Vector Machines for soft margin classification and regression, and Regularization Networks with a variety of kernels and cost functions. We show that key inequalities in Vapnik's result become equalities once "the classification error" is replaced by "the margin error", with the latter defined as an instance with positive cost. In particular we show that expectations of the true margin error and the empirical margin error are equal, and that the sparse solutions for kernel machines are possible only if the cost function is "partially" insensitive. 1 Introduction Minimization of regularized risk is a backbone of several recent advances in machine learning, including Support Vector Machines (SVM) [13], Regularization Networks (RN) [5] or Gaussian Processes [15]. Such a machine is typically implemented as a weighted sum of a kernel function evaluated for pairs composed of a data vector in question and a number of selected training vectors, so called support vectors.

The strong correlation between the frequency of words and their naming latency has been well documented. However, as early as 1973, the Age of Acquisition (AoA) of a word was alleged to be the actual variable of interest, but these studies seem to have been ignored in most of the literature. Recently, there has been a resurgence of interest in AoA. While some studies have shown that frequency has no effect when AoA is controlled for, more recent studies have found independent contributions of frequency and AoA. Connectionist models have repeatedly shown strong effects of frequency, but little attention has been paid to whether they can also show AoA effects. Indeed, several researchers have explicitly claimed that they cannot show AoA effects. In this work, we explore these claims using a simple feed forward neural network. We find a significant contribution of AoA to naming latency, as well as conditions under which frequency provides an independent contribution.

Exact inference in large, richly connected noisy-OR networks is intractable, and most approximate inference algorithms tend to concentrate on a small number of most probable configurations of the hidden variables under the posterior. We presented an "inclusive" variational method for bipartite noisy-OR networks that favors including all probable configurations, at the cost of including some improbable configurations. The method fits a tree to the posterior distribution sequentially, i.e., one observation at a time. Results on an ensemble of QMR-DT type networks show that the method performs better than local probability propagation and a variational upper bound for ranking most probable diseases.