Statistical learning and probabilistic inference techniques are used to infer the hand position of a subject from multi-electrode recordings of neural activity in motor cortex. First, an array of electrodes provides training data of neural firing conditioned on hand kinematics. We learn a nonparametric representation of this firing activity using a Bayesian model and rigorously compare it with previous models using cross-validation. Second, we infer a posterior probability distribution over hand motion conditioned on a sequence of neural test data using Bayesian inference. The learned firing models of multiple cells are used to define a non-Gaussian likelihood term which is combined with a prior probability for the kinematics. A particle filtering method is used to represent, update, and propagate the posterior distribution over time. The approach is compared with traditional linear filtering methods; the results suggest that it may be appropriate for neural prosthetic applications.

We consider a problem of blind source separation from a set of instantaneous linear mixtures, where the mixing matrix is unknown. It was discovered recently, that exploiting the sparsity of sources in an appropriate representation according to some signal dictionary, dramatically improves the quality of separation. In this work we use the property of multi scale transforms, such as wavelet or wavelet packets, to decompose signals into sets of local features with various degrees of sparsity. We use this intrinsic property for selecting the best (most sparse) subsets of features for further separation. The performance of the algorithm is verified on noise-free and noisy data. Experiments with simulated signals, musical sounds and images demonstrate significant improvement of separation quality over previously reported results.

We propose randomized techniques for speeding up Kernel Principal Component Analysis on three levels: sampling and quantization of the Gram matrix in training, randomized rounding in evaluating the kernel expansions, and random projections in evaluating the kernel itself. In all three cases, we give sharp bounds on the accuracy of the obtained approximations. Rather intriguingly, all three techniques can be viewed as instantiations of the following idea: replace the kernel function by a "randomized kernel" which behaves like in expectation.

Guided by an initial idea of building a complex (non linear) decision surface with maximal local margin in input space, we give a possible geometrical intuition as to why K-Nearest Neighbor (KNN) algorithms often perform more poorly than SVMs on classification tasks. We then propose modified K-Nearest Neighbor algorithms to overcome the perceived problem. The approach is similar in spirit to Tangent Distance, but with invariances inferred from the local neighborhood rather than prior knowledge. Experimental results on real world classification tasks suggest that the modified KNN algorithms often give a dramatic improvement over standard KNN and perform as well or better than SVMs.

A new class of Support Vector Machine (SVM) that is applicable to sequential-pattern recognition such as speech recognition is developed by incorporating an idea of nonlinear time alignment into the kernel function. Since the time-alignment operation of sequential pattern is embedded in the new kernel function, standard SVM training and classification algorithms can be employed without further modifications. The proposed SVM (DTAK-SVM) is evaluated in speaker-dependent speech recognition experiments of hand-segmented phoneme recognition. Preliminary experimental results show comparable recognition performance with hidden Markov models (HMMs).

We present an information-geometric measure to systematically investigate neuronal firing patterns, taking account not only of the second-order but also of higher-order interactions. We begin with the case of two neurons for illustration and show how to test whether or not any pairwise correlation in one period is significantly different from that in the other period. In order to test such a hypothesis of different firing rates, the correlation term needs to be singled out'orthogonally' to the firing rates, where the null hypothesis might not be of independent firing. This method is also shown to directly associate neural firing with behavior via their mutual information, which is decomposed into two types of information, conveyed by mean firing rate and coincident firing, respectively. Then, we show that these results, using the'orthogonal' decomposition, are naturally extended to the case of three neurons and n neurons in general. 1 Introduction Based on the theory of hierarchical structure and related invariant decomposition of interactions by information geometry [3], the present paper briefly summarizes methods useful for systematically analyzing a population of neural firing [9].

We describe a neural network which enhances and completes salient closed contours. Our work is different from all previous work in three important ways. First, like the input provided to V1 by LGN, the input to our computation is isotropic. That is, the input is composed of spots not edges. Second, our network computes a well defined function of the input based on a distribution of closed contours characterized by a random process. Third, even though our computation is implemented in a discrete network, its output is invariant to continuous rotations and translations of the input pattern.

The support vector machine (SVM) is known for its good performance in binary classification, but its extension to multi-class classification is still an ongoing research issue. In this paper, we propose a new approach for classification, called the import vector machine (IVM), which is built on kernel logistic regression (KLR). We show that the IVM not only performs as well as the SVM in binary classification, but also can naturally be generalized to the multi-class case. Furthermore, the IVM provides an estimate of the underlying probability. Similar to the "support points" of the SVM, the IVM model uses only a fraction of the training data to index kernel basis functions, typically a much smaller fraction than the SVM. This gives the IVM a computational advantage over the SVM, especially when the size of the training data set is large.

An important issue in applying SVMs to speech recognition is the ability to classify variable length sequences. This paper presents extensions to a standard scheme for handling this variable length data, the Fisher score. A more useful mapping is introduced based on the likelihood-ratio. The score-space defined by this mapping avoids some limitations of the Fisher score. Class-conditional generative models are directly incorporated into the definition of the score-space.

When designing a two-alternative classifier, one ordinarily aims to maximize the classifier's ability to discriminate between members of the two classes. We describe a situation in a real-world business application of machine-learning prediction in which an additional constraint is placed on the nature of the solution: that the classifier achieve a specified correct acceptance or correct rejection rate (i.e., that it achieve a fixed accuracy on members of one class or the other). Our domain is predicting churn in the telecommunications industry. Churn refers to customers who switch from one service provider to another. We propose four algorithms for training a classifier subject to this domain constraint, and present results showing that each algorithm yields a reliable improvement in performance.