We consider the problem of grasping novel objects, specifically ones that are being seenfor the first time through vision. We present a learning algorithm that neither requires, nor tries to build, a 3d model of the object. Instead it predicts, directly as a function of the images, a point at which to grasp the object. Our algorithm istrained via supervised learning, using synthetic images for the training set. We demonstrate on a robotic manipulation platform that this approach successfully graspsa wide variety of objects, such as wine glasses, duct tape, markers, a translucent box, jugs, knife-cutters, cellphones, keys, screwdrivers, staplers, toothbrushes, a thick coil of wire, a strangely shaped power horn, and others, none of which were seen in the training set.

Although there has been substantial progress in understanding the neurophysiological mechanismsof stereopsis, how neurons interact in a network during stereo computation remains unclear. Computational models on stereopsis suggest local competition and long-range cooperation are important forresolving ambiguity during stereo matching. To test these predictions, wesimultaneously recorded from multiple neurons in V1 of awake, behaving macaques while presenting surfaces of different depths rendered in dynamic random dot stereograms. We found that the interaction between pairs of neurons was a function of similarity in receptive fields, as well as of the input stimulus. Neurons coding the same depth experienced common inhibition early in their responses for stimuli presented at their nonpreferred disparities.They experienced mutual facilitation later in their responses for stimulation at their preferred disparity. These findings are consistent with a local competition mechanism that first removes gross mismatches, anda global cooperative mechanism that further refines depth estimates.

We describe Hidden Semi-Markov Support Vector Machines (SHM SVMs), an extension of HM SVMs to semi-Markov chains. This allows us to predict segmentations ofsequences based on segment-based features measuring properties such as the length of the segment. We propose a novel technique to partition the problem into sub-problems. The independently obtained partial solutions can then be recombined in an efficient way, which allows us to solve label sequence learning problemswith several thousands of labeled sequences. We have tested our algorithm for predicting gene structures, an important problem in computational biology. Results on a well-known model organism illustrate the great potential of SHM SVMs in computational biology.

The Maximum Margin Planning (MMP) (Ratliff et al., 2006) algorithm solves imitation learning problems by learning linear mappings from features to cost functions in a planning domain. The learned policy is the result of minimum-cost planning using these cost functions. These mappings are chosen so that example policies (or trajectories) given by a teacher appear to be lower cost (with a lossscaled margin)than any other policy for a given planning domain. We provide a novel approach, MMPBOOST, based on the functional gradient descent view of boosting (Mason et al., 1999; Friedman, 1999a) that extends MMP by "boosting" in new features. This approach uses simple binary classification or regression to improve performance of MMP imitation learning, and naturally extends to the class of structured maximum margin prediction problems.

Identification of Clusters is the most basic tool for data analysis and unsupervised learning.

Measurements from sensor systems typically serve as a proxy for latent variables of interest.

Bayesian inference has become increasingly important in statistical machine learning. Exact Bayesian calculations are often not feasible in practice, however. A number of approximate Bayesian methods have been proposed to make such calculations practical, among them the variational Bayesian (VB) approach. The VB approach, while useful, can nevertheless suffer from slow convergence to the approximate solution. To address this problem, we propose Parameter-eXpanded Variational Bayesian (PX-VB) methods to speed up VB. The new algorithm is inspired byparameter-expanded expectation maximization (PX-EM) and parameterexpanded dataaugmentation (PX-DA). Similar to PX-EM and -DA, PX-VB expands a model with auxiliary variables to reduce the coupling between variables in the original model. We analyze the convergence rates of VB and PX-VB and demonstrate the superior convergence rates of PX-VB in variational probit regression andautomatic relevance determination.

Image registration and super-resolution are often treated as distinct processes, to be considered sequentially [1, 3, 7]. Hardie et al. demonstrated that the low-resolution image registration can be

We develop and analyze game-theoretic algorithms for predicting coordinate binding ofmultiple DNA binding regulators. The allocation of proteins to local neighborhoods andto sites is carried out with resource constraints while explicating competing and coordinate binding relations among proteins with affinity to the site or region. The focus of this paper is on mathematical foundations of the approach. Wealso briefly demonstrate the approach in the context of the λ-phage switch.

Scoring structures of undirected graphical models by means of evaluating the marginal likelihood is very hard. The main reason is the presence of the partition functionwhich is intractable to evaluate, let alone integrate over. We propose to approximate the marginal likelihood by employing two levels of approximation: we assume normality of the posterior (the Laplace approximation) and approximate allremaining intractable quantities using belief propagation and the linear response approximation.