Semi-supervised regression based on the graph Laplacian suffers from the fact that the solution is biased towards a constant and the lack of extrapolating power. Outgoing from these observations we propose to use the second-order Hessian energy for semi-supervised regression which overcomes both of these problems, in particular, if the data lies on or close to a low-dimensional submanifold in the feature space, the Hessian energy prefers functions which vary ``linearly with respect to the natural parameters in the data. This property makes it also particularly suited for the task of semi-supervised dimensionality reduction where the goal is to find the natural parameters in the data based on a few labeled points. The experimental result suggest that our method is superior to semi-supervised regression using Laplacian regularization and standard supervised methods and is particularly suited for semi-supervised dimensionality reduction.

The discovery of causal relationships between a set of observed variables is a fundamental problem in science. For continuous-valued data linear acyclic causal models are often used because these models are well understood and there are well-known methods to fit them to data. In reality, of course, many causal relationships are more or less nonlinear, raising some doubts as to the applicability and usefulness of purely linear methods. In this contribution we show that in fact the basic linear framework can be generalized to nonlinear models with additive noise. In this extended framework, nonlinearities in the data-generating process are in fact a blessing rather than a curse, as they typically provide information on the underlying causal system and allow more aspects of the true data-generating mechanisms to be identified. In addition to theoretical results we show simulations and some simple real data experiments illustrating the identification power provided by nonlinearities.

Multi-class object learning and detection is a challenging problem due to the large number of object classes and their high visual variability. Specialized detectors usuallyexcel in performance, while joint representations optimize sharing and reduce inference time -- but are complex to train. Conveniently, sequential class learning cuts down training time by transferring existing knowledge to novel classes, but cannot fully exploit the shareability of features among object classes and might depend on ordering of classes during learning. In hierarchical frameworks theseissues have been little explored. In this paper, we provide a rigorous experimental analysis of various multiple object class learning strategies within a generative hierarchical framework. Specifically, we propose, evaluate and compare threeimportant types of multi-class learning: 1.) independent training of individual categories, 2.) joint training of classes, and 3.) sequential learning of classes. We explore and compare their computational behavior (space and time) and detection performance as a function of the number of learned object classes on several recognition datasets. We show that sequential training achieves the best tradeoff between inference and training times at a comparable detection performance andcould thus be used to learn the classes on a larger scale.

A classic debate in cognitive science revolves around understanding how children learn complex linguistic rules, such as those governing restrictions on verb alternations, without negative evidence. Traditionally, formal learnability arguments have been used to claim that such learning is impossible without the aid of innate language-specific knowledge. However, recently, researchers have shown that statistical models are capable of learning complex rules from only positive evidence. These two kinds of learnability analyses differ in their assumptions about the role of the distribution from which linguistic input is generated. The former analyses assume that learners seek to identify grammatical sentences in a way that is robust to the distribution from which the sentences are generated, analogous to discriminative approaches in machine learning. The latter assume that learners are trying to estimate a generative model, with sentences being sampled from that model. We show that these two learning approaches differ in their use of implicit negative evidence -- the absence of a sentence -- when learning verb alternations, and demonstrate that human learners can produce results consistent with the predictions of both approaches, depending on the context in which the learning problem is presented.

Probabilistic topic models are a popular tool for the unsupervised analysis of text, providing both a predictive model of future text and a latent topic representation of the corpus. Practitioners typically assume that the latent space is semantically meaningful. It is used to check models, summarize the corpus, and guide exploration ofits contents. However, whether the latent space is interpretable is in need of quantitative evaluation. In this paper, we present new quantitative methods for measuring semantic meaning in inferred topics. We back these measures with large-scale user studies, showing that they capture aspects of the model that are undetected by previous measures of model quality based on held-out likelihood. Surprisingly, topic models which perform better on held-out likelihood may infer less semantically meaningful topics.

Embeddings of probability measures into reproducing kernel Hilbert spaces have been proposed as a straightforward and practical means of representing and comparing probabilities.In particular, the distance between embeddings (the maximum mean discrepancy, or MMD) has several key advantages over many classical metrics on distributions, namely easy computability, fast convergence and low bias of finite sample estimates. An important requirement of the embedding RKHS is that it be characteristic: in this case, the MMD between two distributions is zero if and only if the distributions coincide. Three new results on the MMD are introduced inthe present study. First, it is established that MMD corresponds to the optimal risk of a kernel classifier, thus forming a natural link between the distance between distributions and their ease of classification. An important consequence is that a kernel must be characteristic to guarantee classifiability between distributions inthe RKHS.

We introduce the first temporal-difference learning algorithms that converge with smooth value function approximators, such as neural networks. Conventional temporal-difference (TD) methods, such as TD($\lambda$), Q-learning and Sarsa have been used successfully with function approximation in many applications. However, it is well known that off-policy sampling, as well as nonlinear function approximation, can cause these algorithms to become unstable (i.e., the parameters of the approximator may diverge). Sutton et al (2009a,b) solved the problem of off-policy learning with linear TD algorithms by introducing a new objective function, related to the Bellman-error, and algorithms that perform stochastic gradient-descent on this function. In this paper, we generalize their work to nonlinear function approximation. We present a Bellman error objective function and two gradient-descent TD algorithms that optimize it. We prove the asymptotic almost-sure convergence of both algorithms for any finite Markov decision process and any smooth value function approximator, under usual stochastic approximation conditions. The computational complexity per iteration scales linearly with the number of parameters of the approximator. The algorithms are incremental and are guaranteed to converge to locally optimal solutions.

In this paper, we address the question of what kind of knowledge is generally transferable from unlabeled text. We suggest and analyze the semantic correlation of words as a generally transferable structure of the language and propose a new method to learn this structure using an appropriately chosen latent variable model. This semantic correlation contains structural information of the language space and can be used to control the joint shrinkage of model parameters for any specific task in the same space through regularization. In an empirical study, we construct 190 different text classification tasks from a real-world benchmark, and the unlabeled documents are a mixture from all these tasks. We test the ability of various algorithms to use the mixed unlabeled text to enhance all classification tasks. Empirical results show that the proposed approach is a reliable and scalable method for semi-supervised learning, regardless of the source of unlabeled data, the specific task to be enhanced, and the prediction model used.

Statistical evolutionary models provide an important mechanism for describing and understanding the escape response of a viral population under a particular therapy. We present a new hierarchical model that incorporates spatially varying mutation and recombination rates at the nucleotide level. It also maintains sep- arate parameters for treatment and control groups, which allows us to estimate treatment effects explicitly. We use the model to investigate the sequence evolu- tion of HIV populations exposed to a recently developed antisense gene therapy, as well as a more conventional drug therapy. The detection of biologically rele- vant and plausible signals in both therapy studies demonstrates the effectiveness of the method.

In this work, we consider the problem of learning a positive semidefinite matrix. The critical issue is how to preserve positive semidefiniteness during the course of learning. Our algorithm is mainly inspired by LPBoost [1] and the general greedy convex optimization framework of Zhang [2]. We demonstrate the essence of the algorithm, termed PSDBoost (positive semidefinite Boosting), by focusing on a few different applications in machine learning. The proposed PSDBoost algorithm extends traditional Boosting algorithms in that its parameter is a positive semidefinite matrix with trace being one instead of a classifier. PSDBoost is based on the observation that any trace-one positive semidefinitematrix can be decomposed into linear convex combinations of trace-one rank-one matrices, which serve as base learners of PSDBoost. Numerical experiments are presented.