Probabilistic topic models are a popular tool for the unsupervised analysis of text, providing both a predictive model of future text and a latent topic representation of the corpus. Practitioners typically assume that the latent space is semantically meaningful. It is used to check models, summarize the corpus, and guide exploration ofits contents. However, whether the latent space is interpretable is in need of quantitative evaluation. In this paper, we present new quantitative methods for measuring semantic meaning in inferred topics. We back these measures with large-scale user studies, showing that they capture aspects of the model that are undetected by previous measures of model quality based on held-out likelihood. Surprisingly, topic models which perform better on held-out likelihood may infer less semantically meaningful topics.

In this study, we present a method for estimating the mutual information for a localized pattern of fMRI data. We show that taking a multivariate information approach to voxel selection leads to a decoding accuracy that surpasses an univariate inforamtion approach and other standard voxel selection methods. Furthermore,we extend the multivariate mutual information theory to measure the functional connectivity between distributed brain regions. By jointly estimating the information shared by two sets of voxels we can reliably map out the connectivities in the human brain during experiment conditions. We validated our approach on a 6-way scene categorization fMRI experiment. The multivariate information analysis is able to find strong information flow between PPA and RSC, which confirms existing neuroscience studies on scenes. Furthermore, by exploring over the whole brain, our method identifies other interesting ROIs that share information with the PPA, RSC scene network,suggesting interesting future work for neuroscientists.

We describe probability distributions, dubbed compressible priors, whose independent and identically distributed (iid) realizations result in compressible signals. A signal is compressible when sorted magnitudes of its coefficients exhibit a power-law decay so that the signal can be well-approximated by a sparse signal. Since compressible signals live close to sparse signals, their intrinsic information can be stably embedded via simple non-adaptive linear projections into a much lower dimensional space whose dimension grows logarithmically with the ambient signal dimension. By using order statistics, we show that N-sample iid realizations of generalized Pareto, Student’s t, log-normal, Frechet, and log-logistic distributions are compressible, i.e., they have a constant expected decay rate, which is independent of N. In contrast, we show that generalized Gaussian distribution with shape parameter q is compressible only in restricted cases since the expected decay rate of its N-sample iid realizations decreases with N as 1/[q log(N/q)]. We use compressible priors as a scaffold to build new iterative sparse signal recovery algorithms based on Bayesian inference arguments. We show how tuning of these algorithms explicitly depends on the parameters of the compressible prior of the signal, and how to learn the parameters of the signal’s compressible prior on the fly during recovery.

Schizophrenia is a complex psychiatric disorder that has eluded a characterization in terms of local abnormalities of brain activity, and is hypothesized to affect the collective, ``emergent working of the brain. We propose a novel data-driven approach to capture emergent features using functional brain networks [Eguiluzet al] extracted from fMRI data, and demonstrate its advantage over traditional region-of-interest (ROI) and local, task-specific linear activation analyzes. Our results suggest that schizophrenia is indeed associated with disruption of global, emergent brain properties related to its functioning as a network, which cannot be explained by alteration of local activation patterns. Moreover, further exploitation of interactions by sparse Markov Random Field classifiers shows clear gain over linear methods, such as Gaussian Naive Bayes and SVM, allowing to reach 86% accuracy (over 50% baseline - random guess), which is quite remarkable given that it is based on a single fMRI experiment using a simple auditory task.

Over recent years Dirichlet processes and the associated Chinese restaurant process (CRP) have found many applications in clustering while the Indian buffet process (IBP) is increasingly used to describe latent feature models. In the clustering case, we associate to each data point a latent allocation variable. These latent variables can share the same value and this induces a partition of the data set. The CRP is a prior distribution on such partitions. In latent feature models, we associate to each data point a potentially infinite number of binary latent variables indicating the possession of some features and the IBP is a prior distribution on the associated infinite binary matrix. These prior distributions are attractive because they ensure exchangeability (over samples). We propose here extensions of these models to decomposable graphs. These models have appealing properties and can be easily learned using Monte Carlo techniques.

We describe a new algorithmic framework for inference in probabilistic models, and apply it to inference for latent Dirichlet allocation. Our framework adopts the methodology of variational inference, but unlike existing variational methods such as mean field and expectation propagation it is not restricted to tractable classes of approximating distributions. Our approach can also be viewed as a sequential Monte Carlo (SMC) method, but unlike existing SMC methods there is no need to design the artificial sequence of distributions. Notably, our framework offers a principled means to exchange the variance of an importance sampling estimate for the bias incurred through variational approximation. Experiments on a challenging inference problem in population genetics demonstrate improvements in stability and accuracy over existing methods, and at a comparable cost.

Speaker comparison, the process of finding the speaker similarity between two speech signals, occupies a central role in a variety of applications---speaker verification, clustering, and identification. Speaker comparison can be placed in a geometric framework by casting the problem as a model comparison process. For a given speech signal, feature vectors are produced and used to adapt a Gaussian mixture model (GMM). Speaker comparison can then be viewed as the process of compensating and finding metrics on the space of adapted models. We propose a framework, inner product discriminant functions (IPDFs), which extends many common techniques for speaker comparison: support vector machines, joint factor analysis, and linear scoring. The framework uses inner products between the parameter vectors of GMM models motivated by several statistical methods. Compensation of nuisances is performed via linear transforms on GMM parameter vectors. Using the IPDF framework, we show that many current techniques are simple variations of each other. We demonstrate, on a 2006 NIST speaker recognition evaluation task, new scoring methods using IPDFs which produce excellent error rates and require significantly less computation than current techniques.

Interesting real-world datasets often exhibit nonlinear, noisy, continuous-valued states that are unexplorable, are poorly described by first principles, and are only partially observable. If partial observability can be overcome, these constraints suggest the use of model-based reinforcement learning. We experiment with manifold embeddings as the reconstructed observable state-space of an off-line, model-based reinforcement learning approach to control. We demonstrate the embedding of a system changes as a result of learning and that the best performing embeddings well-represent the dynamics of both the uncontrolled and adaptively controlled system. We apply this approach in simulation to learn a neurostimulation policy that is more efficient in treating epilepsy than conventional policies. We then demonstrate the learned policy completely suppressing seizures in real-world neurostimulation experiments on actual animal brain slices.

The standard assumption of identically distributed training and test data can be violated when an adversary can exercise some control over the generation of the test data. In a prediction game, a learner produces a predictive model while an adversary may alter the distribution of input data. We study single-shot prediction games in which the cost functions of learner and adversary are not necessarily antagonistic. We identify conditions under which the prediction game has a unique Nash equilibrium, and derive algorithms that will find the equilibrial prediction models. In a case study, we explore properties of Nash-equilibrial prediction models for email spam filtering empirically.

A goal of central importance in the study of hierarchical models for object recognition -- and indeed the visual cortex -- is that of understanding quantitatively the trade-off between invariance and selectivity, and how invariance and discrimination properties contribute towards providing an improved representation useful for learning from data. In this work we provide a general group-theoretic framework for characterizing and understanding invariance in a family of hierarchical models. We show that by taking an algebraic perspective, one can provide a concise set of conditions which must be met to establish invariance, as well as a constructive prescription for meeting those conditions. Analyses in specific cases of particular relevance to computer vision and text processing are given, yielding insight into how and when invariance can be achieved. We find that the minimal sets of transformations intrinsic to the hierarchical model needed to support a particular invariance can be clearly described, thereby encouraging efficient computational implementations.