Neural responses in visual cortex are influenced by visual stimuli and by ongoing spiking activity in local circuits. An important challenge in computational neuroscience is to develop models that can account for both of these features in large multi-neuron recordings and to reveal how stimulus representations interact with and depend on cortical dynamics. Here we introduce a statistical model of neural population activity that integrates a nonlinear receptive field model with a latent dynamical model of ongoing cortical activity. This model captures the temporal dynamics, effective network connectivity in large population recordings, and correlations due to shared stimulus drive as well as common noise. Moreover, because the nonlinear stimulus inputs are mixed by the ongoing dynamics, the model can account for a relatively large number of idiosyncratic receptive field shapes with a small number of nonlinear inputs to a low-dimensional latent dynamical model. We introduce a fast estimation method using online expectation maximization with Laplace approximations. Inference scales linearly in both population size and recording duration. We apply this model to multi-channel recordings from primary visual cortex and show that it accounts for a large number of individual neural receptive fields using a small number of nonlinear inputs and a low-dimensional dynamical model.

We study online combinatorial decision problems, where one must make sequential decisions in some combinatorial space without knowing in advance the cost of decisions on each trial; the goal is to minimize the total regret over some sequence of trials relative to the best fixed decision in hindsight. Such problems have been studied mostly in settings where decisions are represented by Boolean vectors and costs are linear in this representation. Here we study a general setting where costs may be linear in any suitable low-dimensional vector representation of elements of the decision space. We give a general algorithm for such problems that we call low-dimensional online mirror descent (LDOMD); the algorithm generalizes both the Component Hedge algorithm of Koolen et al. (2010), and a recent algorithm of Suehiro et al. (2012). Our study offers a unification and generalization of previous work, and emphasizes the role of the convex polytope arising from the vector representation of the decision space; while Boolean representations lead to 0-1 polytopes, more general vector representations lead to more general polytopes. We study several examples of both types of polytopes. Finally, we demonstrate the benefit of having a general framework for such problems via an application to an online transportation problem; the associated transportation polytopes generalize the Birkhoff polytope of doubly stochastic matrices, and the resulting algorithm generalizes the PermELearn algorithm of Helmbold and Warmuth (2009).

The brain uses population codes to form distributed, noise-tolerant representations of sensory and motor variables. Recent work has examined the theoretical optimality of such codes in order to gain insight into the principles governing population codes found in the brain. However, the majority of the population coding literature considers either conditionally independent neurons or neurons with noise governed by a stimulus-independent covariance matrix. Here we analyze population coding under a simple alternative model in which latent input noise" corrupts the stimulus before it is encoded by the population. This provides a convenient and tractable description for irreducible uncertainty that cannot be overcome by adding neurons, and induces stimulus-dependent correlations that mimic certain aspects of the correlations observed in real populations. We examine prior-dependent, Bayesian optimal coding in such populations using exact analyses of cases in which the posterior is approximately Gaussian. These analyses extend previous results on independent Poisson population codes and yield an analytic expression for squared loss and a tight upper bound for mutual information. We show that, for homogeneous populations that tile the input domain, optimal tuning curve width depends on the prior, the loss function, the resource constraint, and the amount of input noise. This framework provides a practical testbed for examining issues of optimality, noise, correlation, and coding fidelity in realistic neural populations."

This paper proposes a new hybrid architecture that consists of a deep Convolutional Network and a Markov Random Field. We show how this architecture is successfully applied to the challenging problem of articulated human pose estimation in monocular images. The architecture can exploit structural domain constraints such as geometric relationships between body joint locations. We show that joint training of these two model paradigms improves performance and allows us to significantly outperform existing state-of-the-art techniques.

In many situations we have some measurement of confidence on ``positiveness for a binary label. The ``positiveness" is a continuous value whose range is a bounded interval. It quantifies the affiliation of each training data to the positive class. We propose a novel learning algorithm called \emph{expectation loss SVM} (e-SVM) that is devoted to the problems where only the ``positiveness" instead of a binary label of each training sample is available. Our e-SVM algorithm can also be readily extended to learn segment classifiers under weak supervision where the exact positiveness value of each training example is unobserved. In experiments, we show that the e-SVM algorithm can effectively address the segment proposal classification task under both strong supervision (e.g. the pixel-level annotations are available) and the weak supervision (e.g. only bounding-box annotations are available), and outperforms the alternative approaches. Besides, we further validate this method on two major tasks of computer vision: semantic segmentation and object detection. Our method achieves the state-of-the-art object detection performance on PASCAL VOC 2007 dataset."

While topic models can discover patterns of word usage in large corpora, it is difficult to meld this unsupervised structure with noisy, human-provided labels, especially when the label space is large. In this paper, we present a model-Label to Hierarchy (L2H)-that can induce a hierarchy of user-generated labels and the topics associated with those labels from a set of multi-labeled documents. The model is robust enough to account for missing labels from untrained, disparate annotators and provide an interpretable summary of an otherwise unwieldy label set. We show empirically the effectiveness of L2H in predicting held-out words and labels for unseen documents.

A central result in statistical theory is Pinsker's theorem, which characterizes the minimax rate in the normal means model of nonparametric estimation. In this paper, we present an extension to Pinsker's theorem where estimation is carried out under storage or communication constraints. In particular, we place limits on the number of bits used to encode an estimator, and analyze the excess risk in terms of this constraint, the signal size, and the noise level. We give sharp upper and lower bounds for the case of a Euclidean ball, which establishes the Pareto-optimal minimax tradeoff between storage and risk in this setting.

Blind source separation problems are difficult because they are inherently unidentifiable, yet the entire goal is to identify meaningful sources. We introduce a way of incorporating domain knowledge into this problem, called signal aggregate constraints (SACs). SACs encourage the total signal for each of the unknown sources to be close to a specified value. This is based on the observation that the total signal often varies widely across the unknown sources, and we often have a good idea of what total values to expect. We incorporate SACs into an additive factorial hidden Markov model (AFHMM) to formulate the energy disaggregation problems where only one mixture signal is assumed to be observed. A convex quadratic program for approximate inference is employed for recovering those source signals. On a real-world energy disaggregation data set, we show that the use of SACs dramatically improves the original AFHMM, and significantly improves over a recent state-of-the art approach.

A predictor that is deployed in a live production system may perturb the features it uses to make predictions. Such a feedback loop can occur, for example, when a model that predicts a certain type of behavior ends up causing the behavior it predicts, thus creating a self-fulfilling prophecy. In this paper we analyze predictor feedback detection as a causal inference problem, and introduce a local randomization scheme that can be used to detect non-linear feedback in real-world problems. We conduct a pilot study for our proposed methodology using a predictive system currently deployed as a part of a search engine.

We formulate the problem of metric learning for k nearest neighbor classification as a large margin structured prediction problem, with a latent variable representing the choice of neighbors and the task loss directly corresponding to classification error. We describe an efficient algorithm for exact loss augmented inference, and a fast gradient descent algorithm for learning in this model. The objective drives the metric to establish neighborhood boundaries that benefit the true class labels for the training points. Our approach, reminiscent of gerrymandering (redrawing of political boundaries to provide advantage to certain parties), is more direct in its handling of optimizing classification accuracy than those previously proposed. In experiments on a variety of data sets our method is shown to achieve excellent results compared to current state of the art in metric learning.