Digital histology images are amenable to the application of convolutional neural network (CNN) for analysis due to the sheer size of pixel data present in them. CNNs are generally used for representation learning from small image patches (e.g. 224x224) extracted from digital histology images due to computational and memory constraints. However, this approach does not incorporate high-resolution contextual information in histology images. We propose a novel way to incorporate larger context by a context-aware neural network based on images with a dimension of 1,792x1,792 pixels. The proposed framework first encodes the local representation of a histology image into high dimensional features then aggregates the features by considering their spatial organization to make a final prediction. The proposed method is evaluated for colorectal cancer grading and breast cancer classification. A comprehensive analysis of some variants of the proposed method is presented. Our method outperformed the traditional patch-based approaches, problem-specific methods, and existing context-based methods quantitatively by a margin of 3.61%. Code and dataset related information is available at this link: https://tia-lab.github.io/Context-Aware-CNN

Background: Palliative care is referred to a set of programs for patients that suffer life-limiting illnesses. These programs aim to guarantee a minimum level of quality of life (QoL) for the last stage of life. They are currently based on clinical evaluation of risk of one-year mortality. Objectives: The main objective of this work is to develop and validate machine-learning based models to predict the exitus of a patient within the next year using data gathered at hospital admission. Methods: Five machine learning techniques were applied in our study to develop machine-learning predictive models: Support Vector Machines, K-neighbors Classifier, Gradient Boosting Classifier, Random Forest and Multilayer Perceptron. All models were trained and evaluated using the retrospective dataset. The evaluation was performed with five metrics computed by a resampling strategy: Accuracy, the area under the ROC curve, Specificity, Sensitivity, and the Balanced Error Rate. Results: All models for forecasting one-year mortality achieved an AUC ROC from 0.858 to 0.911. Specifically, Gradient Boosting Classifier was the best model, producing an AUC ROC of 0.911 (CI 95%, 0.911 to 0.912), a sensitivity of 0.858 (CI 95%, 0.856 to 0.86) and a specificity of 0.807 (CI 95%, 0.806 to 0808) and a BER of 0.168 (CI 95%, 0.167 to 0.169). Conclusions: The analysis of common information at hospital admission combined with machine learning techniques produced models with competitive discriminative power. Our models reach the best results reported in state of the art. These results demonstrate that they can be used as an accurate data-driven palliative care criteria inclusion.

Decentralized training of deep learning models is a key element for enabling data privacy and on-device learning over networks, as well as for efficient scaling to large compute clusters. As current approaches suffer from limited bandwidth of the network, we propose the use of communication compression in the decentralized training context. We show that Choco-SGD $-$ recently introduced and analyzed for strongly-convex objectives only $-$ converges under arbitrary high compression ratio on general non-convex functions at the rate $O\bigl(1/\sqrt{nT}\bigr)$ where $T$ denotes the number of iterations and $n$ the number of workers. The algorithm achieves linear speedup in the number of workers and supports higher compression than previous state-of-the art methods. We demonstrate the practical performance of the algorithm in two key scenarios: the training of deep learning models (i) over distributed user devices, connected by a social network and (ii) in a datacenter (outperforming all-reduce time-wise).

A Markov Decision Process (MDP) is a popular model for reinforcement learning. However, its commonly used assumption of stationary dynamics and rewards is too stringent and fails to hold in adversarial, nonstationary, or multi-agent problems. We study an episodic setting where the parameters of an MDP can differ across episodes. We learn a reliable policy of this potentially adversarial MDP by developing an Adversarial Reinforcement Learning (ARL) algorithm that reduces our MDP to a sequence of \emph{adversarial} bandit problems. ARL achieves $O(\sqrt{SATH^3})$ regret, which is optimal with respect to $S$, $A$, and $T$, and its dependence on $H$ is the best (even for the usual stationary MDP) among existing model-free methods.

Management and efficient operations in critical infrastructure such as Smart Grids take huge advantage of accurate power load forecasting which, due to its nonlinear nature, remains a challenging task. Recently, deep learning has emerged in the machine learning field achieving impressive performance in a vast range of tasks, from image classification to machine translation. Applications of deep learning models to the electric load forecasting problem are gaining interest among researchers as well as the industry, but a comprehensive and sound comparison among different architectures is not yet available in the literature. This work aims at filling the gap by reviewing and experimentally evaluating on two real-world datasets the most recent trends in electric load forecasting, by contrasting deep learning architectures on short term forecast (one day ahead prediction). Specifically, we focus on feedforward and recurrent neural networks, sequence to sequence models and temporal convolutional neural networks along with architectural variants, which are known in the signal processing community but are novel to the load forecasting one.

The failure of a complex and safety critical industrial asset can have extremely high consequences. Close monitoring for early detection of abnormal system conditions is therefore required. Data-driven solutions to this problem have been limited for two reasons: First, safety critical assets are designed and maintained to be highly reliable and faults are rare. Fault detection can thus not be supervised. Second, complex industrial systems usually have long lifetime and face very different operating conditions. Collecting a representative training dataset would require long observation periods, and delay the monitoring of the system. In this paper, we propose a methodology to monitor the systems in their early life. To do so, we enhance the training dataset with other units from a fleet, for which longer observations are available. Since each unit has its own specificity, we propose to extract features made independent of their origin by three unsupervised feature alignment techniques. First, using a variational encoder, we impose a shared latent space for both units. Second, we introduce a new loss designed to conserve inter-point spacial relationships between the input and the latent spaces. Last, we propose to train in an adversarial manner a discriminator on the origin of the features. Once aligned, the features are fed to a one-class classifier to monitor the health of the system. By exploring the different combinations of the proposed alignment strategies, and by testing them on a real case study, a fleet composed of 112 power plants operated in different geographical locations and under very different operating regimes, we demonstrate that this alignment is necessary and beneficial.

The OGY method is one of control methods for a chaotic system. In the method, we have to calculate a stabilizing periodic orbit embedded in its chaotic attractor. Thus, we cannot use this method in the case where a precise mathematical model of the chaotic system cannot be identified. In this case, the delayed feedback control proposed by Pyragas is useful. However, even in the delayed feedback control, we need the mathematical model to determine a feedback gain that stabilizes the periodic orbit. To overcome this problem, we propose a model-free reinforcement learning algorithm to the design of a controller for the chaotic system. In recent years, model-free reinforcement learning algorithms with deep neural networks have been paid much attention to. Those algorithms make it possible to control complex systems. However, it is known that model-free reinforcement learning algorithms are not efficient because learners must explore their control policies over the entire state space. Moreover, model-free reinforcement learning algorithms with deep neural networks have the disadvantage in taking much time to learn their control optimal policies. Thus, we propose a data-based control policy consisting of two steps, where we determine a region including the stabilizing periodic orbit first, and make the controller learn an optimal control policy for its stabilization. In the proposed method, the controller efficiently explores its control policy only in the region.

Question answering has emerged as an intuitive way of querying structured data sources, and has attracted significant advancements over the years. In this article, we provide an overview over these recent advancements, focusing on neural network based question answering systems over knowledge graphs. We introduce readers to the challenges in the tasks, current paradigms of approaches, discuss notable advancements, and outline the emerging trends in the field. Through this article, we aim to provide newcomers to the field with a suitable entry point, and ease their process of making informed decisions while creating their own QA system.

Vehicle-to-vehicle (V2V) communications have distinct challenges that need to be taken into account when scheduling the radio resources. Although centralized schedulers (e.g., located on base stations) could be utilized to deliver high scheduling performance, they cannot be employed in case of coverage gaps. To address the issue of reliable scheduling of V2V transmissions out of coverage, we propose Vehicular Reinforcement Learning Scheduler (VRLS), a centralized scheduler that predictively assigns the resources for V2V communication while the vehicle is still in cellular network coverage. VRLS is a unified reinforcement learning (RL) solution, wherein the learning agent, the state representation, and the reward provided to the agent are applicable to different vehicular environments of interest (in terms of vehicular density, resource configuration, and wireless channel conditions). Such a unified solution eliminates the necessity of redesigning the RL components for a different environment, and facilitates transfer learning from one to another similar environment. We evaluate the performance of VRLS and show its ability to avoid collisions and half-duplex errors, and to reuse the resources better than the state of the art scheduling algorithms. We also show that pre-trained VRLS agent can adapt to different V2V environments with limited retraining, thus enabling real-world deployment in different scenarios.

Post-hoc interpretability approaches have been proven to be powerful tools to generate explanations for the predictions made by a trained black-box model. However, they create the risk of having explanations that are a result of some artifacts learned by the model instead of actual knowledge from the data. This paper focuses on the case of counterfactual explanations and asks whether the generated instances can be justified, i.e. continuously connected to some ground-truth data. We evaluate the risk of generating unjustified counterfactual examples by investigating the local neighborhoods of instances whose predictions are to be explained and show that this risk is quite high for several datasets. Furthermore, we show that most state of the art approaches do not differentiate justified from unjustified counterfactual examples, leading to less useful explanations.