Learning linear combinations of multiple kernels is an appealing strategy when the right choice of features is unknown. Previous approaches to multiple kernel learning (MKL) promote sparse kernel combinations and hence support interpretability. Unfortunately, L1-norm MKL is hardly observed to outperform trivial baselines in practical applications. To allow for robust kernel mixtures, we generalize MKL to arbitrary Lp-norms. We devise new insights on the connection between several existing MKL formulations and develop two efficient interleaved optimization strategies for arbitrary p>1. Empirically, we demonstrate that the interleaved optimization strategies are much faster compared to the traditionally used wrapper approaches. Finally, we apply Lp-norm MKL to real-world problems from computational biology, showing that non-sparse MKL achieves accuracies that go beyond the state-of-the-art.

Orthogonal matching pursuit (OMP) is a widely used greedy algorithm for recovering sparse vectors from linear measurements. A well-known analysis of Tropp and Gilbert shows that OMP can recover a k-sparse n-dimensional real vector from m = 4k log(n) noise-free random linear measurements with a probability that goes to one as n goes to infinity. This work shows strengthens this result by showing that a lower number of measurements, m = 2k log(n-k), is in fact sufficient for asymptotic recovery. Moreover, this number of measurements is also sufficient for detection of the sparsity pattern (support) of the vector with measurement errors provided the signal-to-noise ratio (SNR) scales to infinity. The scaling m = 2k log(n-k) exactly matches the number of measurements required by the more complex lasso for signal recovery.

Imaging techniques such as optical imaging of intrinsic signals, 2-photon calcium imaging and voltage sensitive dye imaging can be used to measure the functional organization of visual cortex across different spatial scales. Here, we present Bayesian methods based on Gaussian processes for extracting topographic maps from functional imaging data. In particular, we focus on the estimation of orientation preference maps (OPMs) from intrinsic signal imaging data. We model the underlying map as a bivariate Gaussian process, with a prior covariance function that reflects known properties of OPMs, and a noise covariance adjusted to the data. The posterior mean can be interpreted as an optimally smoothed estimate of the map, and can be used for model based interpolations of the map from sparse measurements. By sampling from the posterior distribution, we can get error bars on statistical properties such as preferred orientations, pinwheel locations or -counts. Finally, the use of an explicit probabilistic model facilitates interpretation of parameters and provides the basis for decoding studies. We demonstrate our model both on simulated data and on intrinsic signaling data from ferret visual cortex.

We develop a convex relaxation of maximum a posteriori estimation of a mixture of regression models. Although our relaxation involves a semidefinite matrix variable, we reformulate the problem to eliminate the need for general semidefinite programming. In particular, we provide two reformulations that admit fast algorithms. The first is a max-min spectral reformulation exploiting quasi-Newton descent. The second is a min-min reformulation consisting of fast alternating steps of closed-form updates. We evaluate the methods against Expectation-Maximization in a real problem of motion segmentation from video data.

Graph clustering methods such as spectral clustering are defined for general weighted graphs. In machine learning, however, data often is not given in form of a graph, but in terms of similarity (or distance) values between points. In this case, first a neighborhood graph is constructed using the similarities between the points and then a graph clustering algorithm is applied to this graph.

With the advent of the Internet it is now possible to collect hundreds of millions of images. These images come with varying degrees of label information. ``Clean labels can be manually obtained on a small fraction, ``noisy labels may be extracted automatically from surrounding text, while for most images there are no labels at all. Semi-supervised learning is a principled framework for combining these different label sources. However, it scales polynomially with the number of images, making it impractical for use on gigantic collections with hundreds of millions of images and thousands of classes. In this paper we show how to utilize recent results in machine learning to obtain highly efficient approximations for semi-supervised learning that are linear in the number of images.  Specifically, we use the convergence of the eigenvectors of the normalized graph Laplacian to eigenfunctions of weighted Laplace-Beltrami operators. We combine this with a label sharing framework obtained from Wordnet to propagate label information to classes lacking manual annotations. Our algorithm enables us to apply semi-supervised learning to a database of 80 million images with 74 thousand classes.

We propose a novel application of Formal Concept Analysis (FCA) to neural decoding: insteadof just trying to figure out which stimulus was presented, we demonstrate how to explore the semantic relationships in the neural representation of large sets of stimuli. FCA provides a way of displaying and interpreting such relationships via concept lattices. We explore the effects of neural code sparsity on the lattice. We then analyze neurophysiological data from high-level visual cortical areaSTSa, using an exact Bayesian approach to construct the formal context needed by FCA. Prominent features of the resulting concept lattices are discussed, including hierarchical face representation and indications for a product-of-experts code in real neurons.

We present a new co-clustering problem of images and visual features. The problem involvesa set of non-object images in addition to a set of object images and features to be co-clustered. Co-clustering is performed in a way that maximises discrimination of object images from non-object images, thus emphasizing discriminative features.This provides a way of obtaining perceptual joint-clusters of object images and features. We tackle the problem by simultaneously boosting multiplestrong classifiers which compete for images by their expertise. Each boosting classifier is an aggregation of weak-learners, i.e. simple visual features. The obtained classifiers are useful for object detection tasks which exhibit multimodalities, e.g.multi-category and multi-view object detection tasks. Experiments on a set of pedestrian images and a face data set demonstrate that the method yields intuitive image clusters with associated features and is much superior toconventional boosting classifiers in object detection tasks.

In a variety of behavioral tasks, subjects exhibit an automatic and apparently sub-optimal sequential effect: they respond more rapidly and accurately to a stimulus if it reinforces a local pattern in stimulus history, such as a string of repetitions or alternations, compared to when it violates such a pattern. This is often the case even if the local trends arise by chance in the context of a randomized design, such that stimulus history has no predictive power. In this work, we use a normative Bayesian framework to examine the hypothesis that such idiosyncrasies may reflect the inadvertent engagement of fundamental mechanisms critical for adapting to changing statistics in the natural environment. We show that prior belief in non-stationarity can induce experimentally observed sequential effects in an otherwise Bayes-optimal algorithm. The Bayesian algorithm is shown to be well approximated by linear-exponential filtering of past observations, a feature also apparent in the behavioral data. We derive an explicit relationship between the parameters and computations of the exact Bayesian algorithm and those of the approximate linear-exponential filter. Since the latter is equivalent to a leaky-integration process, a commonly used model of neuronal dynamics underlying perceptual decision-making and trial-to-trial dependencies, our model provides a principled account of why such dynamics are useful. We also show that near-optimal tuning of the leaky-integration process is possible, using stochastic gradient descent based only on the noisy binary inputs. This is a proof of concept that not only can neurons implement near-optimal prediction based on standard neuronal dynamics, but that they can also learn to tune the processing parameters without explicitly representing probabilities.

We formulate and address the problem of discovering dynamic malicious regions on the Internet. We model this problem as one of adaptively pruning a known decision tree, but with additional challenges: (1) severe space requirements, since the underlying decision tree has over 4 billion leaves, and (2) a changing target function, since malicious activity on the Internet is dynamic. We present a novel algorithm that addresses this problem, by putting together a number of different ``experts algorithms and online paging algorithms. We prove guarantees on our algorithms performance as a function of the best possible pruning of a similar size, and our experiments show that our algorithm achieves high accuracy on large real-world data sets, with significant improvements over existing approaches.