In this work, we present an approach to minimizing the time necessary for the end-effector of a redundant robot manipulator to traverse a Cartesian path by optimizing the trajectory of its joints. Each joint has limits in the ranges of position, velocity and acceleration, the latter making jerks in joint space undesirable. The proposed approach takes this nonlinear optimization problem whose variables are path speed and joint trajectory and reformulates it into a bi-level problem. The lower-level formulation is a convex subproblem that considers a fixed joint trajectory and maximizes path speed while considering all joint velocity and acceleration constraints. Under particular conditions, this subproblem has a closed-form solution. Then, we solve a higher-level subproblem by leveraging the directional derivative of the lower-level value with respect to the joint trajectory parameters. In particular, we use this direction to implement a Primal-Dual method that considers the path accuracy and joint position constraints. We show the efficacy of our proposed approach with simulations and experimental results.

Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these diverse series to form a coherent analysis presents significant challenges, such as differing spatial resolutions and contrast patterns meanwhile requiring extensive annotated data, which is scarce in clinical practice. Due to these issues, we introduce a novel Cross-Series Masking (CSM) Strategy for effectively learning MRI representation in a self-supervised manner. Specifically, CSM commences by randomly sampling a subset of regions and series, which are then strategically masked. In the training process, the cross-series representation is learned by utilizing the unmasked data to reconstruct the masked portions. This process not only integrates information across different series but also facilitates the ability to model both intra-series and inter-series correlations and complementarities. With the learned representation, the downstream tasks like segmentation and classification are also enhanced. Taking brain tissue segmentation, breast tumor benign/malignant classification, and prostate cancer diagnosis as examples, our method achieves state-of-the-art performance on both public and in-house datasets.

Students are increasingly relying on Generative AI (GAI) to support their writing-a key pedagogical practice in education. In GAI-assisted writing, students can delegate core cognitive tasks (e.g., generating ideas and turning them into sentences) to GAI while still producing high-quality essays. This creates new challenges for teachers in assessing and supporting student learning, as they often lack insight into whether students are engaging in meaningful cognitive processes during writing or how much of the essay's quality can be attributed to those processes. This study aimed to help teachers better assess and support student learning in GAI-assisted writing by examining how different writing behaviors, especially those indicative of meaningful learning versus those that are not, impact essay quality. Using a dataset of 1,445 GAI-assisted writing sessions, we applied the cutting-edge method, X-Learner, to quantify the causal impact of three GAI-assisted writing behavioral patterns (i.e., seeking suggestions but not accepting them, seeking suggestions and accepting them as they are, and seeking suggestions and accepting them with modification) on four measures of essay quality (i.e., lexical sophistication, syntactic complexity, text cohesion, and linguistic bias). Our analysis showed that writers who frequently modified GAI-generated text-suggesting active engagement in higher-order cognitive processes-consistently improved the quality of their essays in terms of lexical sophistication, syntactic complexity, and text cohesion. In contrast, those who often accepted GAI-generated text without changes, primarily engaging in lower-order processes, saw a decrease in essay quality. Additionally, while human writers tend to introduce linguistic bias when writing independently, incorporating GAI-generated text-even without modification-can help mitigate this bias.

In implicit emotion analysis (IEA), the subtlety of emotional expressions makes it particularly sensitive to user-specific characteristics. Existing studies often inject personalization into the analysis by focusing on the authorial dimension of the emotional text. However, these methods overlook the potential influence of the intended reader on the reaction of implicit emotions. In this paper, we refine the IEA task to Personalized Implicit Emotion Analysis (PIEA) and introduce the RAPPIE model, a novel framework designed to address the issue of missing user information within this task. In particular, 1) we create reader agents based on the Large Language Model to simulate reader reactions, to address challenges of the spiral of silence and data incompleteness encountered when acquiring reader feedback information. 2) We establish a reader propagation role system and develop a role-aware emotion propagation multi-view graph learning model, which effectively deals with the sparsity of reader information by utilizing the distribution of propagation roles. 3) We annotate two Chinese PIEA datasets with detailed user metadata, thereby addressing the limitation of prior datasets that primarily focus on textual content annotation. Extensive experiments on these datasets indicate that the RAPPIE model outperforms current state-of-the-art baselines, highlighting the significance and efficacy of incorporating reader feedback into the PIEA process.

Fully automated self-driving laboratories are promising to enable high-throughput and large-scale scientific discovery by reducing repetitive labour. However, effective automation requires deep integration of laboratory knowledge, which is often unstructured, multimodal, and difficult to incorporate into current AI systems. This paper introduces the k-agents framework, designed to support experimentalists in organizing laboratory knowledge and automating experiments with agents. Our framework employs large language model-based agents to encapsulate laboratory knowledge including available laboratory operations and methods for analyzing experiment results. To automate experiments, we introduce execution agents that break multi-step experimental procedures into state machines, interact with other agents to execute each step and analyze the experiment results. The analyzed results are then utilized to drive state transitions, enabling closed-loop feedback control. To demonstrate its capabilities, we applied the agents to calibrate and operate a superconducting quantum processor, where they autonomously planned and executed experiments for hours, successfully producing and characterizing entangled quantum states at the level achieved by human scientists. Our knowledge-based agent system opens up new possibilities for managing laboratory knowledge and accelerating scientific discovery.

Software vendors often silently release security patches without providing sufficient advisories (e.g., Common Vulnerabilities and Exposures) or delayed updates via resources (e.g., National Vulnerability Database). Therefore, it has become crucial to detect these security patches to ensure secure software maintenance. However, existing methods face the following challenges: (1) They primarily focus on the information within the patches themselves, overlooking the complex dependencies in the repository. (2) Security patches typically involve multiple functions and files, increasing the difficulty in well learning the representations. To alleviate the above challenges, this paper proposes a Repository-level Security Patch Detection framework named RepoSPD, which comprises three key components: 1) a repository-level graph construction, RepoCPG, which represents software patches by merging pre-patch and post-patch source code at the repository level; 2) a structure-aware patch representation, which fuses the graph and sequence branch and aims at comprehending the relationship among multiple code changes; 3) progressive learning, which facilitates the model in balancing semantic and structural information. To evaluate RepoSPD, we employ two widely-used datasets in security patch detection: SPI-DB and PatchDB. We further extend these datasets to the repository level, incorporating a total of 20,238 and 28,781 versions of repository in C/C++ programming languages, respectively, denoted as SPI-DB* and PatchDB*. We compare RepoSPD with six existing security patch detection methods and five static tools. Our experimental results demonstrate that RepoSPD outperforms the state-of-the-art baseline, with improvements of 11.90%, and 3.10% in terms of accuracy on the two datasets, respectively.

The hearing-impaired community in India deserves the access to tools that help them communicate, however, there is limited known technology solutions that make use of Indian Sign Language (ISL) at present. Even though there are many ISL users, ISL cannot access social and education arenas because there is not yet an efficient technology to convert the ISL signal into speech or text. We initiated this initiative owing to the rising demand for products and technologies that are inclusive and help ISL, filling the gap of communication for the ones with hearing disability. Our goal is to build an reliable sign language recognition system with the help of Convolutional Neural Networks (CNN) to . By expanding communication access, we aspire toward better educational opportunities and a more inclusive society for hearing impaired people in India.

This paper introduces lateral thinking to implement System-2 reasoning capabilities in AI systems, focusing on anticipatory and causal reasoning under uncertainty. We present a framework for systematic generation and modeling of lateral thinking queries and evaluation datasets. We introduce Streaming Agentic Lateral Thinking (SALT), a multi-agent framework designed to process complex, low-specificity queries in streaming data environments. SALT implements lateral thinking-inspired System-2 reasoning through a dynamic communication structure between specialized agents. Our key insight is that lateral information flow across long-distance agent interactions, combined with fine-grained belief management, yields richer information contexts and enhanced reasoning. Preliminary quantitative and qualitative evaluations indicate SALT's potential to outperform single-agent systems in handling complex lateral reasoning tasks in a streaming environment.

However, the existence of such capability transfer between natural language and gene sequences/languages remains under explored.This study addresses this gap by drawing inspiration from the sentence-pair classification task used for evaluating sentence similarity in natural language. We constructed two analogous tasks: DNA-pair classification(DNA sequence similarity) and DNA-protein-pair classification(gene coding determination). These tasks were designed to validate the transferability of capabilities from natural language to gene sequences. Even a small-scale pre-trained model like GPT-2-small, which was pre-trained on English, achieved an accuracy of 78% on the DNA-pair classification task after being fine-tuned on English sentence-pair classification data(XTREME PAWS-X). While training a BERT model on multilingual text, the precision reached 89%. On the more complex DNA-protein-pair classification task, however, the model's output was barely distinguishable from random output.Experimental validation has confirmed that the transfer of capabilities from natural language to biological language is unequivocally present. Building on this foundation, we have also investigated the impact of model parameter scale and pre-training on this capability transfer. We provide recommendations for facilitating the transfer of capabilities from natural language to genetic language,as well as new approaches for conducting biological research based on this capability.This study offers an intriguing new perspective on exploring the relationship between natural language and genetic language.

There has been extensive research on community detection in directed and bipartite networks. However, these studies often fail to consider the popularity of nodes in different communities, which is a common phenomenon in real-world networks. To address this issue, we propose a new probabilistic framework called the Two-Way Node Popularity Model (TNPM). The TNPM also accommodates edges from different distributions within a general sub-Gaussian family. We introduce the Delete-One-Method (DOM) for model fitting and community structure identification, and provide a comprehensive theoretical analysis with novel technical skills dealing with sub-Gaussian generalization. Additionally, we propose the Two-Stage Divided Cosine Algorithm (TSDC) to handle large-scale networks more efficiently. Our proposed methods offer multi-folded advantages in terms of estimation accuracy and computational efficiency, as demonstrated through extensive numerical studies. We apply our methods to two real-world applications, uncovering interesting findings.