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Tensor-based Multimodal Learning for Prediction of Pulmonary Arterial Wedge Pressure from Cardiac MRI

arXiv.org Artificial Intelligence

Heart failure is a serious and life-threatening condition that can lead to elevated pressure in the left ventricle. Pulmonary Arterial Wedge Pressure (PAWP) is an important surrogate marker indicating high pressure in the left ventricle. PAWP is determined by Right Heart Catheterization (RHC) but it is an invasive procedure. A non-invasive method is useful in quickly identifying high-risk patients from a large population. In this work, we develop a tensor learning-based pipeline for identifying PAWP from multimodal cardiac Magnetic Resonance Imaging (MRI). This pipeline extracts spatial and temporal features from high-dimensional scans. For quality control, we incorporate an epistemic uncertainty-based binning strategy to identify poor-quality training samples. To improve the performance, we learn complementary information by integrating features from multimodal data: cardiac MRI with short-axis and four-chamber views, and Electronic Health Records. The experimental analysis on a large cohort of $1346$ subjects who underwent the RHC procedure for PAWP estimation indicates that the proposed pipeline has a diagnostic value and can produce promising performance with significant improvement over the baseline in clinical practice (i.e., $\Delta$AUC $=0.10$, $\Delta$Accuracy $=0.06$, and $\Delta$MCC $=0.39$). The decision curve analysis further confirms the clinical utility of our method.


Automatically Identifying Relations Between Self-Admitted Technical Debt Across Different Sources

arXiv.org Artificial Intelligence

Self-Admitted Technical Debt or SATD can be found in various sources, such as source code comments, commit messages, issue tracking systems, and pull requests. Previous research has established the existence of relations between SATD items in different sources; such relations can be useful for investigating and improving SATD management. However, there is currently a lack of approaches for automatically detecting these SATD relations. To address this, we proposed and evaluated approaches for automatically identifying SATD relations across different sources. Our findings show that our approach outperforms baseline approaches by a large margin, achieving an average F1-score of 0.829 in identifying relations between SATD items. Moreover, we explored the characteristics of SATD relations in 103 open-source projects and describe nine major cases in which related SATD is documented in a second source, and give a quantitative overview of 26 kinds of relations.


Evolutionary quantum feature selection

arXiv.org Artificial Intelligence

Other study was realized by [5] that describes a variational quantum algorithm designed to solve unscontrained black box binary optimization problems, where the objective function Quantum Feature Selection (QFS) is a novel approach to is given as a black box. Unlike typical algorithms for optimization Feature Selection (FS) in Machine Learning (ML) that leverages where a classical objetive function is provided as a principles of Quantum Computing (QC) to enhance the Quandratic Uncontrained Binary Optimization problem and efficiency and effectiveness of traditional FS methods. The mapped toa sum of Pauli operators, this algorithm directly most informative features are typically selected in traditional handles the black box objective function. The algorithm s FS methods based on their correlation with the target variable theorical justification is based on convergence guarantees of or their predictive power. However, these methods can struggle quantum imaginary time evolution. The authors demonstrated with high-dimensional datasets, a phenomenon known as that the quantum method produced competitive, and in certain the curse of dimensionality [1]. On the other hand, Evolutionary aspects, even better perfomance compared to traditional FS Algorithms (EAs) are a family of optimization algorithms techniques used in today s industry. This suggests that quantum that are inspired by the process of natural selection and evolution.


EGFR mutation prediction using F18-FDG PET-CT based radiomics features in non-small cell lung cancer

arXiv.org Artificial Intelligence

Lung cancer is the leading cause of cancer death in the world. Accurate determination of the EGFR (epidermal growth factor receptor) mutation status is highly relevant for the proper treatment of this patients. Purpose: The aim of this study was to predict the mutational status of the EGFR in non-small cell lung cancer patients using radiomics features extracted from PET-CT images. Methods: Retrospective study that involve 34 patients with lung cancer confirmed by histology and EGFR status mutation assessment. A total of 2.205 radiomics features were extracted from manual segmentation of the PET-CT images using pyradiomics library. Both computed tomography and positron emission tomography images were used. All images were acquired with intravenous iodinated contrast and F18-FDG. Preprocessing includes resampling, normalization, and discretization of the pixel intensity. Three methods were used for the feature selection process: backward selection (set 1), forward selection (set 2), and feature importance analysis of random forest model (set 3). Nine machine learning methods were used for radiomics model building. Results: 35.2% of patients had EGFR mutation, without significant differences in age, gender, tumor size and SUVmax. After the feature selection process 6, 7 and 17 radiomics features were selected, respectively in each group. The best performances were obtained by Ridge Regression in set 1: AUC of 0.826 (95% CI, 0.811 - 0.839), Random Forest in set 2: AUC of 0.823 (95% CI, 0.808 - 0.838) and Neural Network in set 3: AUC of 0.821 (95% CI, 0.808 - 0.835). Conclusion: The radiomics features analysis has the potential of predicting clinically relevant mutations in lung cancer patients through a non-invasive methodology.


Symbolic Regression for PDEs using Pruned Differentiable Programs

arXiv.org Artificial Intelligence

Physics-informed Neural Networks (PINNs) have been widely used to obtain accurate neural surrogates for a system of Partial Differential Equations (PDE). One of the major limitations of PINNs is that the neural solutions are challenging to interpret, and are often treated as black-box solvers. While Symbolic Regression (SR) has been studied extensively, very few works exist which generate analytical expressions to directly perform SR for a system of PDEs. In this work, we introduce an end-to-end framework for obtaining mathematical expressions for solutions of PDEs. We use a trained PINN to generate a dataset, upon which we perform SR. We use a Differentiable Program Architecture (DPA) defined using context-free grammar to describe the space of symbolic expressions. We improve the interpretability by pruning the DPA in a depth-first manner using the magnitude of weights as our heuristic. On average, we observe a 95.3% reduction in parameters of DPA while maintaining accuracy at par with PINNs. Furthermore, on an average, pruning improves the accuracy of DPA by 7.81% . We demonstrate our framework outperforms the existing state-of-the-art SR solvers on systems of complex PDEs like Navier-Stokes: Kovasznay flow and Taylor-Green Vortex flow. Furthermore, we produce analytical expressions for a complex industrial use-case of an Air-Preheater, without suffering from performance loss viz-a-viz PINNs.


Domain Generalization in Machine Learning Models for Wireless Communications: Concepts, State-of-the-Art, and Open Issues

arXiv.org Artificial Intelligence

Data-driven machine learning (ML) is promoted as one potential technology to be used in next-generations wireless systems. This led to a large body of research work that applies ML techniques to solve problems in different layers of the wireless transmission link. However, most of these applications rely on supervised learning which assumes that the source (training) and target (test) data are independent and identically distributed (i.i.d). This assumption is often violated in the real world due to domain or distribution shifts between the source and the target data. Thus, it is important to ensure that these algorithms generalize to out-of-distribution (OOD) data. In this context, domain generalization (DG) tackles the OOD-related issues by learning models on different and distinct source domains/datasets with generalization capabilities to unseen new domains without additional finetuning. Motivated by the importance of DG requirements for wireless applications, we present a comprehensive overview of the recent developments in DG and the different sources of domain shift. We also summarize the existing DG methods and review their applications in selected wireless communication problems, and conclude with insights and open questions.


Scaling Vision-Language Models with Sparse Mixture of Experts

arXiv.org Artificial Intelligence

The field of natural language processing (NLP) has made significant strides in recent years, particularly in the development of large-scale vision-language models (VLMs). These models aim to bridge the gap between text and visual information, enabling a more comprehensive understanding of multimedia data. However, as these models become larger and more complex, they also become more challenging to train and deploy. One approach to addressing this challenge is the use of sparsely-gated mixture-of-experts (MoE) techniques, which divide the model into smaller, specialized sub-models that can jointly solve a task. In this paper, we explore the effectiveness of MoE in scaling vision-language models, demonstrating its potential to achieve state-of-the-art performance on a range of benchmarks over dense models of equivalent computational cost. Our research offers valuable insights into stabilizing the training of MoE models, understanding the impact of MoE on model interpretability, and balancing the trade-offs between compute performance when scaling VLMs. We hope our work will inspire further research into the use of MoE for scaling large-scale vision-language models and other multimodal machine learning applications.


Neural Transducer Training: Reduced Memory Consumption with Sample-wise Computation

arXiv.org Artificial Intelligence

The neural transducer is an end-to-end model for automatic speech recognition (ASR). While the model is well-suited for streaming ASR, the training process remains challenging. During training, the memory requirements may quickly exceed the capacity of state-of-the-art GPUs, limiting batch size and sequence lengths. In this work, we analyze the time and space complexity of a typical transducer training setup. We propose a memory-efficient training method that computes the transducer loss and gradients sample by sample. We present optimizations to increase the efficiency and parallelism of the sample-wise method. In a set of thorough benchmarks, we show that our sample-wise method significantly reduces memory usage, and performs at competitive speed when compared to the default batched computation. As a highlight, we manage to compute the transducer loss and gradients for a batch size of 1024, and audio length of 40 seconds, using only 6 GB of memory.


SegViz: A federated-learning based framework for multi-organ segmentation on heterogeneous data sets with partial annotations

arXiv.org Artificial Intelligence

Segmentation is one of the most primary tasks in deep learning for medical imaging, owing to its multiple downstream clinical applications. However, generating manual annotations for medical images is time-consuming, requires high skill, and is an expensive effort, especially for 3D images. One potential solution is to aggregate knowledge from partially annotated datasets from multiple groups to collaboratively train global models using Federated Learning. To this end, we propose SegViz, a federated learning-based framework to train a segmentation model from distributed non-i.i.d datasets with partial annotations. The performance of SegViz was compared against training individual models separately on each dataset as well as centrally aggregating all the datasets in one place and training a single model. The SegViz framework using FedBN as the aggregation strategy demonstrated excellent performance on the external BTCV set with dice scores of 0.93, 0.83, 0.55, and 0.75 for segmentation of liver, spleen, pancreas, and kidneys, respectively, significantly (p < 0.05) better (except spleen) than the dice scores of 0.87, 0.83, 0.42, and 0.48 for the baseline models. In contrast, the central aggregation model significantly (p < 0.05) performed poorly on the test dataset with dice scores of 0.65, 0, 0.55, and 0.68. Our results demonstrate the potential of the SegViz framework to train multi-task models from distributed datasets with partial labels. All our implementations are open-source and available at https://anonymous.4open.science/r/SegViz-B746


Localized Sparse Incomplete Multi-view Clustering

arXiv.org Artificial Intelligence

Incomplete multi-view clustering, which aims to solve the clustering problem on the incomplete multi-view data with partial view missing, has received more and more attention in recent years. Although numerous methods have been developed, most of the methods either cannot flexibly handle the incomplete multi-view data with arbitrary missing views or do not consider the negative factor of information imbalance among views. Moreover, some methods do not fully explore the local structure of all incomplete views. To tackle these problems, this paper proposes a simple but effective method, named localized sparse incomplete multi-view clustering (LSIMVC). Different from the existing methods, LSIMVC intends to learn a sparse and structured consensus latent representation from the incomplete multi-view data by optimizing a sparse regularized and novel graph embedded multi-view matrix factorization model. Specifically, in such a novel model based on the matrix factorization, a l1 norm based sparse constraint is introduced to obtain the sparse low-dimensional individual representations and the sparse consensus representation. Moreover, a novel local graph embedding term is introduced to learn the structured consensus representation. Different from the existing works, our local graph embedding term aggregates the graph embedding task and consensus representation learning task into a concise term. Furthermore, to reduce the imbalance factor of incomplete multi-view learning, an adaptive weighted learning scheme is introduced to LSIMVC. Finally, an efficient optimization strategy is given to solve the optimization problem of our proposed model. Comprehensive experimental results performed on six incomplete multi-view databases verify that the performance of our LSIMVC is superior to the state-of-the-art IMC approaches. The code is available in https://github.com/justsmart/LSIMVC.