Safe reinforcement learning (SafeRL) extends standard reinforcement learning with the idea of safety, where safety is typically defined through the constraint of the expected cost return of a trajectory being below a set limit. However, this metric fails to distinguish how costs accrue, treating infrequent severe cost events as equal to frequent mild ones, which can lead to riskier behaviors and result in unsafe exploration. We introduce a new metric, expected maximum consecutive cost steps (EMCC), which addresses safety during training by assessing the severity of unsafe steps based on their consecutive occurrence. This metric is particularly effective for distinguishing between prolonged and occasional safety violations. We apply EMMC in both on- and off-policy algorithm for benchmarking their safe exploration capability. Finally, we validate our metric through a set of benchmarks and propose a new lightweight benchmark task, which allows fast evaluation for algorithm design.

Sensitive information detection is crucial in content moderation to maintain safe online communities. Assisting in this traditionally manual process could relieve human moderators from overwhelming and tedious tasks, allowing them to focus solely on flagged content that may pose potential risks. Rapidly advancing large language models (LLMs) are known for their capability to understand and process natural language and so present a potential solution to support this process. This study explores the capabilities of five LLMs for detecting sensitive messages in the mental well-being domain within two online datasets and assesses their performance in terms of accuracy, precision, recall, F1 scores, and consistency. Our findings indicate that LLMs have the potential to be integrated into the moderation workflow as a convenient and precise detection tool. The best-performing model, GPT-4o, achieved an average accuracy of 99.5\% and an F1-score of 0.99. We discuss the advantages and potential challenges of using LLMs in the moderation workflow and suggest that future research should address the ethical considerations of utilising this technology.

Accurate segmentation of skin lesions within dermoscopic images plays a crucial role in the timely identification of skin cancer for computer-aided diagnosis on mobile platforms. However, varying shapes of the lesions, lack of defined edges, and the presence of obstructions such as hair strands and marker colors make this challenge more complex. \textcolor{red}Additionally, skin lesions often exhibit subtle variations in texture and color that are difficult to differentiate from surrounding healthy skin, necessitating models that can capture both fine-grained details and broader contextual information. Currently, melanoma segmentation models are commonly based on fully connected networks and U-Nets. However, these models often struggle with capturing the complex and varied characteristics of skin lesions, such as the presence of indistinct boundaries and diverse lesion appearances, which can lead to suboptimal segmentation performance.To address these challenges, we propose a novel lightweight network specifically designed for skin lesion segmentation utilizing mobile devices, featuring a minimal number of learnable parameters (only 0.8 million). This network comprises an encoder-decoder architecture that incorporates conformer-based focal modulation attention, self-aware local and global spatial attention, and split channel-shuffle. The efficacy of our model has been evaluated on four well-established benchmark datasets for skin lesion segmentation: ISIC 2016, ISIC 2017, ISIC 2018, and PH2. Empirical findings substantiate its state-of-the-art performance, notably reflected in a high Jaccard index.

Recent advancements in deep learning techniques have sparked performance boosts in various real-world applications including disease diagnosis based on multi-modal medical data. Cough sound data-based respiratory disease (e.g., COVID-19 and Chronic Obstructive Pulmonary Disease) diagnosis has also attracted much attention. However, existing works usually utilise traditional machine learning or deep models of moderate scales. On the other hand, the developed approaches are trained and evaluated on small-scale data due to the difficulty of curating and annotating clinical data on scale. To address these issues in prior works, we create a unified framework to evaluate various deep models from lightweight Convolutional Neural Networks (e.g., ResNet18) to modern vision transformers and compare their performance in respiratory disease classification. Based on the observations from such an extensive empirical study, we propose a novel approach to cough-based disease classification based on both self-supervised and supervised learning on a large-scale cough data set. Experimental results demonstrate our proposed approach outperforms prior arts consistently on two benchmark datasets for COVID-19 diagnosis and a proprietary dataset for COPD/non-COPD classification with an AUROC of 92.5%.

Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing accurate forecasting models remains a significant challenge. This thesis proposes two methodological frameworks using neural networks (NNs) with associated uncertainty estimates - a critical component limiting the application of NNs to epidemic forecasting thus far. We develop our frameworks by forecasting influenza-like illness (ILI) in the United States. Our first proposed method uses Web search activity data in conjunction with historical ILI rates as observations for training NN architectures. Our models incorporate Bayesian layers to produce uncertainty intervals, positioning themselves as legitimate alternatives to more conventional approaches. The best performing architecture: iterative recurrent neural network (IRNN), reduces mean absolute error by 10.3% and improves Skill by 17.1% on average in forecasting tasks across four flu seasons compared to the state-of-the-art. We build on this method by introducing IRNNs, an architecture which changes the sampling procedure in the IRNN to improve the uncertainty estimation. Our second framework uses neural ordinary differential equations to bridge the gap between mechanistic compartmental models and NNs; benefiting from the physical constraints that compartmental models provide. We evaluate eight neural ODE models utilising a mixture of ILI rates and Web search activity data to provide forecasts. These are compared with the IRNN and IRNN0 - the IRNN using only ILI rates. Models trained without Web search activity data outperform the IRNN0 by 16% in terms of Skill. Future work should focus on more effectively using neural ODEs with Web search data to compete with the best performing IRNN.

In the realm of NLP, BERT [2], extraction involves using a model to accurately identify GPT [3], and T5 [4] are some of the notable works that and classify the keyphrases in the document. The generation have consistently updated benchmark records in Pretrained of keyphrases is another task in which the model Language Model Keyphrase Extraction (PLM-predicts both present and absent keyphrases within the KPE) and Pre-trained Language Model Keyphrase Generation context of the document, introduced in [1]. The application (PLM-KPG) tasks [5], contributing significantly of deep learning technologies has witnessed to the development of NLP. a noticeable rise in using pre-trained language models The process of extracting keyphrases from a document (PLMs) in NLP in recent years. PLMs are trained using involves identifying and extracting significant different strategies on extensive text corpora and have phrases that represent the main topics or concepts discussed shown exceptional performance in various downstream within it. The primary objective is to extract the tasks, including Keyphrase Predation. PLMs using most essential and representative phrases using featurebased self-supervised learning differ from traditional learning [6, 7, 8, 9, 10] and linguistic techniques [11] methods, such as supervised learning, because they are like frequency analysis [12], part-of-speech tagging first trained on a large volume of unlabeled data before [13, 14], and syntactic parsing [15]. These methods fine-tuning small quantities of labeled data for specific can identify keyphrases based on their frequency, relevance, tasks.

Implicit Neural Representations (INRs) have recently advanced the field of deep learning due to their ability to learn continuous representations of signals without the need for large training datasets. Although INR methods have been studied for medical image super-resolution, their adaptability to localized priors in medical images has not been extensively explored. Medical images contain rich anatomical divisions that could provide valuable local prior information to enhance the accuracy and robustness of INRs. In this work, we propose a novel framework, referred to as the Semantically Conditioned INR (SeCo-INR), that conditions an INR using local priors from a medical image, enabling accurate model fitting and interpolation capabilities to achieve super-resolution. Our framework learns a continuous representation of the semantic segmentation features of a medical image and utilizes it to derive the optimal INR for each semantic region of the image. We tested our framework using several medical imaging modalities and achieved higher quantitative scores and more realistic super-resolution outputs compared to state-of-the-art methods.

Social problems stemming from the shortage of radiologists are intensifying, and artificial intelligence is being highlighted as a potential solution. Recently emerging large-scale generative AI has expanded from large language models (LLMs) to multi-modal models, showing potential to revolutionize the entire process of medical imaging. However, comprehensive reviews on their development status and future challenges are currently lacking. This scoping review systematically organizes existing literature on the clinical value of large-scale generative AI applications by following PCC guidelines. A systematic search was conducted across four databases: PubMed, EMbase, IEEE-Xplore, and Google Scholar, and 15 studies meeting the inclusion/exclusion criteria set by the researchers were reviewed. Most of these studies focused on improving the efficiency of report generation in specific parts of the interpretation process or on translating reports to aid patient understanding, with the latest studies extending to AI applications performing direct interpretations. All studies were quantitatively evaluated by clinicians, with most utilizing LLMs and only three employing multi-modal models. Both LLMs and multi-modal models showed excellent results in specific areas, but none yet outperformed radiologists in diagnostic performance. Most studies utilized GPT, with few using models specialized for the medical imaging domain. This study provides insights into the current state and limitations of large-scale generative AI-based applications in the medical imaging field, offering foundational data and suggesting that the era of medical imaging foundation models is on the horizon, which may fundamentally transform clinical practice in the near future.

Large language models (LLMs) and retrieval-augmented generation (RAG) techniques have revolutionized traditional information access, enabling AI agent to search and summarize information on behalf of users during dynamic dialogues. Despite their potential, current AI search engines exhibit considerable room for improvement in several critical areas. These areas include the support for multimodal information, the delivery of personalized responses, the capability to logically answer complex questions, and the facilitation of more flexible interactions. This paper proposes a novel AI Search Engine framework called the Agent Collaboration Network (ACN). The ACN framework consists of multiple specialized agents working collaboratively, each with distinct roles such as Account Manager, Solution Strategist, Information Manager, and Content Creator. This framework integrates mechanisms for picture content understanding, user profile tracking, and online evolution, enhancing the AI search engine's response quality, personalization, and interactivity. A highlight of the ACN is the introduction of a Reflective Forward Optimization method (RFO), which supports the online synergistic adjustment among agents. This feature endows the ACN with online learning capabilities, ensuring that the system has strong interactive flexibility and can promptly adapt to user feedback. This learning method may also serve as an optimization approach for agent-based systems, potentially influencing other domains of agent applications.

Physics-informed deep learning (PIDL)-based models have recently garnered remarkable success in traffic state estimation (TSE). However, the prior knowledge used to guide regularization training in current mainstream architectures is based on deterministic physical models. The drawback is that a solely deterministic model fails to capture the universally observed traffic flow dynamic scattering effect, thereby yielding unreliable outcomes for traffic control. This study, for the first time, proposes stochastic physics-informed deep learning (SPIDL) for traffic state estimation. The idea behind such SPIDL is simple and is based on the fact that a stochastic fundamental diagram provides the entire range of possible speeds for any given density with associated probabilities. Specifically, we select percentile-based fundamental diagram and distribution-based fundamental diagram as stochastic physics knowledge, and design corresponding physics-uninformed neural networks for effective fusion, thereby realizing two specific SPIDL models, namely \text{$\alpha$}-SPIDL and \text{$\cal B$}-SPIDL. The main contribution of SPIDL lies in addressing the "overly centralized guidance" caused by the one-to-one speed-density relationship in deterministic models during neural network training, enabling the network to digest more reliable knowledge-based constraints.Experiments on the real-world dataset indicate that proposed SPIDL models achieve accurate traffic state estimation in sparse data scenarios. More importantly, as expected, SPIDL models reproduce well the scattering effect of field observations, demonstrating the effectiveness of fusing stochastic physics model knowledge with deep learning frameworks.