Artificial Intelligence is providing astonishing results, with medicine being one of its favourite playgrounds. In a few decades, computers may be capable of formulating diagnoses and choosing the correct treatment, while robots may perform surgical operations, and conversational agents could interact with patients as virtual coaches. Machine Learning and, in particular, Deep Neural Networks are behind this revolution. In this scenario, important decisions will be controlled by standalone machines that have learned predictive models from provided data. Among the most challenging targets of interest in medicine are cancer diagnosis and therapies but, to start this revolution, software tools need to be adapted to cover the new requirements. In this sense, learning tools are becoming a commodity in Python and Matlab libraries, just to name two, but to exploit all their possibilities, it is essential to fully understand how models are interpreted and which models are more interpretable than others. In this survey, we analyse current machine learning models, frameworks, databases and other related tools as applied to medicine - specifically, to cancer research - and we discuss their interpretability, performance and the necessary input data. From the evidence available, ANN, LR and SVM have been observed to be the preferred models. Besides, CNNs, supported by the rapid development of GPUs and tensor-oriented programming libraries, are gaining in importance. However, the interpretability of results by doctors is rarely considered which is a factor that needs to be improved. We therefore consider this study to be a timely contribution to the issue.

The difficulty of classical planning increases exponentially with search-tree depth. Heuristic search can make planning more efficient, but good heuristics can be expensive to compute or may require domain-specific information, and such information may not even be available in the more general case of black-box planning. Rather than treating a given planning problem as fixed and carefully constructing a heuristic to match it, we instead rely on the simple and general-purpose "goal-count" heuristic and construct macro-actions to make it more accurate. Our approach searches for macro-actions with focused effects (i.e. macros that modify only a small number of state variables), which align well with the assumptions made by the goal-count heuristic. Our method discovers macros that dramatically improve black-box planning efficiency across a wide range of planning domains, including Rubik's cube, where it generates fewer states than the state-of-the-art LAMA planner with access to the full SAS$^+$ representation.

We introduce Performers, Transformer architectures which can estimate regular (softmax) full-rank-attention Transformers with provable accuracy, but using only linear (as opposed to quadratic) space and time complexity, without relying on any priors such as sparsity or low-rankness. To approximate softmax attention-kernels, Performers use a novel Fast Attention Via positive Orthogonal Random features approach (FAVOR+), which may be of independent interest for scalable kernel methods. FAVOR+ can be also used to efficiently model kernelizable attention mechanisms beyond softmax. This representational power is crucial to accurately compare softmax with other kernels for the first time on large-scale tasks, beyond the reach of regular Transformers, and investigate optimal attention-kernels. Performers are linear architectures fully compatible with regular Transformers and with strong theoretical guarantees: unbiased or nearly-unbiased estimation of the attention matrix, uniform convergence and low estimation variance. We tested Performers on a rich set of tasks stretching from pixel-prediction through text models to protein sequence modeling. We demonstrate competitive results with other examined efficient sparse and dense attention methods, showcasing effectiveness of the novel attention-learning paradigm leveraged by Performers.

General fuzzy min-max neural network (GFMMNN) is one of the efficient neuro-fuzzy systems for data classification. However, one of the downsides of its original learning algorithms is the inability to handle and learn from the mixed-attribute data. While categorical features encoding methods can be used with the GFMMNN learning algorithms, they exhibit a lot of shortcomings. Other approaches proposed in the literature are not suitable for on-line learning as they require entire training data available in the learning phase. With the rapid change in the volume and velocity of streaming data in many application areas, it is increasingly required that the constructed models can learn and adapt to the continuous data changes in real-time without the need for their full retraining or access to the historical data. This paper proposes an extended online learning algorithm for the GFMMNN. The proposed method can handle the datasets with both continuous and categorical features. The extensive experiments confirmed superior and stable classification performance of the proposed approach in comparison to other relevant learning algorithms for the GFMM model.

Autism Spectrum Disorder (ASD), which is a neuro development disorder, is often accompanied by sensory issues such an over sensitivity or under sensitivity to sounds and smells or touch. Although its main cause is genetics in nature, early detection and treatment can help to improve the conditions. In recent years, machine learning based intelligent diagnosis has been evolved to complement the traditional clinical methods which can be time consuming and expensive. The focus of this paper is to find out the most significant traits and automate the diagnosis process using available classification techniques for improved diagnosis purpose. We have analyzed ASD datasets of Toddler, Child, Adolescent and Adult. We determine the best performing classifier for these binary datasets using the evaluation metrics recall, precision, F-measures and classification errors. Our finding shows that Sequential minimal optimization (SMO) based Support Vector Machines (SVM) classifier outperforms all other benchmark machine learning algorithms in terms of accuracy during the detection of ASD cases and produces less classification errors compared to other algorithms. Also, we find that Relief Attributes algorithm is the best to identify the most significant attributes in ASD datasets.

Transformer models have achieved state-of-the-art results across a diverse range of domains. However, concern over the cost of training the attention mechanism to learn complex dependencies between distant inputs continues to grow. In response, solutions that exploit the structure and sparsity of the learned attention matrix have blossomed. However, real-world applications that involve long sequences, such as biological sequence analysis, may fall short of meeting these assumptions, precluding exploration of these models. To address this challenge, we present a new Transformer architecture, Performer, based on Fast Attention Via Orthogonal Random features (FAVOR). Our mechanism scales linearly rather than quadratically in the number of tokens in the sequence, is characterized by sub-quadratic space complexity and does not incorporate any sparsity pattern priors. Furthermore, it provides strong theoretical guarantees: unbiased estimation of the attention matrix and uniform convergence. It is also backwards-compatible with pre-trained regular Transformers. We demonstrate its effectiveness on the challenging task of protein sequence modeling and provide detailed theoretical analysis.

Submitted to INFORMS Journal on Applied Analytics manuscript (Please, provide the manuscript number!) Authors are encouraged to submit new papers to INFORMS journals by means of a style file template, which includes the journal title. However, use of a template does not certify that the paper has been accepted for publication in the named journal. INFORMS journal templates are for the exclusive purpose of submitting to an INFORMS journal and should not be used to distribute the papers in print or online or to submit the papers to another publication. In this paper, we introduce an optimization problem posed by the Music Building Eindhoven (MBE) to deal with the economical consequences of the COVID-19 pandemic for theatre halls. We propose a model for maximizing the number of guests in a theatre hall that respects social distancing rules, and is based on trapezoid packings. Computational results show that up to 40% of the normal capacity can be used for a single show setting, and up to 70 % in case artists opt for two consecutive performances per evening. All around the world, the corona-crisis has hit the cultural sector hard. Festivals are cancelled, orchestra's are at the brink of bankruptcy, choirs have stopped performing, and theatres are struggling to survive.

Pretrained language models, especially masked language models (MLMs) have seen success across many NLP tasks. However, there is ample evidence that they use the cultural biases that are undoubtedly present in the corpora they are trained on, implicitly creating harm with biased representations. To measure some forms of social bias in language models against protected demographic groups in the US, we introduce the Crowdsourced Stereotype Pairs benchmark (CrowS-Pairs). CrowS-Pairs has 1508 examples that cover stereotypes dealing with nine types of bias, like race, religion, and age. In CrowS-Pairs a model is presented with two sentences: one that is more stereotyping and another that is less stereotyping. The data focuses on stereotypes about historically disadvantaged groups and contrasts them with advantaged groups. We find that all three of the widely-used MLMs we evaluate substantially favor sentences that express stereotypes in every category in CrowS-Pairs. As work on building less biased models advances, this dataset can be used as a benchmark to evaluate progress.

While neural sequence learning methods have made significant progress in single-document summarization (SDS), they produce unsatisfactory results on multi-document summarization (MDS). We observe two major challenges when adapting SDS advances to MDS: (1) MDS involves larger search space and yet more limited training data, setting obstacles for neural methods to learn adequate representations; (2) MDS needs to resolve higher information redundancy among the source documents, which SDS methods are less effective to handle. To close the gap, we present RL-MMR, Maximal Margin Relevance-guided Reinforcement Learning for MDS, which unifies advanced neural SDS methods and statistical measures used in classical MDS. RL-MMR casts MMR guidance on fewer promising candidates, which restrains the search space and thus leads to better representation learning. Additionally, the explicit redundancy measure in MMR helps the neural representation of the summary to better capture redundancy. Extensive experiments demonstrate that RL-MMR achieves state-of-the-art performance on benchmark MDS datasets. In particular, we show the benefits of incorporating MMR into end-to-end learning when adapting SDS to MDS in terms of both learning effectiveness and efficiency.

The most comprehensive deep-sea study of two marine parks off Australia has given a fascinating glimpse into what lives there. Scientists have told the BBC how they used an underwater robot to make a host of discoveries.