We perform unsupervised analysis of image-derived shape and motion features extracted from 3822 cardiac 4D MRIs of the UK Biobank. First, with a feature extraction method previously published based on deep learning models, we extract from each case 9 feature values characterizing both the cardiac shape and motion. Second, a feature selection is performed to remove highly correlated feature pairs. Third, clustering is carried out using a Gaussian mixture model on the selected features. After analysis, we identify two small clusters which probably correspond to two pathological categories. Further confirmation using a trained classification model and dimensionality reduction tools is carried out to support this discovery. Moreover, we examine the differences between the other large clusters and compare our measures with the ground-truth.

BACKGROUND AND PURPOSE: Alberta Stroke Program Early CT Score (ASPECTS) was devised as a systematic method to assess the extent of early ischemic change on noncontrast CT (NCCT) in patients with acute ischemic stroke (AIS). Our aim was to automate ASPECTS to objectively score NCCT of AIS patients. MATERIALS AND METHODS: We collected NCCT images with a 5-mm thickness of 257 patients with acute ischemic stroke ( 8 hours from onset to scans) followed by a diffusion-weighted imaging acquisition within 1 hour. Expert ASPECTS readings on DWI were used as ground truth. Texture features were extracted from each ASPECTS region of the 157 training patient images to train a random forest classifier. The unseen 100 testing patient images were used to evaluate the performance of the trained classifier.

A new Canadian study has linked increased screen time with delayed development in children, adding new fuel to the debate over how long is too long for kids to spend in front of their electronic devices. Researchers from the University of Waterloo, University of Calgary and Alberta Children's Hospital Research Institute said toddlers who spent more time watching a screen at 2 years old did worse on developmental markers than those who spent less time watching a screen. "What is new in this study is that we are studying really young children, so aged 2-5, when brain development is really rapidly progressing and also child development is unfolding so rapidly," Dr. Sheri Madigan told the Guardian. "We are getting at these lasting effects." The authors of the study, who tested 2,400 children, say parents should be cautious about how long they allow their kids to spend on their devices.

Supervised training of neural networks for classification is typically performed with a global loss function. The loss function provides a gradient for the output layer, and this gradient is back-propagated to hidden layers to dictate an update direction for the weights. An alternative approach is to train the network with layer-wise loss functions. In this paper we demonstrate, for the first time, that layer-wise training can approach the state-of-the-art on a variety of image datasets. We use single-layer sub-networks and two different supervised loss functions to generate local error signals for the hidden layers, and we show that the combination of these losses help with optimization in the context of local learning. Using local errors could be a step towards more biologically plausible deep learning because the global error does not have to be transported back to hidden layers. A completely backprop free variant outperforms previously reported results among methods aiming for higher biological plausibility. Code is available https://github.com/anokland/local-loss

While there are only a few companies using artificial intelligence in production, it's certainly where the future lies. In this wide-ranging episode of The New Stack Makers podcast, we talk with Ted Dunning, chief application architect at MapR and author, along with Ellen Friedman, of the new O'Reilly book "AI and Analytics in Production." We all have an image in the back of our minds of computers taking over the world, but the truth for the short-term, said Dunning, is that some of the best value for artificial intelligence (AI) is going to be some of the most boring stuff. AI, at least in the beginning, will replace boring repetitive tasks and mine massive amounts of data in ways not previously imaginable. As you accumulate data, said Dunning, it begins to have interesting synergistic effects, so that the raw value can go up in unexpected ways.

The exploitation of large-scale population data has the potential to improve healthcare by discovering and understanding patterns and trends within this data. To enable high throughput analysis of cardiac imaging data automatically, a pipeline should comprise quality monitoring of the input images, segmentation of the cardiac structures, assessment of the segmentation quality, and parsing of cardiac functional indexes. We present a fully automatic, high throughput image parsing workflow for the analysis of cardiac MR images, and test its performance on the UK Biobank (UKB) cardiac dataset. The proposed pipeline is capable of performing end-to-end image processing including: data organisation, image quality assessment, shape model initialisation, segmentation, segmentation quality assessment, and functional parameter computation; all without any user interaction. To the best of our knowledge,this is the first paper tackling the fully automatic 3D analysis of the UKB population study, providing reference ranges for all key cardiovascular functional indexes, from both left and right ventricles of the heart. We tested our workflow on a reference cohort of 800 healthy subjects for which manual delineations, and reference functional indexes exist. Our results show statistically significant agreement between the manually obtained reference indexes, and those automatically computed using our framework.

This paper proposes Dirichlet Variational Autoencoder (DirVAE) using a Dirichlet prior for a continuous latent variable that exhibits the characteristic of the categorical probabilities. To infer the parameters of DirVAE, we utilize the stochastic gradient method by approximating the Gamma distribution, which is a component of the Dirichlet distribution, with the inverse Gamma CDF approximation. Additionally, we reshape the component collapsing issue by investigating two problem sources, which are decoder weight collapsing and latent value collapsing, and we show that DirVAE has no component collapsing; while Gaussian VAE exhibits the decoder weight collapsing and Stick-Breaking VAE shows the latent value collapsing. The experimental results show that 1) DirVAE models the latent representation result with the best log-likelihood compared to the baselines; and 2) DirVAE produces more interpretable latent values with no collapsing issues which the baseline models suffer from. Also, we show that the learned latent representation from the DirVAE achieves the best classification accuracy in the semi-supervised and the supervised classification tasks on MNIST, OMNIGLOT, and SVHN compared to the baseline VAEs. Finally, we demonstrated that the DirVAE augmented topic models show better performances in most cases.

Acoustic scene classification is the task of identifying the scene from which the audio signal is recorded. Convolutional neural network (CNN) models are widely adopted with proven successes in acoustic scene classification. However, there is little insight on how an audio scene is perceived in CNN, as what have been demonstrated in image recognition research. In the present study, the Class Activation Mapping (CAM) is utilized to analyze how the log-magnitude Mel-scale filter-bank (log-Mel) features of different acoustic scenes are learned in a CNN classifier. It is noted that distinct high-energy time-frequency components of audio signals generally do not correspond to strong activation on CAM, while the background sound texture are well learned in CNN. In order to make the sound texture more salient, we propose to apply the Difference of Gaussian (DoG) and Sobel operator to process the log-Mel features and enhance edge information of the time-frequency image. Experimental results on the DCASE 2017 ASC challenge show that using edge enhanced log-Mel images as input feature of CNN significantly improves the performance of audio scene classification.

Abstract--In power systems, an asset class is a group of power equipment that has the same function and shares similar electrical or mechanical characteristics. Predicting failures for different asset classes is critical for electric utilities towards developing cost-effective asset management strategies. Previously, physical age based Weibull distribution has been widely used to failure prediction. However, this mathematical model cannot incorporate asset condition data such as inspection or testing results. As a result, the prediction cannot be very specific and accurate for individual assets. To solve this important problem, this paper proposes a novel and comprehensive data-driven approach based on asset condition data: K-means clustering as an unsupervised learning method is used to analyze the inner structure of historical asset condition data and produce the asset conditional ages; logistic regression as a supervised learning method takes in both asset physical ages and conditional ages to classify and predict asset statuses. Furthermore, an index called average aging rate is defined to quantify, track and estimate the relationship between asset physical age and conditional age. This approach was applied to an urban distribution system in West Canada to predict medium-voltage cable failures. Case studies and comparison with standard Weibull distribution are provided. The proposed approach demonstrates superior performance and practicality for predicting asset class failures in power systems. I. INTRODUCTION oday, more and more electric utilities are mandated by regulators to develop cost-effective long-term asset management strategies to reduce overall cost while maintaining system reliability [1-2]. Sophisticated and optimal asset management strategies can only be established based on the accurate prediction of asset failures in the future.

Multiplicative noise, including dropout, is widely used to regularize deep neural networks (DNNs), and is shown to be effective in a wide range of architectures and tasks. From an information perspective, we consider injecting multiplicative noise into a DNN as training the network to solve the task with noisy information pathways, which leads to the observation that multiplicative noise tends to increase the correlation between features, so as to increase the signal-to-noise ratio of information pathways. However, high feature correlation is undesirable, as it increases redundancy in representations. In this work, we propose non-correlating multiplicative noise (NCMN), which exploits batch normalization to remove the correlation effect in a simple yet effective way. We show that NCMN significantly improves the performance of standard multiplicative noise on image classification tasks, providing a better alternative to dropout for batch-normalized networks. Additionally, we present a unified view of NCMN and shake-shake regularization, which explains the performance gain of the latter.