Europe
AIDebate Aids Assessment of Controversial Claims
As AI grows more powerful, it will increasingly shape how we understand the world. But with this influence comes the risk of amplifying misinformation and deepening social divides--especially on consequential topics where factual accuracy directly impacts well-being. Scalable Oversight aims to ensure AI systems remain truthful even when their capabilities exceed those of their evaluators. Yet when humans serve as evaluators, their own beliefs and biases can impair judgment. We study whether AI debate can guide biased judges toward the truth by having two AI systems debate opposing sides of controversial factuality claims on COVID-19 and climate change where people hold strong prior beliefs.
Joint Design of Protein Surface and Structure Using a Diffusion Bridge Model
Protein-protein interactions (PPIs) are governed by surface complementarity and hydrophobic interactions at protein interfaces. However, designing diverse and physically realistic protein structure and surfaces that precisely complement target receptors remains a significant challenge in computational protein design. In this work, we introduce PepBridge, a novel framework for the joint design of protein surface and structure that seamlessly integrates receptor surface geometry and biochemical properties. Starting with a receptor surface represented as a 3D point cloud, PepBridge generates complete protein structures through a multi-step process. First, it employs denoising diffusion bridge models (DDBMs) to map receptor surfaces to ligand surfaces. Next, a multi-model diffusion model predicts the corresponding structure, while Shape-Frame Matching Networks ensure alignment between surface geometry and backbone architecture. This integrated approach facilitates surface complementarity, conformational stability, and chemical feasibility. Extensive validation across diverse protein design scenarios demonstrates PepBridge's efficacy in generating structurally viable proteins, representing a significant advancement in the joint design of top-down protein structure.
Online robust locally differentially private learning for nonparametric regression
The growing prevalence of streaming data and increasing concerns over data privacy pose significant challenges for traditional nonparametric regression methods, which are often ill-suited for real-time, privacy-aware learning. In this paper, we tackle these issues by first proposing a novel one-pass online functional stochastic gradient descent algorithm that leverages the Huber loss (H-FSGD), to improve robustness against outliers and heavy-tailed errors in dynamic environments. To further accommodate privacy constraints, we introduce a locally differentially private extension, Private H-FSGD (PH-FSGD), designed to real-time, privacy-preserving estimation. Theoretically, we conduct a comprehensive non-asymptotic convergence analysis of the proposed estimators, establishing finite-sample guarantees and identifying optimal step size schedules that achieve optimal convergence rates. In particular, we provide practical insights into the impact of key hyperparameters, such as step size and privacy budget, on convergence behavior. Extensive experiments validate our theoretical findings, demonstrating that our methods achieve strong robustness and privacy protection without sacrificing efficiency.
PhysioWave: AMulti-Scale Wavelet-Transformer for Physiological Signal Representation
Physiological signals are often corrupted by motion artifacts, baseline drift, and other low-SNR disturbances, which pose significant challenges for analysis. Additionally, these signals exhibit strong non-stationarity, with sharp peaks and abrupt changes that evolve continuously, making them difficult to represent using traditional time-domain or filtering methods. To address these issues, a novel waveletbased approach for physiological signal analysis is presented, aiming to capture multi-scale time-frequency features in various physiological signals. Leveraging this technique, two large-scale pretrained models specific to EMG and ECG are introduced for the first time, achieving superior performance and setting new baselines in downstream tasks. Additionally, a unified multi-modal framework is constructed by integrating pretrained EEG model, where each modality is guided through its dedicated branch and fused via learnable weighted fusion. This design effectively addresses challenges such as low signal-to-noise ratio, high inter-subject variability, and device mismatch, outperforming existing methods on multi-modal tasks. The proposed wavelet-based architecture lays a solid foundation for analysis of diverse physiological signals, while the multi-modal design points to nextgeneration physiological signal processing with potential impact on wearable health monitoring, clinical diagnostics, and broader biomedical applications.
Generalizable Insights for Graph Transformers in Theory and Practice
Graph transformers (GTs) have shown strong empirical performance, yet current architectures vary widely in their use of attention mechanisms, positional embeddings (PEs), and expressivity. Existing expressivity results are often tied to specific design choices and lack comprehensive empirical validation on large-scale data. This leaves a gap between theory and practice, preventing generalizable insights that exceed particular application domains. Here, we propose the GeneralizedDistance Transformer (GDT), a GT architecture based on standard attention that incorporates many recent advancements for GTs, and we develop a fine-grained understanding of the GDT's representation power in terms of attention and PEs. Through extensive experiments, we identify design choices that consistently perform well across various applications, tasks, and model scales, demonstrating strong performance in a few-shot transfer setting without fine-tuning. Our evaluation covers over eight million graphs with roughly 270M tokens across diverse domains, including image-based object detection, molecular property prediction, code summarization, and out-of-distribution algorithmic reasoning.
LrcSSM block repeat #blocks times
We present LrcSSM, a non-linear recurrent model that processes long sequences as fast as today's linear state-space layers. By forcing its Jacobian matrix to be diagonal, the full sequence can be solved in parallel, giving O(TD) computational work and memory and only O(logT) sequential depth, for input-sequence length T and a state dimension D. Moreover, LrcSSM offers a formal gradient-stability guarantee that other input-varying systems such as Liquid-S4 and Mamba do not provide. Importantly, the diagonal Jacobian structure of our model results in no performance loss compared to the original model with dense Jacobian, and the approach can be generalized to other non-linear recurrent models, demonstrating broader applicability. On a suite of long-range forecasting tasks, we demonstrate that LrcSSM outperforms Transformers, LRU, S5, and Mamba.
Proper Hรถlder-Kullback Dirichlet Diffusion: A Framework for High Dimensional Generative Modeling
Diffusion-based generative models have long depended on Gaussian priors, with little exploration of alternative distributions. We introduce a Proper Hรถlder-Kullback Dirichlet framework that uses time-varying multiplicative transformations to define both forward and reverse diffusion processes. Moving beyond conventional reweighted evidence lower bounds (ELBO) or Kullback-Leibler upper bounds (KLUB), we propose two novel divergence measures: the Proper Hรถlder Divergence (PHD) and the Proper Hรถlder-Kullback (PHK) divergence, the latter designed to restore symmetry missing in existing formulations. When optimizing our Dirichlet diffusion model with PHK, we achieve a Frรฉchet Inception Distance (FID) of 2.78 on unconditional CIFAR-10. Comprehensive experiments on natural-image datasets validate the generative strengths of model and confirm PHK's effectiveness in model training. These contributions expand the diffusion-model family with principled non-Gaussian processes and effective optimization tools, offering new avenues for versatile, high-fidelity generative modeling.
DynamicRAG: Leveraging Outputs of Large Language Model as Feedback for Dynamic Reranking in Retrieval-Augmented Generation
Retrieval-augmented generation (RAG) systems combine large language models (LLMs) with external knowledge retrieval, making them highly effective for knowledge-intensive tasks. A crucial but often under-explored component of these systems is the reranker. Since irrelevant documents in RAG systems can mislead the generator, the reranker plays a vital role in refining retrieved documents to enhance generation quality and explainability. However, it is challenging to determine the appropriate number of documents (k) that the reranker should select: too few may result in missing critical information, while too many introduce noise and inefficiencies. Although recent studies have explored LLM-based rerankers, they primarily leverage internal model knowledge and overlook the rich supervisory signals that LLMs can provide, such as using response quality as feedback for optimizing reranking decisions. In this paper, we propose DynamicRAG, a novel RAG framework where the reranker dynamically adjusts both the order and number of retrieved documents based on the query. We model the reranker as an agent optimized through reinforcement learning (RL), using rewards derived from LLM output quality. Across seven knowledge-intensive datasets, DynamicRAG demonstrates superior performance, achieving state-of-the-art results among models of same parameter sizes.
Mitigating Privacy-Utility Trade-off in Decentralized Federated Learning via f-Differential Privacy
Differentially private (DP) decentralized Federated Learning (FL) allows local users to collaborate without sharing their data with a central server. However, accurately quantifying the privacy budget of private FL algorithms is challenging due to the co-existence of complex algorithmic components such as decentralized communication and local updates.