In these types of synapses, the short-term dynamics of the synaptic efficacies are governed by the relative timing of the pre-and post-synaptic spikes, while on long time scales the efficacies tend asymptotically to either a potentiated state or to a depressed one. We fabricated a prototype VLSI chip containing a network of integrate and fire neurons interconnected via bistable STDP synapses. Test results from this chip demonstrate the synapse's STDP learning properties, and its long-term bistable characteristics.

We introduce a class of string kernels, called mismatch kernels, for use with support vector machines (SVMs) in a discriminative approach to the protein classification problem.

In Slow Feature Analysis (SFA [1]), it has been demonstrated that high-order invariant properties can be extracted by projecting inputs intoa nonlinear space and computing the slowest changing features in this space; this has been proposed as a simple general model for learning nonlinear invariances in the visual system. However, thismethod is highly constrained by the curse of dimensionality which limits it to simple theoretical simulations. This paper demonstrates that by using a different but closely-related objective function for extracting slowly varying features ([2, 3]), and then exploiting thekernel trick, this curse can be avoided. Using this new method we show that both the complex cell properties of translation invarianceand disparity coding can be learnt simultaneously from natural images when complex cells are driven by simple cells also learnt from the image. The notion of maximising an objective function based upon the temporal predictability ofoutput has been progressively applied in modelling the development of invariances in the visual system.

Bayesian decoding to account for the presentation of multiple objects.

A key challenge for neural modeling is to explain how a continuous stream of multi-modal input from a rapidly changing environment can be processed by stereotypical recurrent circuits of integrate-and-fire neurons in real-time. We propose a new computational model that is based on principles of high dimensional dynamical systems in combination with statistical learning theory. It can be implemented on generic evolved or found recurrent circuitry.

The Bayesian paradigm provides a natural and effective means of exploiting priorknowledge concerning the time-frequency structure of sound signals such as speech and music--something which has often been overlooked intraditional audio signal processing approaches. Here, after constructing aBayesian model and prior distributions capable of taking into account the time-frequency characteristics of typical audio waveforms, we apply Markov chain Monte Carlo methods in order to sample from the resultant posterior distribution of interest. We present speech enhancement resultswhich compare favourably in objective terms with standard time-varying filtering techniques (and in several cases yield superior performance, bothobjectively and subjectively); moreover, in contrast to such methods, our results are obtained without an assumption of prior knowledge of the noise power.

A standard view of memory consolidation is that episodes are stored temporarily inthe hippocampus, and are transferred to the neocortex through replay. Various recent experimental challenges to the idea of transfer, particularly for human memory, are forcing its reevaluation. However, although there is independent neurophysiological evidence for replay, short of transfer, there are few theoretical ideas for what it might be doing. We suggest and demonstrate two important computational roles associated with neocortical indices.

We report a system that classifies and can learn to classify patterns of visual motion online. The complete system is described by the dynamics ofits physical network architectures. The combination of the following propertiesmakes the system novel: Firstly, the front-end of the system consists of an aVLSI optical flow chip that collectively computes 2-D global visual motion in real-time [1]. Secondly, the complexity of the classification task is significantly reduced by mapping the continuous motiontrajectories to sequences of'motion events'. And thirdly, all the network structures are simple and with the exception of the optical flow chip based on a Winner-Take-All (WTA) architecture. We demonstrate theapplication of the proposed generic system for a contactless man-machine interface that allows to write letters by visual motion. Regarding thelow complexity of the system, its robustness and the already existing front-end, a complete aVLSI system-on-chip implementation is realistic, allowing various applications in mobile electronic devices.

The problem of learning a semantic representation of a text document from data is addressed, in the situation where a corpus of unlabeled paired documents is available, each pair being formed by a short English documentand its French translation. This representation can then be used for any retrieval, categorization or clustering task, both in a standard andin a cross-lingual setting. By using kernel functions, in this case simple bag-of-words inner products, each part of the corpus is mapped to a high-dimensional space. The correlations between the two spaces are then learnt by using kernel Canonical Correlation Analysis. A set of directions is found in the first and in the second space that are maximally correlated.Since we assume the two representations are completely independentapart from the semantic content, any correlation between them should reflect some semantic similarity. Certain patterns of English words that relate to a specific meaning should correlate with certain patternsof French words corresponding to the same meaning, across the corpus. Using the semantic representation obtained in this way we first demonstrate that the correlations detected between the two versions of the corpus are significantly higher than random, and hence that a representation basedon such features does capture statistical patterns that should reflect semantic information. Then we use such representation both in cross-language and in single-language retrieval tasks, observing performance that is consistently and significantly superior to LSI on the same data.

We introduce the notion of Morton-style factorial coding and illustrate how it may help understand information integration and perceptual coding inthe brain. We show that by focusing on average responses one may miss the existence of factorial coding mechanisms that become only apparent when analyzing spike count histograms. We show evidence suggesting that the classical/nonclassical receptive field organization in the cortex effectively enforces the development of Morton-style factorial codes. This may provide some cues to help understand perceptual coding inthe brain and to develop new unsupervised learning algorithms. While methods like ICA (Bell & Sejnowski, 1997) develop independent codes, in Morton-style coding the goal is to make two or more external aspects of the world become independent when conditioning on internal representations.