This paper presents a novel method for the reconstruction of a neural network connectivity using calcium fluorescence data. We introduce a fast unsupervised method to integrate different networks that reconstructs structural connectivity from neuron activity. Our method improves the state-of-the-art reconstruction method General Transfer Entropy (GTE). We are able to better eliminate indirect links, improving therefore the quality of the network via a normalization and ensemble process of GTE and three new informative features. The approach is based on a simple combination of networks, which is remarkably fast. The performance of our approach is benchmarked on simulated time series provided at the connectomics challenge and also submitted at the public competition.

Cortana is taking the war of words to Siri's home turf, Amazon amazes us with its tax return, and we find out why the record industry has a love-hate relationship with YouTube. Microsoft is challenging Apple's voice-activated personal assistant Siri by bringing its own voice control system Cortana to iPhones, not to mention Android devices too. It's all part of the build-up to Windows 10, but will iPhone owners switch allegiance? Amazon is changing the way it operates in Europe to pay more taxes in individual countries, ending its much-criticised wheeze of exploiting the tax haven of Luxembourg. Tax doesn't have to be taxing.

MOL Group announced yesterday the winners of the Freshhh 2015 competition, which sees students from all over the world compete in technology and business strategy simulations related to the oil and gas industry. 'Just Ask Siri', consisting of three students from the Prague University of Economics and the Czech Technical University, was awarded first place, with Hungary's'Oil's Creed' and Slovenia's'Decore' teams placing in second and third respectively. All three teams will now be given the opportunity to join MOL Group's graduate recruitment and development program. MOL Group HR Vice President Zdravka Demeter Bubalo commented in a company statement: "We congratulate the top three teams for winning the Freshhh competition 2015. I would like to thank all participants for their endless efforts during the competition. It is incredible to see how young students work with such difficult real-life cases and always find new solutions. The outstanding results from the participants and number of applications are showing us once more that we are heading in the right direction in order to attract top talents of the oil and gas industry."

Stochastic variational inference allows for fast posterior inference in complex Bayesian models. However, the algorithm is prone to local optima which can make the quality of the posterior approximation sensitive to the choice of hyperparameters and initialization. We address this problem by replacing the natural gradient step of stochastic varitional inference with a trust-region update. We show that this leads to generally better results and reduced sensitivity to hyperparameters. We also describe a new strategy for variational inference on streaming data and show that here our trust-region method is crucial for getting good performance.

Event models obtained automatically from video can be used in applications ranging from abnormal event detection to content based video retrieval. When multiple agents are involved in the events, characterizing events naturally suggests encoding interactions as relations. Learning event models from this kind of relational spatio-temporal data using relational learning techniques such as Inductive Logic Programming (ILP) hold promise, but have not been successfully applied to very large datasets which result from video data. In this paper, we present a novel framework REMIND (Relational Event Model INDuction) for supervised relational learning of event models from large video datasets using ILP. Efficiency is achieved through the learning from interpretations setting and using a typing system that exploits the type hierarchy of objects in a domain. The use of types also helps prevent over generalization. Furthermore, we also present a type-refining operator and prove that it is optimal. The learned models can be used for recognizing events from previously unseen videos. We also present an extension to the framework by integrating an abduction step that improves the learning performance when there is noise in the input data. The experimental results on several hours of video data from two challenging real world domains (an airport domain and a physical action verbs domain) suggest that the techniques are suitable to real world scenarios.

The article introduces a ceteris paribus modal logic, called CP, interpreted on the equivalence classes induced by finite sets of propositional atoms. This logic is studied and then used to embed three logics of strategic interaction, namely atemporal STIT, the coalition logic of propositional control (CL PC) and the starless fragment of the dynamic logic of propositional assignments (DL PA). The embeddings highlight a common ceteris paribus structure underpinning the key operators of all these apparently very different logics and show, we argue, remarkable similarities behind some of the most influential formalisms for reasoning about strategic interaction.

We propose Coactive Learning as a model of interaction between a learning system and a human user, where both have the common goal of providing results of maximum utility to the user. Interactions in the Coactive Learning model take the following form: at each step, the system (e.g. search engine) receives a context (e.g. query) and predicts an object (e.g. ranking); the user responds by correcting the system if necessary, providing a slightly improved but not necessarily optimal object as feedback. We argue that such preference feedback can be inferred in large quantity from observable user behavior (e.g., clicks in web search), unlike the optimal feedback required in the expert model or the cardinal valuations required for bandit learning. Despite the relaxed requirements for the feedback, we show that it is possible to adapt many existing online learning algorithms to the coactive framework. In particular, we provide algorithms that achieve square root regret in terms of cardinal utility, even though the learning algorithm never observes cardinal utility values directly. We also provide an algorithm with logarithmic regret in the case of strongly convex loss functions. An extensive empirical study demonstrates the applicability of our model and algorithms on a movie recommendation task, as well as ranking for web search.

Metagenomics characterizes the taxonomic diversity of microbial communities by sequencing DNA directly from an environmental sample. One of the main challenges in metagenomics data analysis is the binning step, where each sequenced read is assigned to a taxonomic clade. Due to the large volume of metagenomics datasets, binning methods need fast and accurate algorithms that can operate with reasonable computing requirements. While standard alignment-based methods provide state-of-the-art performance, compositional approaches that assign a taxonomic class to a DNA read based on the k-mers it contains have the potential to provide faster solutions. In this work, we investigate the potential of modern, large-scale machine learning implementations for taxonomic affectation of next-generation sequencing reads based on their k-mers profile. We show that machine learning-based compositional approaches benefit from increasing the number of fragments sampled from reference genome to tune their parameters, up to a coverage of about 10, and from increasing the k-mer size to about 12. Tuning these models involves training a machine learning model on about 10 8 samples in 10 7 dimensions, which is out of reach of standard soft-wares but can be done efficiently with modern implementations for large-scale machine learning. The resulting models are competitive in terms of accuracy with well-established alignment tools for problems involving a small to moderate number of candidate species, and for reasonable amounts of sequencing errors. We show, however, that compositional approaches are still limited in their ability to deal with problems involving a greater number of species, and more sensitive to sequencing errors. We finally confirm that compositional approach achieve faster prediction times, with a gain of 3 to 15 times with respect to the BWA-MEM short read mapper, depending on the number of candidate species and the level of sequencing noise.

We explore the connection between two problems that have arisen independently in the signal processing and related fields: the estimation of the geometric mean of a set of symmetric positive definite (SPD) matrices and their approximate joint diagonalization (AJD). Today there is a considerable interest in estimating the geometric mean of a SPD matrix set in the manifold of SPD matrices endowed with the Fisher information metric. The resulting mean has several important invariance properties and has proven very useful in diverse engineering applications such as biomedical and image data processing. While for two SPD matrices the mean has an algebraic closed form solution, for a set of more than two SPD matrices it can only be estimated by iterative algorithms. However, none of the existing iterative algorithms feature at the same time fast convergence, low computational complexity per iteration and guarantee of convergence. For this reason, recently other definitions of geometric mean based on symmetric divergence measures, such as the Bhattacharyya divergence, have been considered. The resulting means, although possibly useful in practice, do not satisfy all desirable invariance properties. In this paper we consider geometric means of co-variance matrices estimated on high-dimensional time-series, assuming that the data is generated according to an instantaneous mixing model, which is very common in signal processing. We show that in these circumstances we can approximate the Fisher information geometric mean by employing an efficient AJD algorithm. Our approximation is in general much closer to the Fisher information geometric mean as compared to its competitors and verifies many invariance properties. Furthermore, convergence is guaranteed, the computational complexity is low and the convergence rate is quadratic. The accuracy of this new geometric mean approximation is demonstrated by means of simulations.

An important form of prior information in clustering comes in form of cannot-link and must-link constraints. We present a generalization of the popular spectral clustering technique which integrates such constraints. Motivated by the recently proposed $1$-spectral clustering for the unconstrained problem, our method is based on a tight relaxation of the constrained normalized cut into a continuous optimization problem. Opposite to all other methods which have been suggested for constrained spectral clustering, we can always guarantee to satisfy all constraints. Moreover, our soft formulation allows to optimize a trade-off between normalized cut and the number of violated constraints. An efficient implementation is provided which scales to large datasets. We outperform consistently all other proposed methods in the experiments.