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Graph-Driven Feature Extraction From Microarray Data Using Diffusion Kernels and Kernel CCA

Neural Information Processing Systems

We present an algorithm to extract features from high-dimensional gene expression profiles, based on the knowledge of a graph which links together genes known to participate to successive reactions in metabolic pathways. Motivated by the intuition that biologically relevant features are likely to exhibit smoothness with respect to the graph topology, the algorithm involves encoding the graph and the set of expression profiles into kernel functions, and performing a generalized form of canonical correlation analysis in the corresponding reproducible kernel Hilbert spaces. Function prediction experiments for the genes of the yeast S. Cerevisiae validate this approach by showing a consistent increase in performance when a state-of-the-art classifier uses the vector of features instead of the original expression profile to predict the functional class of a gene.


Ranking with Large Margin Principle: Two Approaches

Neural Information Processing Systems

We discuss the problem of ranking k instances with the use of a "large margin" principle. We introduce two main approaches: the first is the "fixed margin" policy in which the margin of the closest neighboring classes is being maximized - which turns out to be a direct generalization of SVM to ranking learning. The second approach allows for k - 1 different margins where the sum of margins is maximized. This approach is shown to reduce to lI-SVM when the number of classes k 2. Both approaches are optimal in size of 21 where I is the total number of training examples. Experiments performed on visual classification and "collaborative filtering" show that both approaches outperform existing ordinal regression algorithms applied for ranking and multi-class SVM applied to general multi-class classification.


FloatBoost Learning for Classification

Neural Information Processing Systems

AdaBoost [3] minimizes an upper error bound which is an exponential function of the margin on the training set [14]. However, the ultimate goal in applications of pattern classification is always minimum error rate. On the other hand, AdaBoost needs an effective procedure for learning weak classifiers, which by itself is difficult especially for high dimensional data. In this paper, we present a novel procedure, called FloatBoost, for learning a better boosted classifier. FloatBoost uses a backtrack mechanism after each iteration of AdaBoost to remove weak classifiers which cause higher error rates. The resulting float-boosted classifier consists of fewer weak classifiers yet achieves lower error rates than AdaBoost in both training and test. We also propose a statistical model for learning weak classifiers, based on a stagewise approximation of the posterior using an overcomplete set of scalar features. Experimental comparisons of FloatBoost and AdaBoost are provided through a difficult classification problem, face detection, where the goal is to learn from training examples a highly nonlinear classifier to differentiate between face and nonface patterns in a high dimensional space. The results clearly demonstrate the promises made by FloatBoost over AdaBoost.


Parametric Mixture Models for Multi-Labeled Text

Neural Information Processing Systems

We propose probabilistic generative models, called parametric mixture models (PMMs), for multiclass, multi-labeled text categorization problem. Conventionally, the binary classification approach has been employed, in which whether or not text belongs to a category is judged by the binary classifier for every category. In contrast, our approach can simultaneously detect multiple categories of text using PMMs. We derive efficient learning and prediction algorithms for PMMs. We also empirically show that our method could significantly outperform the conventional binary methods when applied to multi-labeled text categorization using real World Wide Web pages.


Extracting Relevant Structures with Side Information

Neural Information Processing Systems

The problem of extracting the relevant aspects of data, in face of multiple conflicting structures, is inherent to modeling of complex data. Extracting structure in one random variable that is relevant for another variable has been principally addressed recently via the information bottleneck method [15]. However, such auxiliary variables often contain more information than is actually required due to structures that are irrelevant for the task. In many other cases it is in fact easier to specify what is irrelevant than what is, for the task at hand. Identifying the relevant structures, however, can thus be considerably improved by also minimizing the information about another, irrelevant, variable. In this paper we give a general formulation of this problem and derive its formal, as well as algorithmic, solution. Its operation is demonstrated in a synthetic example and in two real world problems in the context of text categorization and face images. While the original information bottleneck problem is related to rate distortion theory, with the distortion measure replaced by the relevant information, extracting relevant features while removing irrelevant ones is related to rate distortion with side information.


Critical Lines in Symmetry of Mixture Models and its Application to Component Splitting

Neural Information Processing Systems

We show the existence of critical points as lines for the likelihood function of mixture-type models. They are given by embedding of a critical point for models with less components. A sufficient condition that the critical line gives local maxima or saddle points is also derived. Based on this fact, a component-split method is proposed for a mixture of Gaussian components, and its effectiveness is verified through experiments.


Learning to Detect Natural Image Boundaries Using Brightness and Texture

Neural Information Processing Systems

The goal of this work is to accurately detect and localize boundaries in natural scenes using local image measurements. We formulate features that respond to characteristic changes in brightness and texture associated with natural boundaries. In order to combine the information from these features in an optimal way, a classifier is trained using human labeled images as ground truth. We present precision-recall curves showing that the resulting detector outperforms existing approaches.


Efficient Learning Equilibrium

Neural Information Processing Systems

We introduce efficient learning equilibrium (ELE), a normative approach to learning in non cooperative settings. In ELE, the learning algorithms themselves are required to be in equilibrium. In addition, the learning algorithms arrive at a desired value after polynomial time, and deviations from a prescribed ELE become irrational after polynomial time. We prove the existence of an ELE in the perfect monitoring setting, where the desired value is the expected payoff in a Nash equilibrium. We also show that an ELE does not always exist in the imperfect monitoring case. Yet, it exists in the special case of common-interest games. Finally, we extend our results to general stochastic games.


Learning to Detect Natural Image Boundaries Using Brightness and Texture

Neural Information Processing Systems

The goal of this work is to accurately detect and localize boundaries in natural scenes using local image measurements. We formulate features that respond to characteristic changes in brightness and texture associated with natural boundaries. In order to combine the information from these features in an optimal way, a classifier is trained using human labeled images as ground truth. We present precision-recall curves showing that the resulting detector outperforms existing approaches.