Agentic AI marks a major shift in how autonomous systems reason, plan, and execute multi-step tasks. Unlike traditional single model prompting, agentic workflows integrate multiple specialized agents with different Large Language Models(LLMs), tool-augmented capabilities, orchestration logic, and external system interactions to form dynamic pipelines capable of autonomous decision-making and action. As adoption accelerates across industry and research, organizations face a central challenge: how to design, engineer, and operate production-grade agentic AI workflows that are reliable, observable, maintainable, and aligned with safety and governance requirements. This paper provides a practical, end-to-end guide for design-Email addresses: cmedawer@odu.edu We introduce a structured engineering lifecycle encompassing workflow decomposition, multi-agent design patterns, Model Context Protocol(MCP), and tool integration, deterministic orchestration, Responsible-AI considerations, and environment-aware deployment strategies. We then present nine core best practices for engineering production-grade agentic AI workflows, including tool-first design over MCP, pure-function invocation, single-tool and single-responsibility agents, externalized prompt management, Responsible-AI-aligned model-consortium design, clean separation between workflow logic and MCP servers, containerized deployment for scalable operations, and adherence to the Keep it Simple, Stupid (KISS) principle to maintain simplicity and robustness. To demonstrate these principles in practice, we present a comprehensive case study: a multimodal news-analysis and media-generation workflow. By combining architectural guidance, operational patterns, and practical implementation insights, this paper offers a foundational reference to build robust, extensible, and production-ready agentic AI workflows. Introduction The rapid advancement of Large Language Models (LLMs) [1, 2], Vision-Language Models (VLMs) [3, 4, 5], and tool-augmented reasoning has laid the foundation for a new paradigm in automation: agentic AI [6, 7]. Traditional LLM interactions follow a simple pattern in which a human provides a prompt and the model generates a response (as illustrated in the top half of Figure 1).

Abstract--This paper proposes a hardware-aware intrusion detection system (IDS) for Internet of Things (IoT) and Industrial IoT (IIoT) networks; it targets scenarios where classification is essential for fast, privacy-preserving, and resource-efficient threat detection. The goal is to optimize both tree-based machine learning (ML) models and compact deep neural networks (DNNs) within strict edge-device constraints. This allows for a fair comparison and reveals trade-offs between model families. We apply constrained grid search for tree-based classifiers and hardware-aware neural architecture search (HW-NAS) for 1D convolutional neural networks (1D-CNNs). Evaluation on the Edge-IIoTset benchmark shows that selected models meet tight flash, RAM, and compute limits: LightGBM achieves 95.3% accuracy using 75 KB flash and 1.2 K operations, while the HW-NAS-optimized CNN reaches 97.2% with 190 KB flash and 840 K floating-point operations (FLOPs). We deploy the full pipeline on a Raspberry Pi 3 B+, confirming that tree-based models operate within 30 ms and that CNNs remain suitable when accuracy outweighs latency. The widespread deployment of Internet of Things (IoT) systems has expanded the attack surface of modern networks, which now include critical infrastructure and operational environments vulnerable to advanced cyber threats [1], [2].

AI agent-based systems are becoming increasingly integral to modern software architectures, enabling autonomous decision-making, dynamic task execution, and multimodal interactions through large language models (LLMs). However, these systems introduce novel and evolving security challenges, including prompt injection attacks, context poisoning, model manipulation, and opaque agent-to-agent communication, that are not effectively captured by traditional threat modeling frameworks. In this paper, we introduce ASTRIDE, an automated threat modeling platform purpose-built for AI agent-based systems. ASTRIDE extends the classical STRIDE framework by introducing a new threat category, A for AI Agent-Specific Attacks, which encompasses emerging vulnerabilities such as prompt injection, unsafe tool invocation, and reasoning subversion, unique to agent-based applications. To automate threat modeling, ASTRIDE combines a consortium of fine-tuned vision-language models (VLMs) with the OpenAI-gpt-oss reasoning LLM to perform end-to-end analysis directly from visual agent architecture diagrams, such as data flow diagrams(DFDs). LLM agents orchestrate the end-to-end threat modeling automation process by coordinating interactions between the VLM consortium and the reasoning LLM. Our evaluations demonstrate that ASTRIDE provides accurate, scalable, and explainable threat modeling for next-generation intelligent systems. To the best of our knowledge, ASTRIDE is the first framework to both extend STRIDE with AI-specific threats and integrate fine-tuned VLMs with a reasoning LLM to fully automate diagram-driven threat modeling in AI agent-based applications.

Abstract--The widespread adoption of complex machine learning models in high-stakes domains has brought the "black-box" problem to the forefront of responsible AI research. This paper aims at addressing this issue by improving the Explainable Boosting Machine (EBM), a state-of-the-art glassbox model that delivers both high accuracy and complete transparency. The paper outlines three distinct enhancement methodologies: targeted hyperparameter optimization with Bayesian methods, the implementation of a custom multi-objective function for fairness for hyperparameter optimization, and a novel self-supervised pre-training pipeline for cold-start scenarios. All three methodologies are evaluated across standard benchmark datasets, including the Adult Income, Credit Card Fraud Detection, and UCI Heart Disease datasets. The analysis indicates that while the tuning process yielded marginal improvements in the primary ROC AUC metric, it led to a subtle but important shift in the model's decision-making behavior, demonstrating the value of a multi-faceted evaluation beyond a single performance score. This work is positioned as a critical step toward developing machine learning systems that are not only accurate but also robust, equitable, and transparent, meeting the growing demands of regulatory and ethical compliance. A. The Black-Box Problem in High-Stakes Domains The remarkable surge in the performance of machine learning models has led to their pervasive adoption across a multitude of domains, from retail and finance to medicine and judicial systems. Complex, high-performing models, such as deep neural networks and ensemble methods like Random Forest and XGBoost, have become the de facto standard for many tasks.

Self-supervised representation learning, particularly through contrastive methods like TS2Vec, has advanced the analysis of time series data. However, these models often falter in forecasting tasks because their objective functions prioritize instance discrimination over capturing the deterministic patterns, such as seasonality and trend, that are critical for accurate prediction. This paper introduces TS2Vec-Ensemble, a novel hybrid framework designed to bridge this gap. Our approach enhances the powerful, implicitly learned dynamics from a pretrained TS2Vec encoder by fusing them with explicit, engineered time features that encode periodic cycles. This fusion is achieved through a dual-model ensemble architecture, where two distinct regression heads -- one focused on learned dynamics and the other on seasonal patterns -- are combined using an adaptive weighting scheme. The ensemble weights are optimized independently for each forecast horizon, allowing the model to dynamically prioritize short-term dynamics or long-term seasonality as needed. We conduct extensive experiments on the ETT benchmark datasets for both univariate and multivariate forecasting. The results demonstrate that TS2Vec-Ensemble consistently and significantly outperforms the standard TS2Vec baseline and other state-of-the-art models, validating our hypothesis that a hybrid of learned representations and explicit temporal priors is a superior strategy for long-horizon time series forecasting.

Neonates are highly susceptible to seizures, often leading to short or long-term neurological impairments. However, clinical manifestations of neonatal seizures are subtle and often lead to misdiagnoses. This increases the risk of prolonged, untreated seizure activity and subsequent brain injury. Continuous video electroencephalogram (cEEG) monitoring is the gold standard for seizure detection. However, this is an expensive evaluation that requires expertise and time. In this study, we propose a convolutional neural network-based model for early prediction of neonatal seizures by distinguishing between interictal and preictal states of the EEG. Our model is patient-independent, enabling generalization across multiple subjects, and utilizes mel-frequency cepstral coefficient matrices extracted from multichannel EEG and electrocardiogram (ECG) signals as input features. Trained and validated on the Helsinki neonatal EEG dataset with 10-fold cross-validation, the proposed model achieved an average accuracy of 97.52%, sensitivity of 98.31%, specificity of 96.39%, and F1-score of 97.95%, enabling accurate seizure prediction up to 30 minutes before onset. The inclusion of ECG alongside EEG improved the F1-score by 1.42%, while the incorporation of an attention mechanism yielded an additional 0.5% improvement. To enhance transparency, we incorporated SHapley Additive exPlanations (SHAP) as an explainable artificial intelligence method to interpret the model and provided localization of seizure focus using scalp plots. The overall results demonstrate the model's potential for minimally supervised deployment in neonatal intensive care units, enabling timely and reliable prediction of neonatal seizures, while demonstrating strong generalization capability across unseen subjects through transfer learning.

The emergence of Agentic AI is fundamentally transforming how software is designed, developed, and maintained. Traditional software development methodologies such as Agile, Kanban, ShapeUp, etc, were originally designed for human-centric teams and are increasingly inadequate in environments where autonomous AI agents contribute to planning, coding, testing, and continuous learning. To address this methodological gap, we present "Agentsway" a novel software development framework designed for ecosystems where AI agents operate as first-class collaborators. Agentsway introduces a structured lifecycle centered on human orchestration, and privacy-preserving collaboration among specialized AI agents. The framework defines distinct roles for planning, prompting, coding, testing, and fine-tuning agents, each contributing to iterative improvement and adaptive learning throughout the development process. By integrating fine-tuned LLMs that leverage outputs and feedback from different agents throughout the development cycle as part of a retrospective learning process, Agentsway enhances domain-specific reasoning, and explainable decision-making across the entire software development lifecycle. Responsible AI principles are further embedded across the agents through the coordinated use of multiple fine-tuned LLMs and advanced reasoning models, ensuring balanced, transparent, and accountable decision-making. This work advances software engineering by formalizing agent-centric collaboration, integrating privacy-by-design principles, and defining measurable metrics for productivity and trust. Agentsway represents a foundational step toward the next generation of AI-native, self-improving software development methodologies. To the best of our knowledge, this is the first research effort to introduce a dedicated methodology explicitly designed for AI agent-based software engineering teams.

Intelligent analysis of medical imaging plays a crucial role in assisting clinical diagnosis, especially for identifying subtle pathological features. This paper introduces a novel multi-branch ConvNeXt architecture designed specifically for the nuanced challenges of medical image analysis. While applied here to the specific problem of COVID-19 diagnosis, the methodology offers a generalizable framework for classifying a wide range of pathologies from CT scans. The proposed model incorporates a rigorous end-to-end pipeline, from meticulous data preprocessing and augmentation to a disciplined two-phase training strategy that leverages transfer learning effectively. The architecture uniquely integrates features extracted from three parallel branches: Global Average Pooling, Global Max Pooling, and a new Attention-weighted Pooling mechanism. The model was trained and validated on a combined dataset of 2,609 CT slices derived from two distinct datasets. Experimental results demonstrate a superior performance on the validation set, achieving a final ROC-AUC of 0.9937, a validation accuracy of 0.9757, and an F1-score of 0.9825 for COVID-19 cases, outperforming all previously reported models on this dataset. These findings indicate that a modern, multi-branch architecture, coupled with careful data handling, can achieve performance comparable to or exceeding contemporary state-of-the-art models, thereby proving the efficacy of advanced deep learning techniques for robust medical diagnostics.

Abstract--GraphQL's flexibility, while beneficial for efficient data fetching, introduces unique security vulnerabilities that traditional API security mechanisms often fail to address. Malicious GraphQL queries can exploit the language's dynamic nature, leading to denial-of-service attacks, data exfiltration through injection, and other exploits. This paper presents a novel, AI-driven approach for real-time detection of malicious GraphQL queries. Our method combines static analysis with machine learning techniques, including Large Language Models (LLMs) for dynamic schema-based configuration, Sentence Transformers (SBERT and Doc2V ec) for contextual embedding of query payloads, and Convolutional Neural Networks (CNNs), Random Forests, and Multilayer Perceptrons for classification. We detail the system architecture, implementation strategies optimized for production environments (including ONNX Runtime optimization and parallel processing), and evaluate the performance of our detection models and the overall system under load. Results demonstrate high accuracy in detecting various threats, including SQL injection, OS command injection, and XSS exploits, alongside effective mitigation of DoS and SSRF attempts. This research contributes a robust and adaptable solution for enhancing GraphQL API security. The adoption of GraphQL has grown due to its efficiency in allowing clients to request specific data, which optimizes data transfer.

Magnetic Resonance Imaging (MRI) is a critical tool in modern medical diagnostics, yet its prolonged acquisition time remains a critical limitation, especially in time-sensitive clinical scenarios. While undersampling strategies can accelerate image acquisition, they often result in image artifacts and degraded quality. Recent diffusion models have shown promise for reconstructing high-fidelity images from undersampled data by learning powerful image priors; however, most existing approaches either (i) rely on unsupervised score functions without paired supervision or (ii) apply data consistency only as a post-processing step. In this work, we introduce a conditional denoising diffusion framework with iterative data-consistency correction, which differs from prior methods by embedding the measurement model directly into every reverse diffusion step and training the model on paired undersampled-ground truth data. This hybrid design bridges generative flexibility with explicit enforcement of MRI physics. Experiments on the fastMRI dataset demonstrate that our framework consistently outperforms recent state-of-the-art deep learning and diffusion-based methods in SSIM, PSNR, and LPIPS, with LPIPS capturing perceptual improvements more faithfully. These results demonstrate that integrating conditional supervision with iterative consistency updates yields substantial improvements in both pixel-level fidelity and perceptual realism, establishing a principled and practical advance toward robust, accelerated MRI reconstruction.