Clinical data usually cannot be freely distributed due to their highly confidential nature and this hampers the development of machine learning in the healthcare domain. One way to mitigate this problem is by generating realistic synthetic datasets using generative adversarial networks (GANs). However, GANs are known to suffer from mode collapse thus creating outputs of low diversity. This lowers the quality of the synthetic healthcare data, and may cause it to omit patients of minority demographics or neglect less common clinical practices. In this paper, we extend the classic GAN setup with an additional variational autoencoder (VAE) and include an external memory to replay latent features observed from the real samples to the GAN generator. Using antiretroviral therapy for human immunodeficiency virus (ART for HIV) as a case study, we show that our extended setup overcomes mode collapse and generates a synthetic dataset that accurately describes severely imbalanced class distributions commonly found in real-world clinical variables. In addition, we demonstrate that our synthetic dataset is associated with a very low patient disclosure risk, and that it retains a high level of utility from the ground truth dataset to support the development of downstream machine learning algorithms.

If business wants to use AI at scale, adhering to the technical guidelines for responsible AI development isn't enough. It must obtain society's explicit approval to deploy the technology. Six years ago, in March 2016, Microsoft Corporation launched an experimental AI-based chatbot, TayTweets, whose Twitter handle was @TayandYou. Tay, an acronym for "thinking about you," mimicked a 19-year-old American girl online, so the digital giant could showcase the speed at which AI can learn when it interacts with human beings. Living up to its description as "AI with zero chill," Tay started off replying cheekily to Twitter users and turning photographs into memes. Some topics were off limits, though; Microsoft had trained Tay not to comment on societal issues such as Black Lives Matter. Soon enough, a group of Twitter users targeted Tay with a barrage of tweets about controversial issues such as the Holocaust and Gamergate. They goaded the chatbot into replying with racist and sexually charged responses, exploiting its repeat-after-me capability. Realizing that Tay was reacting like IBM's Watson, which started using profanity after perusing the online Urban Dictionary, Microsoft was quick to delete the first inflammatory tweets. Less than 16 hours and more than 100,000 tweets later, the digital giant shut down Tay.

The present work develops ANAKIN: an Artificial iNtelligence bAsed model for (radiation induced) cell KIlliNg prediction. ANAKIN is trained and tested over 513 cell survival experiments with different types of radiation contained in the publicly available PIDE database. We show how ANAKIN accurately predicts several relevant biological endpoints over a wide broad range on ions beams and for a high number of cell--lines. We compare the prediction of ANAKIN to the only two radiobiological model for RBE prediction used in clinics, that is the Microdosimetric Kinetic Model (MKM) and the Local Effect Model (LEM version III), showing how ANAKIN has higher accuracy over the all considered biological endpoints. At last, via modern techniques of Explainable Artificial Intelligence (XAI), we show how ANAKIN predictions can be understood and explained, highlighting how ANAKIN is in fact able to reproduce relevant well-known biological patterns, such as the overkilling effect.

Temporal graph neural network has recently received significant attention due to its wide application scenarios, such as bioinformatics, knowledge graphs, and social networks. There are some temporal graph neural networks that achieve remarkable results. However, these works focus on future event prediction and are performed under the assumption that all historical events are observable. In real-world applications, events are not always observable, and estimating event time is as important as predicting future events. In this paper, we propose MTGN, a missing event-aware temporal graph neural network, which uniformly models evolving graph structure and timing of events to support predicting what will happen in the future and when it will happen.MTGN models the dynamic of both observed and missing events as two coupled temporal point processes, thereby incorporating the effects of missing events into the network. Experimental results on several real-world temporal graphs demonstrate that MTGN significantly outperforms existing methods with up to 89% and 112% more accurate time and link prediction. Code can be found on https://github.com/HIT-ICES/TNNLS-MTGN.

For our course project, we aim to reverse the roles of the computer and human, such that the computer will act as an answerer and a human as a questioner. In the past, no such study has been conducted as this problem presented sophisticated challenges of Natural Language Inference and Textual Entailment. However, with the advent of transformer-based machine learning techniques such as BERT [1], RoBERTa [2], GPT-2 [3], and datasets such as BoolQ [4], such a model can be constructed. As this problem has not been formally defined, our goal is to formalize it and present preliminary results regarding the same. Furthermore, while there are several pre-trained question-answering models that select the start and end points of a corpus containing an answer, a simple yes/no answering task is surprisingly challenging and complex. A model for such a task would have to examine entailment as well as investigate if the corpus makes a positive answer to the question unlikely, even if it doesn't directly state a negative answer [4]. Our reverse Akinator model could be used for any sort of factual checker to examine whether a statement is true or not, given a knowledge corpus.

ChatGPT was hailed as one 2022's most impressive technological innovations upon its release last November. The powerful artificial intelligence (AI) chatbot can generate text on almost any topic or theme, from a Shakespearean sonnet reimagined in the style of Megan Thee Stallion, to complex mathematical theorems described in language a 5 year old can understand. Within a week, it had more than a million users. ChatGPT's creator, OpenAI, is now reportedly in talks with investors to raise funds at a $29 billion valuation, including a potential $10 billion investment by Microsoft. That would make OpenAI, which was founded in San Francisco in 2015 with the aim of building superintelligent machines, one of the world's most valuable AI companies.

Clearly, such an imbalance is undesirable, putting those who do not use English at a disadvantage. In this article, we highlight some of the work and initiatives being carried out on low-resource languages. Africa is one of the most linguistically diverse regions in the world. Despite this, African languages are barely represented in technology and research. Lanfrica aims to mitigate the difficulty encountered in the discovery of African language resources by creating a centralised hub.

With the increasing prevalence of scalable file systems in the context of High Performance Computing (HPC), the importance of accurate anomaly detection on runtime logs is increasing. But as it currently stands, many state-of-the-art methods for log-based anomaly detection, such as DeepLog, have encountered numerous challenges when applied to logs from many parallel file systems (PFSes), often due to their irregularity and ambiguity in time-based log sequences. To circumvent these problems, this study proposes ClusterLog, a log pre-processing method that clusters the temporal sequence of log keys based on their semantic similarity. By grouping semantically and sentimentally similar logs, this approach aims to represent log sequences with the smallest amount of unique log keys, intending to improve the ability of a downstream sequence-based model to effectively learn the log patterns. The preliminary results of ClusterLog indicate not only its effectiveness in reducing the granularity of log sequences without the loss of important sequence information but also its generalizability to different file systems' logs.

Obtaining accurate ground and low-lying excited states of electronic systems is crucial in a multitude of important applications. One ab initio method for solving the Schr\"odinger equation that scales favorably for large systems is variational quantum Monte Carlo (QMC). The recently introduced deep QMC approach uses ansatzes represented by deep neural networks and generates nearly exact ground-state solutions for molecules containing up to a few dozen electrons, with the potential to scale to much larger systems where other highly accurate methods are not feasible. In this paper, we extend one such ansatz (PauliNet) to compute electronic excited states. We demonstrate our method on various small atoms and molecules and consistently achieve high accuracy for low-lying states. To highlight the method's potential, we compute the first excited state of the much larger benzene molecule, as well as the conical intersection of ethylene, with PauliNet matching results of more expensive high-level methods.

Foundation models have shown impressive adaptation and scalability in supervised and self-supervised learning problems, but so far these successes have not fully translated to reinforcement learning (RL). In this work, we demonstrate that training an RL agent at scale leads to a general in-context learning algorithm that can adapt to open-ended novel embodied 3D problems as quickly as humans. In a vast space of held-out environment dynamics, our adaptive agent (AdA) displays on-the-fly hypothesis-driven exploration, efficient exploitation of acquired knowledge, and can successfully be prompted with first-person demonstrations. Adaptation emerges from three ingredients: (1) meta-reinforcement learning across a vast, smooth and diverse task distribution, (2) a policy parameterised as a large-scale attention-based memory architecture, and (3) an effective automated curriculum that prioritises tasks at the frontier of an agent's capabilities. We demonstrate characteristic scaling laws with respect to network size, memory length, and richness of the training task distribution. We believe our results lay the foundation for increasingly general and adaptive RL agents that perform well across ever-larger open-ended domains.