Prescription contraceptives play a critical role in supporting women's reproductive health. With nearly 50 million women in the United States using contraceptives, understanding the factors that drive contraceptives selection and switching is of significant interest. However, many factors related to medication switching are often only captured in unstructured clinical notes and can be difficult to extract. Here, we evaluate the zero-shot abilities of a recently developed large language model, GPT-4 (via HIPAA-compliant Microsoft Azure API), to identify reasons for switching between classes of contraceptives from the UCSF Information Commons clinical notes dataset. We demonstrate that GPT-4 can accurately extract reasons for contraceptive switching, outperforming baseline BERT-based models with microF1 scores of 0.849 and 0.881 for contraceptive start and stop extraction, respectively. Human evaluation of GPT-4-extracted reasons for switching showed 91.4% accuracy, with minimal hallucinations. Using extracted reasons, we identified patient preference, adverse events, and insurance as key reasons for switching using unsupervised topic modeling approaches. Notably, we also showed using our approach that "weight gain/mood change" and "insurance coverage" are disproportionately found as reasons for contraceptive switching in specific demographic populations. Our code and supplemental data are available at https://github.com/BMiao10/contraceptive-switching.

The second-order properties of the training loss have a massive impact on the optimization dynamics of deep learning models. Fort & Scherlis (2019) discovered that a high positive curvature and local convexity of the loss Hessian are associated with highly trainable initial points located in a region coined the "Goldilocks zone". Only a handful of subsequent studies touched upon this relationship, so it remains largely unexplained. In this paper, we present a rigorous and comprehensive analysis of the Goldilocks zone for homogeneous neural networks. In particular, we derive the fundamental condition resulting in non-zero positive curvature of the loss Hessian and argue that it is only incidentally related to the initialization norm, contrary to prior beliefs. Further, we relate high positive curvature to model confidence, low initial loss, and a previously unknown type of vanishing cross-entropy loss gradient. To understand the importance of positive curvature for trainability of deep networks, we optimize both fully-connected and convolutional architectures outside the Goldilocks zone and analyze the emergent behaviors. We find that strong model performance is not necessarily aligned with the Goldilocks zone, which questions the practical significance of this concept.

The extraordinary advancement in Generative Artificial Intelligence (GenAI) has caused a transformative shift in our approach to complex tasks incorporating various modalities such as text, audio, video, and image generation. GenAI, as a broad category, excels at creating synthetic data that can closely mimic real-world phenomena, showcasing its prowess in diverse creative applications. In text generation, models like OpenAI's GPT (Generative Pre-trained Transformer) [OpenAI, 2023] are revolutionizing how society writes. These models, trained on massive corpora of text data, exhibit an impressive ability to understand context, generate coherent paragraphs, and even complete sentences in a very consistent way [Roumeliotis and Tselikas, 2023]. The ability to produce fluent and relevant textual content has established applications in natural language processing, content creation, and even automated writing [Huang and Tan, 2023]. Audio generation models, exemplified by technologies such as Tacotron [Wang et al., 2017] and WaveNet [Oord et al., 2016], have significantly advanced our ability to synthesize realistic speech patterns. These models take advantage of deep neural networks to capture the intricacies of human speech, producing natural-sounding voices and musical compositions with nuanced variations in tone, pitch, and rhythm [Ning et al., 2019]. Image generation, a focal point of our discussion, has witnessed the evolution of models such as DALL-E [Betker et al., 2023, Ramesh et al., 2021], MidJourney [mid, 2022], and Stable Diffusion [Rombach et al., 2022], which can generate diverse and intricate images from textual prompts.

Adaptive gradient optimizers like Adam(W) are the default training algorithms for many deep learning architectures, such as transformers. Their diagonal preconditioner is based on the gradient outer product which is incorporated into the parameter update via a square root. While these methods are often motivated as approximate second-order methods, the square root represents a fundamental difference. In this work, we investigate how the behavior of adaptive methods changes when we remove the root, i.e. strengthen their second-order motivation. Surprisingly, we find that such square-root-free adaptive methods close the generalization gap to SGD on convolutional architectures, while maintaining their root-based counterpart's performance on transformers. The second-order perspective also has practical benefits for the development of adaptive methods with non-diagonal preconditioner. In contrast to root-based counterparts like Shampoo, they do not require numerically unstable matrix square roots and therefore work well in low precision, which we demonstrate empirically. This raises important questions regarding the currently overlooked role of adaptivity for the success of adaptive methods.

There is a sensory gulf between the Earth that humans inhabit and the digital realms in which modern AI agents are created. To develop AI agents that can sense, think, and act as flexibly as humans in real-world settings, it is imperative to bridge the realism gap between the digital and physical worlds. How can we embody agents in an environment as rich and diverse as the one we inhabit, without the constraints imposed by real hardware and control? Towards this end, we introduce V-IRL: a platform that enables agents to scalably interact with the real world in a virtual yet realistic environment. Our platform serves as a playground for developing agents that can accomplish various practical tasks and as a vast testbed for measuring progress in capabilities spanning perception, decision-making, and interaction with real-world data across the entire globe.

In the face of uncertainty, the ability to seek information is of fundamental importance. In many practical applications, such as medical diagnosis and troubleshooting, the information needed to solve the task is not initially given, and has to be actively sought by asking follow-up questions (for example, a doctor asking a patient for more details about their symptoms). In this work, we introduce Uncertainty of Thoughts (UoT), an algorithm to augment large language models with the ability to actively seek information by asking effective questions. UoT combines 1) an uncertainty-aware simulation approach which enables the model to simulate possible future scenarios and how likely they are to occur, 2) uncertainty-based rewards motivated by information gain which incentivizes the model to seek information, and 3) a reward propagation scheme to select the optimal question to ask in a way that maximizes the expected reward. In experiments on medical diagnosis, troubleshooting and the '20 Questions' game, UoT achieves an average performance improvement of 57.8% in the rate of successful task completion across multiple LLMs compared with direct prompting, and also improves efficiency (i.e., the number of questions needed to complete the task).

We investigate the training dynamics of two-layer neural networks when learning multi-index target functions. We focus on multi-pass gradient descent (GD) that reuses the batches multiple times and show that it significantly changes the conclusion about which functions are learnable compared to single-pass gradient descent. In particular, multi-pass GD with finite stepsize is found to overcome the limitations of gradient flow and single-pass GD given by the information exponent (Ben Arous et al., 2021) and leap exponent (Abbe et al., 2023) of the target function. We show that upon re-using batches, the network achieves in just two time steps an overlap with the target subspace even for functions not satisfying the staircase property (Abbe et al., 2021). We characterize the (broad) class of functions efficiently learned in finite time. The proof of our results is based on the analysis of the Dynamical Mean-Field Theory (DMFT). We further provide a closed-form description of the dynamical process of the low-dimensional projections of the weights, and numerical experiments illustrating the theory.

Learning and predicting the performance of given software configurations are of high importance to many software engineering activities. While configurable software systems will almost certainly face diverse running environments (e.g., version, hardware, and workload), current work often either builds performance models under a single environment or fails to properly handle data from diverse settings, hence restricting their accuracy for new environments. In this paper, we target configuration performance learning under multiple environments. We do so by designing SeMPL - a meta-learning framework that learns the common understanding from configurations measured in distinct (meta) environments and generalizes them to the unforeseen, target environment. What makes it unique is that unlike common meta-learning frameworks (e.g., MAML and MetaSGD) that train the meta environments in parallel, we train them sequentially, one at a time. The order of training naturally allows discriminating the contributions among meta environments in the meta-model built, which fits better with the characteristic of configuration data that is known to dramatically differ between different environments. Through comparing with 15 state-of-the-art models under nine systems, our extensive experimental results demonstrate that SeMPL performs considerably better on 89% of the systems with up to 99% accuracy improvement, while being data-efficient, leading to a maximum of 3.86x speedup. All code and data can be found at our repository: https://github.com/ideas-labo/SeMPL.

Instruction tuning has emerged as a prominent methodology for teaching Large Language Models (LLMs) to follow instructions. However, current instruction datasets predominantly cater to English or are derived from English-dominated LLMs, resulting in inherent biases toward Western culture. This bias significantly impacts the linguistic structures of non-English languages such as Arabic, which has a distinct grammar reflective of the diverse cultures across the Arab region. This paper addresses this limitation by introducing CIDAR: https://hf.co/datasets/arbml/CIDAR, the first open Arabic instruction-tuning dataset culturally-aligned by human reviewers. CIDAR contains 10,000 instruction and output pairs that represent the Arab region. We discuss the cultural relevance of CIDAR via the analysis and comparison to other models fine-tuned on other datasets. Our experiments show that CIDAR can help enrich research efforts in aligning LLMs with the Arabic culture. All the code is available at https://github.com/ARBML/CIDAR.

We examine the impact of homograph attacks on the Sentiment Analysis (SA) task of different Arabic dialects from the Maghreb North-African countries. Homograph attacks result in a 65.3% decrease in transformer classification from an F1-score of 0.95 to 0.33 when data is written in "Arabizi". The goal of this study is to highlight LLMs weaknesses' and to prioritize ethical and responsible Machine Learning.