Systems & Languages: Overviews

Cyc and the Big C: Reading that Produces and Uses Hypotheses about Complex Molecular Biology Mechanisms

AAAI Conferences

Systems biology, the study of the intricate, ramified, com-plex and interacting mechanisms underlying life, often proves too complex for unaided human understanding, even by groups of people working together. This difficulty is ex-acerbated by the high volume of publications in molecular biology. The Big C (‘C’ for Cyc) is a system designed to (semi-)automatically acquire, integrate, and use complex mechanism models, specifically related to cancer biology, via automated reading and a hyper-detailed refinement pro-cess resting on Cyc’s logical representations and powerful inference mechanisms. We aim to assist cancer research and treatment by achieving elements of biologist-level reason-ing, but with the scale and attention to detail that only com-puter implementations can provide.

Noise-Enhanced Associative Memories

Neural Information Processing Systems

Recent advances in associative memory design through structured pattern sets and graph-based inference algorithms have allowed reliable learning and recall of an exponential number of patterns. Although these designs correct external errors in recall, they assume neurons that compute noiselessly, in contrast to the highly variable neurons in hippocampus and olfactory cortex. Here we consider associative memories with noisy internal computations and analytically characterize performance. As long as the internal noise level is below a specified threshold, the error probability in the recall phase can be made exceedingly small. More surprisingly, we show that internal noise actually improves the performance of the recall phase. Computational experiments lend additional support to our theoretical analysis. This work suggests a functional benefit to noisy neurons in biological neuronal networks.

Distributed Problem Solving

AI Magazine

Distributed problem solving is a subfield within multiagent systems, where agents are assumed to be part of a team and collaborate with each other to reach a common goal. In this article, we illustrate the motivations for distributed problem solving and provide an overview of two distributed problem solving models, namely distributed constraint satisfaction problems (DCSPs) and distributed constraint optimization problems (DCOPs), and some of their algorithms.

Multiagent Systems: A Modern Approach to Distributed Artificial Intelligence

AI Magazine

As the title indicates, Multiagent Systems: A Modern Approach to Distributed Artificial Intelligence covers the design and development of multiagent and distributed AI systems. The purpose of this book is to provide a comprehensive overview of the field. It is an excellent collection of closely related papers that provides a wonderful introduction to multiagent systems and distributed AI.