Bacteria


A new machine learning tool could flag dangerous bacteria before they cause an outbreak

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A new machine learning tool that can detect whether emerging strains of the bacterium, Salmonella are more likely to cause dangerous bloodstream infections rather than food poisoning has been developed. The tool, created by a scientist at the Wellcome Sanger Institute and her collaborators at the University of Otago, New Zealand and the Helmholtz Institute for RNA-based Infection Research, a site of the Helmholtz Centre for Infection Research, Germany, greatly speeds up the process for identifying the genetic changes underlying new invasive types of Salmonella that are of public health concern. Reported today (8 May) in PLOS Genetics, the machine learning tool could be useful for flagging dangerous bacteria before they cause an outbreak, from hospital wards to a global scale. As the cost of genomic sequencing falls, scientists around the world are using genetics to better understand the bacteria causing infections, how diseases spread, how bacteria gain resistance to drugs, and which strains of bacteria may cause outbreaks. However, current methods to identify the genetic adaptations in emerging strains of bacteria behind an outbreak are time-consuming and often involve manually comparing the new strain to an older reference collection.


Machine learning flags emerging pathogens: A new machine learning tool could flag dangerous bacteria before they cause an outbreak, from hospital wards to a global scale

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Reported today (8 May) in PLOS Genetics, the machine learning tool could be useful for flagging dangerous bacteria before they cause an outbreak, from hospital wards to a global scale. As the cost of genomic sequencing falls, scientists around the world are using genetics to better understand the bacteria causing infections, how diseases spread, how bacteria gain resistance to drugs, and which strains of bacteria may cause outbreaks. However, current methods to identify the genetic adaptations in emerging strains of bacteria behind an outbreak are time-consuming and often involve manually comparing the new strain to an older reference collection. The group of bacteria known as Salmonella includes many different types that vary in the severity of the disease they cause. Some types cause food poisoning, known as gastrointestinal Salmonella, whereas others cause severe disease by spreading beyond the gut, for example Salmonella Typhi which causes typhoid fever.


Machine Learning Flags Emerging Pathogens

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A new machine learning tool that can detect whether emerging strains of the bacterium, Salmonella are more likely to cause dangerous bloodstream infections rather than food poisoning has been developed. The tool, created by a scientist at the Wellcome Sanger Institute and her collaborators at the University of Otago, New Zealand and the Helmholtz Institute for RNA-based Infection Research, a site of the Helmholtz Centre for Infection Research, Germany, greatly speeds up the process for identifying the genetic changes underlying new invasive types of Salmonella that are of public health concern. Reported today (8 May) in PLOS Genetics, the machine learning tool could be useful for flagging dangerous bacteria before they cause an outbreak, from hospital wards to a global scale. As the cost of genomic sequencing falls, scientists around the world are using genetics to better understand the bacteria causing infections, how diseases spread, how bacteria gain resistance to drugs, and which strains of bacteria may cause outbreaks. However, current methods to identify the genetic adaptations in emerging strains of bacteria behind an outbreak are time-consuming and often involve manually comparing the new strain to an older reference collection.


Machine learning flags emerging pathogens

#artificialintelligence

A new machine learning tool that can detect whether emerging strains of the bacterium, Salmonella are more likely to cause dangerous bloodstream infections rather than food poisoning has been developed. The tool, created by a scientist at the Wellcome Sanger Institute and her collaborators at the University of Otago, New Zealand and the Helmholtz Institute for RNA-based Infection Research, a site of the Helmholtz Centre for Infection Research, Germany, greatly speeds up the process for identifying the genetic changes underlying new invasive types of Salmonella that are of public health concern. Reported today (8 May) in PLOS Genetics, the machine learning tool could be useful for flagging dangerous bacteria before they cause an outbreak, from hospital wards to a global scale. As the cost of genomic sequencing falls, scientists around the world are using genetics to better understand the bacteria causing infections, how diseases spread, how bacteria gain resistance to drugs, and which strains of bacteria may cause outbreaks. However, current methods to identify the genetic adaptations in emerging strains of bacteria behind an outbreak are time-consuming and often involve manually comparing the new strain to an older reference collection.



Less Than 10% of Bovine i E. coli /i Strains Affect Human Health

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Using software to compare genetic information in bacterial isolates from animals and people, researchers have predicted that less than 10% of Escherichia coli 0157:H7 strains are likely to have the potential to cause human disease. According to Nadejda Lupolova, from the University of Edinburgh, Scotland, and colleagues, "machine-learning approaches have tremendous potential to interrogate complex genome information for which specific attributes of the organism, such as disease or isolation host, are known." The researchers published the results of their study in Proceedings of the National Academy of Sciences. Although most E. coli strains live in the gastrointestinal tracts of people and animals without causing disease, infection with E. coli 0157 is associated with serious illness in people. E. coli 0157 was first identified as a cause of disease in the United States in 1982, during an investigation into an outbreak of hemorrhagic colitis.


Researchers Use Machine Learning to Detect Pathogenic Bacteria in Cattle

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A team of researchers has found a new way to detect dangerous strains of bacteria, potentially preventing outbreaks of food poisoning. The team developed a method that utilizes machine learning and tested it with isolates of Escherichia coli strains. The details are in a paper that was just published in the journal Proceedings of the National Academy of Sciences. Most strains of Escherichia coli are harmless and naturally found in the human body. There are pathogenic strains, however, and they are a rising health concern.


The Roslin Institute (University of Edinburgh) - News

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Machine learning can predict strains of bacteria likely to cause food poisoning outbreaks, research has found. The study – which focused on harmful strains of E. coli bacteria – could help public health officials to target interventions and reduce risk to human health. Researchers at the University of Edinburgh's Roslin Institute used software that compares genetic information from bacterial samples isolated from both animals and people. The software learns the DNA signatures that are associated with E. coli samples that have caused outbreaks of infection in people. It can then pick out the animal strains that have these signatures, which are therefore likely to be a threat to human health.