The discovery of processes for the synthesis of new materials involves many decisions about process design, operation, and material properties. Experimentation is crucial but as complexity increases, exploration of variables can become impractical using traditional combinatorial approaches. We describe an iterative method which uses machine learning to optimise process development, incorporating multiple qualitative and quantitative objectives. We demonstrate the method with a novel fluid processing platform for synthesis of short polymer fibers, and show how the synthesis process can be efficiently directed to achieve material and process objectives.
Good profitable customers rarely become unprofitable. It is more likely that they were unprofitable from the onset. Determining an approach to define customer value can be a complex decision. Traditionally, we use gross margin in identifying good and bad customers. For example, if your overhead costs are 25% of gross revenue, a good customer is anyone with a gross margin over 25%.
The research, which Carbon Black says looked "Beyond the Hype" found that the roles of AI and ML in preventing cyber-attacks have been met with both hope and skepticism. The vast majority (93 percent) of the 400 security researchers interviewed while conducting this research said non-malware attacks pose more of a business risk than commodity malware attacks, and more importantly that these are often not stopped by traditional anti-virus offerings. Mike Viscuso, co-founder and CTO of Carbon Black told SC Media UK: "Researchers have reported seeing an increase in the number, and sophistication, of non-malware attacks. These attacks are specifically designed to evade file-based prevention mechanisms and leverage native operating system tools to keep attackers under the radar." One respondent explained: "Most users seem to be familiar with the idea that their computer or network may have accidentally become infected with a virus, but rarely consider a person who is actually attacking them in a more proactive and targeted manner."
The first step of the partnership will see Nuritas, a biotech and R&D start-up that uses artificial intelligence and new technologies for the discovery of novel food and health ingredients, grant an exclusive royalty-based license to BASF to commercialise one of its existing peptides. A second part of the deal will focus on the discovery of new functional peptides, based on health areas that are strategically important to BASF, using Nuritas' technological expertise and AI platform. According to BASF, peptide networks of focus in the collaboration will be natural, food-derived, patented and of significant benefit to health – including peptides that bring about anti-inflammatory responses. "Cooperating with an innovative and agile start-up like Nuritas enables us to further expand our already broad portfolio of health solutions," commented Saori Dubourg, head of BASF's Nutrition & Health Business. Nuritas' unique platform combines DNA analysis and artificial intelligence (AI) to predict, unlock, and validate peptides from natural sources.
As micro-molding gives way to "nano-molding," processors will need creative answers to the problems of handling flyspeck-sized parts. Farms may replace oil wells as the source of new plastics. Biopolymers made from cornstarch or other renewable feedstocks will supple-ment petrochemical-derived polymers in a wide range of applications. What if you could change the color of every part right at the machine? Instant color changes may be part of the coming era of "mass customization." New methods of polymer production will allow custom materials to be "programmed" for individual applications. Say Hello to Nano Molding The new frontier of injection molding is "shrinking," says Carl Schiffer, managing partner at Dr. Boy GmbH in Germany. Miniaturization in electronic and medical parts will help push today's micro-molding toward "nano"-size parts. Machinery will need to evolve to meet the "nano" challenge. Shot sizes must become smaller, and screw diameters are already shrinking from the standard lower limit of 14 mm.
The industrial robotics market in the rubber and plastic industry for material handling application was valued USD 1.06 billion in 2015. The industrial robotics market in the rubber and plastic industry for assembling and the disassembling application was valued USD 480.9 million in 2015. The industrial robotics market in the rubber and plastic industry for dispensing and painting application was valued at USD 412.4 million in 2015. Manual gluing, painting, and adhesive-dispensing operations demand high precision and consistent quality.
The pods run on electricity, and are able to travel autonomously on smaller roads, such as those within a gated community or school campus. The pods look like they're going to be larger versions of the ones that already run in Abu Dhabi's cleantech business park, Masdar City -- also produced by 2getthere and SMRT back in 2010. The futuristic petrol car-free park has 10 electric pods, which seat between four and six passengers each, and the system marked its millionth passenger carried in 2014. In this video, you can see Masdar City's pods in operation, exiting their charging blocks and moving seamlessly to the next station.
Problems related to an inadequate data base of interpretation rules. The same set of production rules can suggest possible structural interpretations of 13C spectral features. Any individual 13C feature permits a great variety of st,:uctural interpretations. This paper presents an "expert system" devised to aid organic chemists in determining the structure (i.e. the arrangement of atoms and bonds) of newly isolated, naturally occurring compounds. The system exploits a data base of rules for analyzing.013
Ravanbakhsh, Siamak, Liu, Philip, Bjorndahl, Trent, Mandal, Rupasri, Grant, Jason R., Wilson, Michael, Eisner, Roman, Sinelnikov, Igor, Hu, Xiaoyu, Luchinat, Claudio, Greiner, Russell, Wishart, David S.
Many diseases cause significant changes to the concentrations of small molecules (aka metabolites) that appear in a person's biofluids, which means such diseases can often be readily detected from a person's "metabolic profile". This information can be extracted from a biofluid's NMR spectrum. Today, this is often done manually by trained human experts, which means this process is relatively slow, expensive and error-prone. This paper presents a tool, Bayesil, that can quickly, accurately and autonomously produce a complex biofluid's (e.g., serum or CSF) metabolic profile from a 1D1H NMR spectrum. This requires first performing several spectral processing steps then matching the resulting spectrum against a reference compound library, which contains the "signatures" of each relevant metabolite. Many of these steps are novel algorithms and our matching step views spectral matching as an inference problem within a probabilistic graphical model that rapidly approximates the most probable metabolic profile. Our extensive studies on a diverse set of complex mixtures, show that Bayesil can autonomously find the concentration of all NMR-detectable metabolites accurately (~90% correct identification and ~10% quantification error), in <5minutes on a single CPU. These results demonstrate that Bayesil is the first fully-automatic publicly-accessible system that provides quantitative NMR spectral profiling effectively -- with an accuracy that meets or exceeds the performance of trained experts. We anticipate this tool will usher in high-throughput metabolomics and enable a wealth of new applications of NMR in clinical settings. Available at http://www.bayesil.ca.