Charlottesville, VA, USA, March 31, 2021--Unbound Medicine, a leader in knowledge management solutions for healthcare, today announced a major upgrade to their end-to-end digital publishing platform. To enhance clinical decision support capabilities for professional societies and healthcare institutions, Unbound developed Unbound Intelligence (UBI)‒exclusive artificial intelligence and machine learning tools to help clinicians keep up to date with current research, as well as discover and fill knowledge gaps. Unbound Intelligence quickly analyzes large volumes of data and recommends options for next steps in patient management. While clinicians answer questions or research areas of interest on the Unbound Platform, UBI instantly filters through available resources, including the most up-to-date primary literature, to suggest closely related topics and relevant, recently published journal articles. This allows clinicians to quickly expand their reach and discover evidence-based guidance that may have otherwise gone unnoticed.
A team of University of Illinois researchers estimated the mortality costs associated with air pollution in the U.S. by developing and applying a novel machine learning-based method to estimate the life-years lost and cost associated with air pollution exposure. Scholars from the Gies College of Business at Illinois studied the causal effects of acute fine particulate matter exposure on mortality, health care use and medical costs among older Americans through Medicare data and a unique way of measuring air pollution via changes in local wind direction. The researchers--Tatyana Deryugina, Nolan Miller, David Molitor and Julian Reif--calculated that the reduction in particulate matter experienced between 1999-2013 resulted in elderly mortality reductions worth $24 billion annually by the end of that period. Garth Heutel of Georgia State University and the National Bureau of Economic Research was a co-author of the paper. "Our goal with this paper was to quantify the costs of air pollution on mortality in a particularly vulnerable population: the elderly," said Deryugina, a professor of finance who studies the health effects and distributional impact of air pollution.
In this special guest feature, Akshay Sharma, Executive Vice President of Artificial Intelligence (AI) at Sharecare, highlights advancements and impact of federated AI and edge computing for the healthcare sector as it ensures data privacy and expands the breadth of individual, organizational, and clinical knowledge. Sharma joined Sharecare in 2021 as part of its acquisition of doc.ai, the Silicon Valley-based company that accelerated digital transformation in healthcare. Sharma previously held various leadership positions including CTO, and vice president of engineering, a role in which he developed several key technologies that power mobile-based privacy products in healthcare. In addition to his role at Sharecare, Sharma serves as CTO of TEDxSanFrancisco and also is involved in initiatives to decentralize clinical trials. Sharma holds bachelor's degrees in engineering and engineering in information science from Visvesvaraya Technological University.
Gupta, Sharut, Singh, Praveer, Chang, Ken, Qu, Liangqiong, Aggarwal, Mehak, Arun, Nishanth, Vaswani, Ashwin, Raghavan, Shruti, Agarwal, Vibha, Gidwani, Mishka, Hoebel, Katharina, Patel, Jay, Lu, Charles, Bridge, Christopher P., Rubin, Daniel L., Kalpathy-Cramer, Jayashree
Model brittleness is a key concern when deploying deep learning models in real-world medical settings. A model that has high performance at one institution may suffer a significant decline in performance when tested at other institutions. While pooling datasets from multiple institutions and re-training may provide a straightforward solution, it is often infeasible and may compromise patient privacy. An alternative approach is to fine-tune the model on subsequent institutions after training on the original institution. Notably, this approach degrades model performance at the original institution, a phenomenon known as catastrophic forgetting. In this paper, we develop an approach to address catastrophic forgetting based on elastic weight consolidation combined with modulation of batch normalization statistics under two scenarios: first, for expanding the domain from one imaging system's data to another imaging system's, and second, for expanding the domain from a large multi-institutional dataset to another single institution dataset. We show that our approach outperforms several other state-of-the-art approaches and provide theoretical justification for the efficacy of batch normalization modulation. The results of this study are generally applicable to the deployment of any clinical deep learning model which requires domain expansion.
The potential of artificial intelligence to bring equity in health care has spurred significant research efforts. Racial, gender, and socioeconomic disparities have traditionally afflicted health care systems in ways that are difficult to detect and quantify. New AI technologies, however, are providing a platform for change. Regina Barzilay, the School of Engineering Distinguished Professor of AI and Health and faculty co-lead of AI for the MIT Jameel Clinic; Fotini Christia, professor of political science and director of the MIT Sociotechnical Systems Research Center; and Collin Stultz, professor of electrical engineering and computer science and a cardiologist at Massachusetts General Hospital -- discuss here the role of AI in equitable health care, current solutions, and policy implications. The three are co-chairs of the AI for Healthcare Equity Conference, taking place April 12. Q: How can AI help address racial, gender, and socioeconomic disparities in health-care systems?
The COVID pandemic may be receding, but it has left a mark on across multiple aspects of our lives. From mask mandates to travel restrictions, we chafe at some of the changes – but in the business world the use of artificial intelligence (AI) systems has dramatically expanded in the past year. This was probably inevitable – but AI brought advantages in coping with the pandemic for companies that could make use of it, and the expansion accelerated. AI has found its place in a huge range of applications, at both the front and back end of businesses. It’s prevalent in software management and data systems, as well as in communications, where AI systems filter emails and conduct robochats. And this has not been ignored by Wall Street. Analysts say that plenty of compelling investments can be found within this space. With this in mind, we’ve opened up TipRanks’ database, and pulled two stocks which are stand to benefit from AI technology. Importantly, both have amassed enough bullish calls from analysts to be given “Strong Buy” consensus ratings. Nuance Communications (NUAN) We’ll start with Nuance, a company in the communications software niche. This Massachusetts-based company offers solutions for business clients in the healthcare and customer service industries, with products that enhance speech recognition, telephone call steering systems, automated phone directories, medical transcription, and optical character recognition. It’s a full range of AI-powered, cloud communications software, applied in real time. Nuance’s flagship product, the Dragon Ambient eXperience (DAX) is marketed to the healthcare industry, where it uses AI to automate the paperwork burdens on physician practices and hospitals. This streamlines operations allow doctors more time and resources to spend on patients, and provides greater satisfaction to health care providers and users. The applications of Nuance’s product and solution lines to the current environment is clear: when the pandemic locked down so many people at home, businesses still had to maintain their customer-facing systems, and software automation, based on AI tech, made that possible with fewer personnel. Since the pandemic started last winter, the company seen its shares grow tremendously, up 205% in the last 12 months, far outpacing the overall stock market. The most recent quarterly report, for fiscal Q1, showed quarterly revenues above the forecast at $81.4 million. EPS showed a net loss, as expected, but at 27 cents the loss was a 28% sequential improvement from Q3. The company’s balance sheet is strong, with zero debt, $256 million cash on hand, and a credit facility up to $50 million. The company’s most recent quarterly report, for fiscal Q1, beat the forecasts on both the top and bottom lines. Earnings beat expectations by 11%, coming in at 20 cents per share, while revenues of $345.8 million were a modest 2% above the estimates. As a result, operating cash flow grew 22% year-over-year, to $54.6 million for the quarter. Among the bulls is 5-star analyst Daniel Ives, of Wedbush, who rates NUAN shares an Outperform (i.e. Buy), and his $65 price target implies an upside potential of ~44%. (To watch Ives’ track record, click here) "We believe Nuance overall continues to be laser focused on building a global cloud healthcare and AI driven business with growing ARR and a sustainable revenue/ earnings stream going forward with larger deals in the field as more hospital- wide deployments shift to the cloud are playing out and gaining further momentum based on our checks," Ives opined. The analyst added, "From a valuation/ SOTP perspective, we believe over time the DAX business alone could be worth between $3 billion to $4 billion to NUAN's stock as this AI next generation platform represents a potential paradigm changer for hospitals/healthcare clinics/specialists over the coming years." Ives is no outlier on Nuance, as shown by the unanimous Strong Buy analyst consensus on the stock. Nuance has received 6 recent reviews, and all are to Buy. The shares are trading for $45.20, and the $59.67 average price target suggests a 32% one-year upside. (See NUAN stock analysis on TipRanks) Dynatrace, Inc. (DT) The second AI stock we’ll look at, Dynatrace, is another cloud software company – but Dynatrace’s products are designed to power business data. The company’s AI platform brings intelligent automation to network management and cloud monitoring. DT’s platform allows for cloud automation, business analytics, digital experience, application security, applications and microservices, and infrastructure monitoring. It’s sold as a one-stop-shop for network and system managers seeking an intelligent software agent. Dynatrace’s shares have been showing consistent growth over a long term. The stock is up a robust 133% in the past 12 months, and revenues have also been growing over that period. In the most recent report, for Q3 fiscal year 2021, the company showed $182.9 million in top-line revenue, beating the forecast by ~6% and growing 27% year-over-year. EPS came in at 6 cents, flat from Q2 and far better than the break-even reported for the year-ago quarter. Three key metrics stand out in the quarterly report, and both for the right reasons. Subscription revenue grew 33% year-over-year, to reach $170.3 million, and annual recurring revenue (ARR) – which is an important predictor of future performance – grew 35% yoy and came in at $722 million. At the same time, license revenue dropped by more than 93%, to just $300,000. Taken all together, these results point toward a strong shift toward recurring cloud customers – a common trend in the software space. Needham’s 5-star analyst Jack Andrews has been closely following Dynatrace, and he believes DT’s AI products may replace incumbent tools as customers expand to additional modules. “Embedded AIOps and automation creates a compelling value proposition… Compared to competitors in the market, DT's AI Engine is embedded within its core platform and can be levered across the portfolio to deliver answers from data. Moreover, its One Agent technology automatically discovers high-fidelity data from applications and thus can map the billions of dependencies in complex environments," Andrews said. The analyst summed up, "In our view, DT is well-positioned to serve as a single source of truth that can help users trace a line between written code and business outcomes (i.e. BizDevSecOps)." Andrews named Dynatrace as a top pick, and in line with this upbeat assessment, the analyst rates the stock a Buy along with a $66 price target. Ivestors stand to pocket ~28% gain should the analyst's thesis play out. (To watch Andrews’ track record, click here) Once again, we’re looking at a stock who strong performance has inspired unanimity from the Wall Street analysts. DT shares have 13 Buy reviews, for a Strong Buy consensus rating. The stock sells for $51.76 and its $59.69 average price target suggests ~15% upside from that level. (See DT stock analysis on TipRanks) To find good ideas for AI stocks trading at attractive valuations, visit TipRanks’ Best Stocks to Buy, a newly launched tool that unites all of TipRanks’ equity insights. Disclaimer: The opinions expressed in this article are solely those of the featured analysts. The content is intended to be used for informational purposes only. It is very important to do your own analysis before making any investment.
Personal health libraries (PHLs) provide a single point of secure access to patients digital health data and enable the integration of knowledge stored in their digital health profiles with other sources of global knowledge. PHLs can help empower caregivers and health care providers to make informed decisions about patients health by understanding medical events in the context of their lives. This paper reports the implementation of a mobile health digital intervention that incorporates both digital health data stored in patients PHLs and other sources of contextual knowledge to deliver tailored recommendations for improving self-care behaviors in diabetic adults. We conducted a thematic assessment of patient functional and nonfunctional requirements that are missing from current EHRs based on evidence from the literature. We used the results to identify the technologies needed to address those requirements. We describe the technological infrastructures used to construct, manage, and integrate the types of knowledge stored in the PHL. We leverage the Social Linked Data (Solid) platform to design a fully decentralized and privacy-aware platform that supports interoperability and care integration. We provided an initial prototype design of a PHL and drafted a use case scenario that involves four actors to demonstrate how the proposed prototype can be used to address user requirements, including the construction and management of the PHL and its utilization for developing a mobile app that queries the knowledge stored and integrated into the PHL in a private and fully decentralized manner to provide better recommendations. The proposed PHL helps patients and their caregivers take a central role in making decisions regarding their health and equips their health care providers with informatics tools that support the collection and interpretation of the collected knowledge.
Artificial intelligence (AI) has potential to drive game-changing improvements for underserved communities in global health. In response, The Rockefeller Foundation and USAID partnered with the Bill and Melinda Gates Foundation to develop AI in Global Health: Defining a Collective Path Forward. Research began with a broad scan of instances where artificial intelligence is being used, tested, or considered in healthcare, resulting in a catalogue of over 240 examples. This grouping involves tools that leverage AI to monitor and assess population health, and select and target public health interventions based on AI-enabled predictive analytics. It includes AI-driven data processing methods that map the spread and burden of disease while AI predictive analytics are then used to project future disease spread of existing and possible outbreaks.
A group of hackers say they breached a massive trove of security-camera data collected by Silicon Valley startup Verkada Inc., gaining access to live feeds of 150,000 surveillance cameras inside hospitals, companies, police departments, prisons and schools. Companies whose footage was exposed include carmaker Tesla Inc. and software provider Cloudflare Inc. In addition, hackers were able to view video from inside women's health clinics, psychiatric hospitals and the offices of Verkada itself. Some of the cameras, including in hospitals, use facial-recognition technology to identify and categorize people captured on the footage. The hackers say they also have access to the full video archive of all Verkada customers.
Many healthcare decisions involve navigating through a multitude of treatment options in a sequential and iterative manner to find an optimal treatment pathway with the goal of an optimal patient outcome. Such optimization problems may be amenable to reinforcement learning. A reinforcement learning agent could be trained to provide treatment recommendations for physicians, acting as a decision support tool. However, a number of difficulties arise when using RL beyond benchmark environments, such as specifying the reward function, choosing an appropriate state representation and evaluating the learned policy.