This is Part II of the two-part comprehensive survey devoted to a computing framework most commonly known under the names Hyperdimensional Computing and Vector Symbolic Architectures (HDC/VSA). Both names refer to a family of computational models that use high-dimensional distributed representations and rely on the algebraic properties of their key operations to incorporate the advantages of structured symbolic representations and vector distributed representations. Holographic Reduced Representations is an influential HDC/VSA model that is well-known in the machine learning domain and often used to refer to the whole family. However, for the sake of consistency, we use HDC/VSA to refer to the area. Part I of this survey covered foundational aspects of the area, such as historical context leading to the development of HDC/VSA, key elements of any HDC/VSA model, known HDC/VSA models, and transforming input data of various types into high-dimensional vectors suitable for HDC/VSA. This second part surveys existing applications, the role of HDC/VSA in cognitive computing and architectures, as well as directions for future work. Most of the applications lie within the machine learning/artificial intelligence domain, however we also cover other applications to provide a thorough picture. The survey is written to be useful for both newcomers and practitioners.
The TriRhenaTech alliance presents the accepted papers of the 'Upper-Rhine Artificial Intelligence Symposium' held on October 27th 2021 in Kaiserslautern, Germany. Topics of the conference are applications of Artificial Intellgence in life sciences, intelligent systems, industry 4.0, mobility and others. The TriRhenaTech alliance is a network of universities in the Upper-Rhine Trinational Metropolitan Region comprising of the German universities of applied sciences in Furtwangen, Kaiserslautern, Karlsruhe, Offenburg and Trier, the Baden-Wuerttemberg Cooperative State University Loerrach, the French university network Alsace Tech (comprised of 14 'grandes \'ecoles' in the fields of engineering, architecture and management) and the University of Applied Sciences and Arts Northwestern Switzerland. The alliance's common goal is to reinforce the transfer of knowledge, research, and technology, as well as the cross-border mobility of students.
The ubiquitous availability of computing devices and the widespread use of the internet have generated a large amount of data continuously. Therefore, the amount of available information on any given topic is far beyond humans' processing capacity to properly process, causing what is known as information overload. To efficiently cope with large amounts of information and generate content with significant value to users, we require identifying, merging and summarising information. Data summaries can help gather related information and collect it into a shorter format that enables answering complicated questions, gaining new insight and discovering conceptual boundaries. This thesis focuses on three main challenges to alleviate information overload using novel summarisation techniques. It further intends to facilitate the analysis of documents to support personalised information extraction. This thesis separates the research issues into four areas, covering (i) feature engineering in document summarisation, (ii) traditional static and inflexible summaries, (iii) traditional generic summarisation approaches, and (iv) the need for reference summaries. We propose novel approaches to tackle these challenges, by: i)enabling automatic intelligent feature engineering, ii) enabling flexible and interactive summarisation, iii) utilising intelligent and personalised summarisation approaches. The experimental results prove the efficiency of the proposed approaches compared to other state-of-the-art models. We further propose solutions to the information overload problem in different domains through summarisation, covering network traffic data, health data and business process data.
In the past few decades, artificial intelligence (AI) technology has experienced swift developments, changing everyone's daily life and profoundly altering the course of human society. The intention of developing AI is to benefit humans, by reducing human labor, bringing everyday convenience to human lives, and promoting social good. However, recent research and AI applications show that AI can cause unintentional harm to humans, such as making unreliable decisions in safety-critical scenarios or undermining fairness by inadvertently discriminating against one group. Thus, trustworthy AI has attracted immense attention recently, which requires careful consideration to avoid the adverse effects that AI may bring to humans, so that humans can fully trust and live in harmony with AI technologies. Recent years have witnessed a tremendous amount of research on trustworthy AI. In this survey, we present a comprehensive survey of trustworthy AI from a computational perspective, to help readers understand the latest technologies for achieving trustworthy AI. Trustworthy AI is a large and complex area, involving various dimensions. In this work, we focus on six of the most crucial dimensions in achieving trustworthy AI: (i) Safety & Robustness, (ii) Non-discrimination & Fairness, (iii) Explainability, (iv) Privacy, (v) Accountability & Auditability, and (vi) Environmental Well-Being. For each dimension, we review the recent related technologies according to a taxonomy and summarize their applications in real-world systems. We also discuss the accordant and conflicting interactions among different dimensions and discuss potential aspects for trustworthy AI to investigate in the future.
Most machine learning algorithms are configured by one or several hyperparameters that must be carefully chosen and often considerably impact performance. To avoid a time consuming and unreproducible manual trial-and-error process to find well-performing hyperparameter configurations, various automatic hyperparameter optimization (HPO) methods, e.g., based on resampling error estimation for supervised machine learning, can be employed. After introducing HPO from a general perspective, this paper reviews important HPO methods such as grid or random search, evolutionary algorithms, Bayesian optimization, Hyperband and racing. It gives practical recommendations regarding important choices to be made when conducting HPO, including the HPO algorithms themselves, performance evaluation, how to combine HPO with ML pipelines, runtime improvements, and parallelization.
Zhang, Daniel, Mishra, Saurabh, Brynjolfsson, Erik, Etchemendy, John, Ganguli, Deep, Grosz, Barbara, Lyons, Terah, Manyika, James, Niebles, Juan Carlos, Sellitto, Michael, Shoham, Yoav, Clark, Jack, Perrault, Raymond
Welcome to the fourth edition of the AI Index Report. This year we significantly expanded the amount of data available in the report, worked with a broader set of external organizations to calibrate our data, and deepened our connections with the Stanford Institute for Human-Centered Artificial Intelligence (HAI). The AI Index Report tracks, collates, distills, and visualizes data related to artificial intelligence. Its mission is to provide unbiased, rigorously vetted, and globally sourced data for policymakers, researchers, executives, journalists, and the general public to develop intuitions about the complex field of AI. The report aims to be the most credible and authoritative source for data and insights about AI in the world.
With the development of computer-aided diagnosis (CAD) and image scanning technology, Whole-slide Image (WSI) scanners are widely used in the field of pathological diagnosis. Therefore, WSI analysis has become the key to modern digital pathology. Since 2004, WSI has been used more and more in CAD. Since machine vision methods are usually based on semi-automatic or fully automatic computers, they are highly efficient and labor-saving. The combination of WSI and CAD technologies for segmentation, classification, and detection helps histopathologists obtain more stable and quantitative analysis results, save labor costs and improve diagnosis objectivity. This paper reviews the methods of WSI analysis based on machine learning. Firstly, the development status of WSI and CAD methods are introduced. Secondly, we discuss publicly available WSI datasets and evaluation metrics for segmentation, classification, and detection tasks. Then, the latest development of machine learning in WSI segmentation, classification, and detection are reviewed continuously. Finally, the existing methods are studied, the applicabilities of the analysis methods are analyzed, and the application prospects of the analysis methods in this field are forecasted.
Friedrich, Sarah, Antes, Gerd, Behr, Sigrid, Binder, Harald, Brannath, Werner, Dumpert, Florian, Ickstadt, Katja, Kestler, Hans, Lederer, Johannes, Leitgöb, Heinz, Pauly, Markus, Steland, Ansgar, Wilhelm, Adalbert, Friede, Tim
The research on and application of artificial intelligence (AI) has triggered a comprehensive scientific, economic, social and political discussion. Here we argue that statistics, as an interdisciplinary scientific field, plays a substantial role both for the theoretical and practical understanding of AI and for its future development. Statistics might even be considered a core element of AI. With its specialist knowledge of data evaluation, starting with the precise formulation of the research question and passing through a study design stage on to analysis and interpretation of the results, statistics is a natural partner for other disciplines in teaching, research and practice. This paper aims at contributing to the current discussion by highlighting the relevance of statistical methodology in the context of AI development. In particular, we discuss contributions of statistics to the field of artificial intelligence concerning methodological development, planning and design of studies, assessment of data quality and data collection, differentiation of causality and associations and assessment of uncertainty in results. Moreover, the paper also deals with the equally necessary and meaningful extension of curricula in schools and universities.
Objective: This work investigates the hypothesis that focal seizures can be predicted using scalp electroencephalogram (EEG) data. Our first aim is to learn features that distinguish between the interictal and preictal regions. The second aim is to define a prediction horizon in which the prediction is as accurate and as early as possible, clearly two competing objectives. Methods: Convolutional filters on the wavelet transformation of the EEG signal are used to define and learn quantitative signatures for each period: interictal, preictal, and ictal. The optimal seizure prediction horizon is also learned from the data as opposed to making an a priori assumption. Results: Computational solutions to the optimization problem indicate a ten-minute seizure prediction horizon. This result is verified by measuring Kullback-Leibler divergence on the distributions of the automatically extracted features. Conclusion: The results on the EEG database of 204 recordings demonstrate that (i) the preictal phase transition occurs approximately ten minutes before seizure onset, and (ii) the prediction results on the test set are promising, with a sensitivity of 87.8% and a low false prediction rate of 0.142 FP/h. Our results significantly outperform a random predictor and other seizure prediction algorithms. Significance: We demonstrate that a robust set of features can be learned from scalp EEG that characterize the preictal state of focal seizures.
The use of multiple drugs, termed polypharmacy, is common to treat patients with complex diseases or co-existing medical conditions. However, a major consequence of polypharmacy is a much higher risk of side effects for the patient. Polypharmacy side effects emerge because of drug interactions, in which activity of one drug may change, favorably or unfavorably, if taken with another drug. The knowledge of drug interactions is limited because these complex relationships are usually not observed in small clinical testing. Discovering polypharmacy side effects thus remains a challenge with significant implications for patient mortality and morbidity. Here we introduce Decagon, an approach for modeling polypharmacy side effects. The approach constructs a multimodal graph of protein-protein interactions, drug-protein interactions, and the polypharmacy side effects, which are represented as drug-drug interactions, where each side effect is an edge of a different type. Decagon is developed specifically to handle such multimodal graphs with a large number of edge types. Our approach develops a new graph convolutional neural network for multirelational link prediction in multimodal networks. Unlike approaches limited to predicting simple drug-drug interaction values, Decagon can predict the exact side effect, if any, through which a given drug combination manifests clinically. Decagon accurately predicts polypharmacy side effects, outperforming baselines by up to 69%. Furthermore, Decagon models particularly well side effects that have a strong molecular basis, while on predominantly non-molecular side effects, it achieves good performance because of effective sharing of model parameters across edge types. Decagon creates an opportunity to use large molecular and patient population data to flag and prioritize polypharmacy side effects for follow-up analysis via formal pharmacological studies.