Commodity Chemicals


Artificial Intelligence: BASF partner with Nuritas on 'next gen' functional peptides

#artificialintelligence

The first step of the partnership will see Nuritas, a biotech and R&D start-up that uses artificial intelligence and new technologies for the discovery of novel food and health ingredients, grant an exclusive royalty-based license to BASF to commercialise one of its existing peptides. A second part of the deal will focus on the discovery of new functional peptides, based on health areas that are strategically important to BASF, using Nuritas' technological expertise and AI platform. According to BASF, peptide networks of focus in the collaboration will be natural, food-derived, patented and of significant benefit to health – including peptides that bring about anti-inflammatory responses. "Cooperating with an innovative and agile start-up like Nuritas enables us to further expand our already broad portfolio of health solutions," commented Saori Dubourg, head of BASF's Nutrition & Health Business. Nuritas' unique platform combines DNA analysis and artificial intelligence (AI) to predict, unlock, and validate peptides from natural sources.


Applying the Subdue Substructure Discovery System to the Chemical Toxicity Domain

AAAI Conferences

The ever-increasing number of chemical compounds added every year has not been accompanied by a similar growth in our ability to analyze and classify these compounds. The problem of prevention of cancer caused by many of these chemicals has been of great scientific and humanitarian value. The use of AI discovery tools for predicting chemical toxicity is being investigated. The basic idea behind the work is to obtain structure-activity representation (SARs)[Srinivasan et al.], which relates molecular structures to cancerous activity. The data is obtained from the U.S National Toxicology Program conducted by the National Institute of Environmental Health Sciences (NIEHS). A general approach to automatically discover repetitive substructures from the datasets is outlined by this research. Relevant SARs are identified using the Subdue substructure discovery system that discovers commonly occurring substructures in a given set of compounds. The best substructure given by Subdue is used as a pattern indicative of cancerous activity.


SS95-03-001.pdf

AAAI Conferences

What is a Systematic Method of Scientific Discovery? Herbert A. Simon Department of Psychology Carnegie Mellon University Pittsburgh, PA 15213 Creativity in general, and scientific discovery as a particular form of creativity, has always been surrounded by an aura of mysticism. We continue to recount the mystical experiences of Kekule with his benzene ring, or Poincare stepping on the bus at Caen, or Archimedes running naked from his bath, shouting "Eureka!". Attempts to explain discovery in terms of normal thought processes are regretted or even resented as assaults on the mystery. Nevertheless, there is mounting evidence that scientific discovery is explicable - that there is method in the madness of the moment of inspiration or illumination.