We present a practical health-theme machine learning (ML) application concerning `AI for social good' domain for `Producing Good Outcomes' track. In particular, the solution is concerning the problem of a potential elderly adult dementia onset prediction in aging societies. The paper discusses our attempt and encouraging preliminary study results of behavioral responses analysis in a working memory-based emotional evaluation experiment. We focus on the development of digital biomarkers for dementia progress detection and monitoring. We present a behavioral data collection concept for a subsequent AI-based application together with a range of regression encouraging results of Montreal Cognitive Assessment (MoCA) scores in the leave-one-subject-out cross-validation setup. The regressor input variables include experimental subject's emotional valence and arousal recognition responses, as well as reaction times, together with self-reported education levels and ages, obtained from a group of twenty older adults taking part in the reported data collection project. The presented results showcase the potential social benefits of artificial intelligence application for elderly and establish a step forward to develop ML approaches, for the subsequent application of simple behavioral objective testing for dementia onset diagnostics replacing subjective MoCA.
In modern data science, dynamic tensor data is prevailing in numerous applications. An important task is to characterize the relationship between such dynamic tensor and external covariates. However, the tensor data is often only partially observed, rendering many existing methods inapplicable. In this article, we develop a regression model with partially observed dynamic tensor as the response and external covariates as the predictor. We introduce the low-rank, sparsity and fusion structures on the regression coefficient tensor, and consider a loss function projected over the observed entries. We develop an efficient non-convex alternating updating algorithm, and derive the finite-sample error bound of the actual estimator from each step of our optimization algorithm. Unobserved entries in tensor response have imposed serious challenges. As a result, our proposal differs considerably in terms of estimation algorithm, regularity conditions, as well as theoretical properties, compared to the existing tensor completion or tensor response regression solutions. We illustrate the efficacy of our proposed method using simulations, and two real applications, a neuroimaging dementia study and a digital advertising study.
Recently, researchers have started applying convolutional neural networks (CNNs) with one-dimensional convolutions to clinical tasks involving time-series data. This is due, in part, to their computational efficiency, relative to recurrent neural networks and their ability to efficiently exploit certain temporal invariances, (e.g., phase invariance). However, it is well-established that clinical data may exhibit many other types of invariances (e.g., scaling). While preprocessing techniques, (e.g., dynamic time warping) may successfully transform and align inputs, their use often requires one to identify the types of invariances in advance. In contrast, we propose the use of Sequence Transformer Networks, an end-to-end trainable architecture that learns to identify and account for invariances in clinical time-series data. Applied to the task of predicting in-hospital mortality, our proposed approach achieves an improvement in the area under the receiver operating characteristic curve (AUROC) relative to a baseline CNN (AUROC=0.851 vs. AUROC=0.838). Our results suggest that a variety of valuable invariances can be learned directly from the data.
Epilepsy occurs when localized electrical activity of neurons suffer from an imbalance. One of the most adequate methods for diagnosing and monitoring is via the analysis of electroencephalographic (EEG) signals. Despite there is a wide range of alternatives to characterize and classify EEG signals for epilepsy analysis purposes, many key aspects related to accuracy and physiological interpretation are still considered as open issues. In this paper, this work performs an exploratory study in order to identify the most adequate frequently-used methods for characterizing and classifying epileptic seizures. In this regard, a comparative study is carried out on several subsets of features using four representative classifiers: Linear Discriminant Analysis (LDA), Quadratic Discriminant Analysis (QDA), K-Nearest Neighbor (KNN), and Support Vector Machine (SVM).
In this paper we introduce a new feature selection algorithm to remove the irrelevant or redundant features in the data sets. In this algorithm the importance of a feature is based on its fitting to the Catastrophe model. Akaike information crite- rion value is used for ranking the features in the data set. The proposed algorithm is compared with well-known RELIEF feature selection algorithm. Breast Cancer, Parkinson Telemonitoring data and Slice locality data sets are used to evaluate the model.