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Oxford Nanopore's Hand-Held DNA Analyzer Has Traveled the World

MIT Technology Review

Last June, a British-Brazilian scientific team boarded a bus that had been turned into a makeshift laboratory and headed out to tour six cities across northeastern Brazil. The researchers were there to find mosquitoes infected with the Zika virus and sequence its genome in their blood, since the evolution of the viral genome contains clues to the epidemic's origins. But rather than collect insects and send the samples back to a central lab, they'd outfitted the bus with everything they needed to do the research.


The genomics intelligence revolution

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Mahni Ghorashi is the co-founder of Clear Labs, where he leads commercial activities including strategy, marketing and business development. Gaurav Garg is a founding partner of Wing Venture Capital. We've entered a new phase in the history of whole genome sequencing (WGS). Consider that researchers at University of Toronto just launched a massive project to sequence the whole genomes of 10,000 people per year. This is truly astounding when you recall that it took 13 years and $3 billion to sequence the first human genome, and that as recently as 2012 there were only 69 whole human genomes that had ever been sequenced.


'We are at the beginning of a revolution in healthcare'

BBC News

Fifteen years ago this month, the full human genome sequence was published for the first time, heralding a new era of medicine. Since then technology has markedly speeded up genomic sequencing and reduced the cost. But have those hoped-for medical breakthroughs materialised? "We have embarked on one of the most exciting chapters of the book of life," said Prof Allan Bradley, director of the Wellcome Trust Sanger Institute, as he welcomed the success of the Human Genome Project. Sequencing the human genome took 10 years and cost about $30bn (£21.5bn).


Industry News

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Find here a listing of the latest industry news in genomics, genetics, precision medicine, and beyond. Updates are provided on a monthly basis. Sign-Up for our newsletter and never miss out on the latest news and updates. As 2019 came to an end, Veritas Genetics struggled to get funding due to concerns it had previously taken money from China. It was forced to cease US operations and is in talks with potential buyers. The GenomeAsia 100K Project announced its pilot phase with hopes to tackle the underrepresentation of non-Europeans in human genetic studies and enable genetic discoveries across Asia. Veritas Genetics, the start-up that can sequence a human genome for less than $600, ceases US operations and is in talks with potential buyers Veritas Genetics ceases US operations but will continue Veritas Europe and Latin America. It had trouble raising funding due to previous China investments and is looking to be acquired. Illumina loses DNA sequencing patents The European Patent ...


Metagenomic sequencing at the epicenter of the Nigeria 2018 Lassa fever outbreak

Science

Lassa fever is a hemorrhagic viral disease endemic to West Africa. Usually, each year sees only a smattering of cases reported, but hospitalized patients risk a 15% chance of death. Responding to fears that a 10-fold surge in cases in Nigeria in 2018 signaled an incipient outbreak, Kafetzopoulou et al. performed metagenomic nanopore sequencing directly from samples from 120 patients (see the Perspective by Bhadelia). Results showed no strong evidence of a new strain emerging nor of person-to-person transmission; rather, rodent contamination was the main source. To prevent future escalation of this disease, we need to understand what triggers the irruption of rodents into human dwellings.