Collaborating Authors

Researchers Enhance Alzheimer's Disease Classification through Artificial Intelligence


For media inquiries, please contact Gina DiGravio: 617-224-8962, Warning signs for Alzheimer's disease (AD) can begin in the brain years before the first symptoms appear. Spotting these clues may allow for lifestyle changes that could possibly delay the disease's destruction of the brain. "Improving the diagnostic accuracy of Alzheimer's disease is an important clinical goal. If we are able to increase the diagnostic accuracy of the models in ways that can leverage existing data such as MRI scans, then that can be hugely beneficial," explained corresponding author Vijaya B. Kolachalama, PhD, assistant professor of medicine at Boston University School of Medicine (BUSM).

Another reason to keep your blood pressure down: It can lower your risk of dementia

Los Angeles Times

The new findings emerge from a clinical trial called SPRINT (short for Systolic Blood Pressure Intervention Trial), which began in 2010 and ran for less than five years. After trial subjects had been followed for an average of just over three years, the trial was shut down because the trial's findings showed so strongly the benefits of the lower systolic blood pressure goal in protecting people's hearts. In August 2015, a board of safety monitors said it no longer could justify maintaining some of the trial's subjects at the systolic target level of 140 mmHG.

Clever math enables MRI to map biomolecules


MRI scanners can map a person's innards in exquisite detail, but they say little about composition. Now, physicists are pushing MRI to a new realm of sensitivity to trace specific biomolecules in tissues, a capability that could aid in diagnosing Alzheimer's and other diseases. The advance springs not from improved scanners, but from better methods to solve a notoriously difficult math problem and extract information already latent in MRI data. Researchers are already using the new techniques to trace a fatty molecule called myelin in the brains of people with multiple sclerosis, mild cognitive impairment, and Alzheimer's disease. They also show that the scans can trace a molecule called proteoglycan in knee cartilage.

New blood test detects Alzheimer's on par with expensive diagnostic tools, study finds

FOX News

Fox News Flash top headlines are here. Check out what's clicking on A new blood test was able to spot Alzheimer's disease on par with pricey brain imaging and spinal taps, researchers found. The team, which included researchers from Sweden, published their findings on Tuesday in JAMA. The test may offer a cheaper route for Alzheimer's diagnostic testing, though it could take years to validate as a reliable option, USA TODAY reported.

Scientists develop an eye scanner that can detect and track biological ageing in humans

Daily Mail - Science & tech

A'game-changing' eye scanner that can detect someone's biological age by examining the lens of their eye, has been developed by scientists. There is no universally accepted measure of biological ageing, according to the Boston University School of Medicine team, who built the scanner. The new, non-invasive technology, will allow researchers to find out someone's'true' or biological age, rather than how long they have been alive. According to the researchers, chronological age - how long you've been alive - does not adequately measure the rate someones body is actually ageing. They say that by knowing someone's biological age, and being able to track it throughout their life, can help in improving medical care.