For centuries, scientists who have dedicated their lives to studying the human brain have attempted to unlock its mysteries. The role the brain plays in human personality -- as well as the myriad of disorders and conditions that come along with it -- is often difficult to study because studying the organ while it's still functioning in a human body is complicated. Now, researchers at The Allen Institute for Brain Science have introduced a new tool that could make such study a whole lot easier: functioning virtual brain cells. The fully 3D computer models of living human brain tissue are based on actual brain samples that were left over after surgery, and present what could be the most powerful testbed for studying the human brain ever created. The samples used to construct the virtual models was healthy tissue that was removed during brain operations, and represents parts of the brain that are typically associated with thoughts and consciousness, as well as memory.
In the past two million years, humans have experienced a massive increase in brain size, one not seen in any other species. This rapid evolution gave us brains roughly triple the volume of those of our pre-human ancestors. But the intelligence we enjoy as a result would seem to be advantageous for all sorts of species, not just us. So why was ours the only line to go down this route? The social brain hypothesis was a popular answer.
It turns out that in larger human brains, regions involved in bringing together information are hyperexpanded – but we don't know what affect this might have on intelligence yet. Armin Raznahan at the US National Institute of Mental Health in Maryland and his colleagues discovered this by comparing brain images from around 3,000 people. They compared the area of 80,000 points across the cortex – the large part of our brains that is involved in higher functions like thinking. Analysing these, they found that some particular areas expanded more than others in people who had an overall larger brain size. These regions seem to be involved in integrating information from across the brain, he says.
Just one in 10 babies exposed to the Zika virus during pregnancy get the brain damage that causes microcephaly – abnormally small heads. Now there's a first clue about what stops this from happening in the rest – their gene activity. Blood samples were taken from three pairs of non-identical twins in Brazil. In each of these pairs, one baby had brain damage and the other didn't. Stem cells were then made from their blood cells, and matured into brain cells, allowing researchers to see how the brain cells …