Great white sharks may hold the secrets to curing cancer and other age-related diseases, experts believe. The first map of great whites sharks' DNA has revealed "mutations" that protect the animals against cancer and other illnesses. Scientists hope more research could help apply the findings to treating age-related illnesses in humans. Great whites also have the ability to repair their own DNA - something we can't do. The research was carried out by a team of scientists at the Save Our Seas Foundation Shark Research Centre at Nova Southeastern University in Florida.
How long can a human live? Researchers have finally put a number to the key problem that has baffled scientists and spiritualists alike. The answer may not be very encouraging to those rooting for immortality. A technology-enabled study on the correlation between aging and the loss of the ability to recover from stresses identified 150 years to be the upper limit of human longevity. The study, published on Tuesday in the Nature Communications journal, was conducted by researchers from Roswell Park Comprehensive Cancer Center in Buffalo, NY, and Gero, a Singapore-based biotech company.
We're continuing to release talks from Ending Age-Related Diseases 2019, our highly successful two-day conference that featured talks from leading researchers and investors, bringing them together to discuss the future of aging and rejuvenation biotechnology. Dr. Qingsong Zhu, the COO of Insilico Medicine, discussed the use of deep learning in creating biomarkers for aging. Initially discussing existing clocks and the problems with animal translation, he went on to discuss what sorts of markers are ideal for age-related research and the details of training and testing a model that works with these markers, showing that a deep model compares favorably to other models. He also used his model to show that smoking does, in fact, cause accelerated aging.
A patch implanted at the back of the eye has improved or stabilised sight in four people with severe age-related macular degeneration. The treatment enabled one 69-year-old woman to read 24 letters on a standard eye chart, when she could previously manage only seven. The patch is made of eye cells made from human embryonic stem cells, and it has been designed for treating the "dry" form of macular degeneration, which accounts for 90 per cent of all cases, and affects 1.7 million people in the US. Similar patches and treatments have already been tested against the "wet" form – in which blood vessels invade and destroy the retinal pigment epithelial cells that nourish and support the photoreceptor cells that capture light. The "dry" form is caused by natural deposits on the retina that gradually kill retinal pigment epithelial cells.
There are several scientists that are now convinced upon the idea that while aging is a natural occurrence that happens in all creatures, it is, in fact, a disease that can be treated or cured. In that regards, there are some scientists out there looking to slow down the process of aging, while others are looking to stop it all together. Some of these ideas have been spurred on by the development of certain technologies, such as combining stem cells with genetic and cellular manipulation. Researchers have also been looking into the rejuvenating effects of proteins that are found in human blood, while others suggest using bacteria to ward off old age. Alex Zhavoronkov is director of both the International Aging Research Portfolio (IARP) and the Biogerontology Research Foundation and the CEO of bioinformatics company, Insilico Medicine and he has a different idea altogether.