Herpes viruses in the brain linked to Alzheimer's disease

New Scientist

The most in-depth analysis of human brain tissue ever done in Alzheimer's disease has found evidence for the controversial theory that viruses play a role in the condition. If true, it could mean that some instances of Alzheimer's might be treated with anti-viral drugs. Alzheimer's is the most common cause of dementia, affecting some 47 million people worldwide.


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Out of the total number, 48 were scans of people with the disease, while 48 were scans of people who suffered from mild cognitive impairment and eventually developed full-blown Alzheimer's. The AI was able to diagnose Alzheimer's 86 percent of the time. More importantly, it was able to detect mild cognitive impairment 84 percent of the time, making it a potentially effective tool for early diagnosis. With more samples and further development, though, the AI could become more accurate until it's reliable enough to be used as a non-invasive early detection system.


5 Siblings Worry About Developing Alzheimer's Like Parents

U.S. News

Her grandmother is neither the first nor the last in this Colorado family to suffer from the degenerative brain disorder. Five family members across at least two generations of the family have had Alzheimer's disease. And a sixth family member, Nelson's great-grandmother, was diagnosed with what was called "forgetfulness" before her death in 1976.


[Perspective] Quantifying protein (dis)order

Science

Twenty-five years ago, Chothia predicted that the structural domains of all proteins can be classified into about 1000 folds (1). Later studies refined this number; however, scientists also found that some proteins or parts of proteins never assume a specific fold. These regions are called intrinsically unstructured or disordered (2). Oncogenes such as p53 or breast cancer 1 (BRCA1) contain long disordered stretches, and aggregation of the disordered α-synuclein is thought to underlie Parkinson's and Alzheimer's diseases (3, 4).


Alzheimer's Or NPH: Both Can Steal Your Identity, But You Can Come Back From One

Forbes Technology

There are some things one can only achieve by a deliberate leap in the opposite direction. The first time it happened was in 1999. I was fast asleep when the phone next to my bed rang. Mom said one side of dad's face was drooping and he was confused. My dad didn't get confused.