The most in-depth analysis of human brain tissue ever done in Alzheimer's disease has found evidence for the controversial theory that viruses play a role in the condition. If true, it could mean that some instances of Alzheimer's might be treated with anti-viral drugs. Alzheimer's is the most common cause of dementia, affecting some 47 million people worldwide.
Out of the total number, 48 were scans of people with the disease, while 48 were scans of people who suffered from mild cognitive impairment and eventually developed full-blown Alzheimer's. The AI was able to diagnose Alzheimer's 86 percent of the time. More importantly, it was able to detect mild cognitive impairment 84 percent of the time, making it a potentially effective tool for early diagnosis. With more samples and further development, though, the AI could become more accurate until it's reliable enough to be used as a non-invasive early detection system.
Twenty-five years ago, Chothia predicted that the structural domains of all proteins can be classified into about 1000 folds (1). Later studies refined this number; however, scientists also found that some proteins or parts of proteins never assume a specific fold. These regions are called intrinsically unstructured or disordered (2). Oncogenes such as p53 or breast cancer 1 (BRCA1) contain long disordered stretches, and aggregation of the disordered α-synuclein is thought to underlie Parkinson's and Alzheimer's diseases (3, 4).
In science news around the world, the coral die-off in 2016 in the Great Barrier Reef because of bleaching reaches a new record, results of the 2015 Trends in International Mathematics and Science Study show that East Asian students still lead the world in math and science scores, a widely watched candidate drug for Alzheimer's disease fails, a cancer immunotherapy trial claims two more lives on top of three earlier this year, and more. Also, U.S. President-elect Donald Trump names his nominees to head the Department of Health and Human Services and the Department of Education. And ant "kisses" can transfer not only nutrients, but also hormones that help shape their colonies' long-term fate.