Kyoto University performs world's first iPS cell transplant for Parkinson's

The Japan Times

KYOTO – Kyoto University said Friday it has conducted the world's first transplant of induced pluripotent stem cells to treat Parkinson's disease. Nerve cells created from the artificially derived stem cells, known as iPS cells, were transplanted into the brain of a patient in his 50s in October in a treatment researchers hope to develop into a method that can be covered under Japan's health insurance system. "By also cooperating with companies, we want to develop a mass production system that enables us to deliver nerve cells derived from iPS cells to all over the world," said Jun Takahashi, a professor at the university's Center for iPS Cell Research and Application who led the research team, at a news conference. Parkinson's disease reduces dopamine-producing neurons in the brain and results in tremors in the hands and feet and stiffness in the body. While there are treatments to relieve the symptoms, there is currently no cure for the disease.


Sam Shepard, Pulitzer Prize-winning playwright and keen observer of American family life, dies at 73

PBS NewsHour

Actor Sam Shepard, seen here during the Winter 2014 TCA presentations in Pasadena, California, died last week at the age of 73. Pulitzer Prize-winning playwright and Oscar-nominated actor Sam Shepard died in Kentucky last week following a battle with ALS, also known as Lou Gehrig's disease, a spokesperson for the family told news outlets. He was 73 years old. Shepard's acclaimed plays, known for their surrealist elements, dark humor and keen observations of the American family, include "True West," "Fool for Love" and "Buried Child," which won the Pulitzer Prize for drama. Shepard was also nominated for an Academy Award for his role as Chuck Yeager in the 1983 film "The Right Stuff," the story of the astronauts who made the first manned spaceflight by the United States.


Sam Shepard, Pulitzer Prize-winning playwright and Oscar-nominated actor, dies at 73

Los Angeles Times

A giant in the arts, Sam Shepard, the Oscar-nominated actor, Pulitzer Prize-winning playwright, author, screenwriter and director, died Thursday at his home in Kentucky of complications from ALS (or Lou Gehrig's disease). Chris Boneau, a spokesman for Shepard's family, confirmed Shepard's death to The Times in a statement. "The family requests privacy at this difficult time," he said. Shepard received the Pulitzer Prize for drama in 1979 for his play "Buried Child," which centers around a family haunted by the past as it comes together in its aging Illinois farmhouse, reflecting shades of Shepard's own childhood in the state with his alcoholic father. Five years later, Shepard was acknowledged by the Academy of Motion Picture Arts and Sciences when he was nominated for best supporting actor for his portrayal of Chuck Yeager in "The Right Stuff."


Sam Shepard dead at 73

FOX News

Pulitzer Prize-winning playwright and actor Sam Shepard, died at his Kentucky home Thursday, Fox News learned Monday. A family spokesperson told us the Oscar-nominated actor and celebrated author whose plays chronicled the explosive fault lines of family and masculinity in the American West, died from complications related to Lou Gehrig's disease, or amyotrophic lateral sclerosis. The taciturn Shepard, who grew up on a California ranch, was a man of few words who nevertheless produced 44 plays and numerous books, memoirs and short stories. He was one of the most influential playwrights of his generation: a plain-spoken poet of the modern frontier who combined ruggedness with lyricism. In his 1971 one-act "Cowboy Mouth, which he wrote with his then girlfriend, musician and poet Patti Smith, one character says, "People want a street angel.


Sam Shepard, playwright and star of 'Bloodline' and 'The Right Stuff,' dead at 73

Mashable

Sam Shepard, Pulitzer-winning playwright and Oscar-nominated actor who played legendary test pilot Chuck Yeager in The Right Stuff and the Rayburn family patriarch in the Netflix drama series Bloodline, has died. Shepard died Thursday at his Kentucky home of complications from Lou Gehrig's disease, a family spokesman confirmed Monday morning. Shepard was nominated for three Pulitzers, winning for the 1979 drama Buried Child. His plays explored the dark underside of American family life, portraying marriages, sibling rivalries and other family dynamics struggling to survive the fragile American dream. His other Pulitzer nominations came for the Broadway productions True West and Fool for Love.