STOCKHOLM – Japanese scientist Tasuku Honjo was awarded on Monday this year's Nobel Prize in physiology or medicine, for his discovery of a protein that contributed to the development of an immunotherapeutic drug against cancer. Honjo, a 76-year-old professor at Kyoto University, won the prize with U.S. national James Allison, the Nobel Assembly at the Karolinska Institute said. Honjo opened a pathway for a new cancer treatment by discovering the PD-1 protein, which is responsible for suppressing immune response. "I'm very honored and pleased to receive the Nobel Prize in physiology or medicine," Honjo told a news conference following the announcement. His method of treating cancer -- by controlling the protein's function to suppress immunity -- led to the development of Nivolumab, a drug marketed as Opdivo and used against lung cancer and melanoma.
Two immunologists, James Allison from the University of Texas Austin and Tasuku Honjo from Kyoto University, have won the 2018 Nobel Medicine Prize for research that has revolutionised the treatment of cancer. The pair were honoured'for their discovery of cancer therapy by inhibition of negative immune regulation,' the Nobel Assembly said. Immune checkpoint inhibitor therapy targets proteins made by some immune system cells, as well as some cancer cells. The proteins can stop the body's natural defences from killing cancer cells. The therapy is designed to remove this protein'brake' and allow the immune system to more quickly get to work fighting the cancer.
James Allison of the University of Texas and Tasuku Honjo of Kyoto University will share the 9-million-kronor ($1.01 million) prize for 2018. Researchers from the United States and Japan won the Nobel Prize in medicine on Monday for discoveries that help the body marshal its cellular troops to attack invading cancers. One cancer doctor said "an untold number of lives ... have been saved by the science that they pioneered." James Allison of the University of Texas and Tasuku Honjo of Kyoto University will share the 9-million-kronor ($1.01 million) prize for 2018. Their parallel work concerned proteins that act as brakes on the body's immune system.
While there are now scientific awards with larger monetary prizes, there is no prize so universally and immediately recognized as a sign of prestige. The 2018 season kicked off on Monday with the Nobel Prize in Physiology or Medicine, which this year honors two researchers for their work on cancer therapy. James P. Allison, 70, born in Alice, Texas, and now affiliated with the University of Texas MD Anderson Cancer Center and the Parker Institute for Cancer Immunotherapy in San Francisco, splits the prize with Tasuku Honjo, 76, a professor at Kyoto University in Japan. Their joint prize includes 9,000,000 Swedish Krona, which is a bit more than $1,000,000 USD. In the 1990s, Allison and Honjo did separate but parallel research on the use of the human immune system to fight cancer.
Two scientists who discovered how to fight cancer using the body's immune system have won the 2018 Nobel Prize for physiology or medicine. The work by James P Allison, from the US, and Tasuku Honjo, from Japan, has led to treatments for advanced, deadly skin cancer. Immune checkpoint therapy has revolutionised cancer treatment, said the prize-giving Swedish Academy. Experts say it has proved to be "strikingly effective". Allison, a professor at the University of Texas, and Honjo, a professor at Kyoto University, will share the Nobel prize sum of nine million Swedish kronor - about $1.01 million or 870,000 euros.