IBM's AI blood test could help with early Alzheimer's detection

Engadget

Previous attempts to find a cure for Alzheimer's ended up in failure, but a new study out of IBM Research has the potential to spark a major breakthrough. A group of IBM researchers have harnessed the powers of machine learning to figure out a way to detect a biological marker associated with the disease -- a peptide called amyloid-beta -- with a simple blood test. The solution they came up with can even detect an individual's risk for Alzheimer's earlier than a brain scan can and way before symptoms start showing up. It can arm doctors with the ammo they need to be able to take better care of their patients. According to a study published in 2017, the concentration of amyloid-beta in a person's spinal fluid starts changing decades before the first signs of the disease show up.


IBM takes on Alzheimer's disease with machine learning

ZDNet

IBM has introduced machine learning (ML) to the diagnostics field in the hopes that one day these technologies may assist in the creation of stable and effective diagnostic tests for early-onset Alzheimer's. On Monday, the tech giant said ML and artificial intelligence (AI) can be exploited to replace invasive and expensive tests for the disease. A paper documenting the research, conducted by IBM's Australian team, has been published in Scientific Reports. Alzheimer's is currently incurable and can only be treated by palliative means. Symptoms for the disease include the gradual degradation of memory, confusion, and difficulty in completing once-familiar daily tasks.


IBM takes on Alzheimer's disease with machine learning

#artificialintelligence

IBM has introduced machine learning (ML) to the diagnostics field in the hopes that one day these technologies may assist in the creation of stable and effective diagnostic tests for early-onset Alzheimer's. On Monday, the tech giant said ML and artificial intelligence (AI) can be exploited to replace invasive and expensive tests for the disease. A paper documenting the research, conducted by IBM's Australian team, has been published in Scientific Reports. Alzheimer's is currently incurable and can only be treated by palliative means. Symptoms for the disease include the gradual degradation of memory, confusion, and difficulty in completing once-familiar daily tasks.


Alzheimer's could be detected in middle age before symptoms appear

Daily Mail - Science & tech

A revolutionary blood test could predict 20 years in advance if a person will develop Alzheimer's disease. Scientists hope the breakthrough could prevent victims having to reach an advanced stage before they are diagnosed. It may also help middle-aged people determine their risk of the devastating condition. The German researchers claim their test can identify the proteins involved with the disease as they seep into the blood stream. Known as amyloid-beta peptides, these misshapen strings clump together in the brains of people with Alzheimer's, slowly killing off the surrounding cells.


how-alzheimers-disease-risk-connected-poor-sleep-quality-2564586

International Business Times

Having disrupted sleep leads to increase in brain proteins associated with Alzheimer's disease, results of a study showed Monday. "We were not surprised to find that tau levels didn't budge after just one night of disrupted sleep while amyloid levels did, because amyloid levels normally change more quickly than tau levels," Yo-El Ju, assistant professor of neurology and the lead study author, said in a statement. "I think that may lead to chronically elevated amyloid levels, which animal studies have shown lead to increased risk of amyloid plaques and Alzheimer's." "As Alzheimer's disease progresses, caregiving becomes very important," Christopher Taylor, a CDC epidemiologist who led the study team, told the news outlet at the time.