Gaussian-binary Restricted Boltzmann Machines on Modeling Natural Image Statistics Machine Learning

We present a theoretical analysis of Gaussian-binary restricted Boltzmann machines (GRBMs) from the perspective of density models. The key aspect of this analysis is to show that GRBMs can be formulated as a constrained mixture of Gaussians, which gives a much better insight into the model's capabilities and limitations. We show that GRBMs are capable of learning meaningful features both in a two-dimensional blind source separation task and in modeling natural images. Further, we show that reported difficulties in training GRBMs are due to the failure of the training algorithm rather than the model itself. Based on our analysis we are able to propose several training recipes, which allowed successful and fast training in our experiments. Finally, we discuss the relationship of GRBMs to several modifications that have been proposed to improve the model.

A General Framework for Uncertainty Estimation in Deep Learning Machine Learning

End-to-end learning has recently emerged as a promising technique to tackle the problem of autonomous driving. Existing works show that learning a navigation policy from raw sensor data may reduce the system's reliance on external sensing systems, (e.g. GPS), and/or outperform traditional methods based on state estimation and planning. However, existing end-to-end methods generally trade off performance for safety, hindering their diffusion to real-life applications. For example, when confronted with an input which is radically different from the training data, end-to-end autonomous driving systems are likely to fail, compromising the safety of the vehicle. To detect such failure cases, this work proposes a general framework for uncertainty estimation which enables a policy trained end-to-end to predict not only action commands, but also a confidence about its own predictions. In contrast to previous works, our framework can be applied to any existing neural network and task, without the need to change the network's architecture or loss, or to train the network. In order to do so, we generate confidence levels by forward propagation of input and model uncertainties using Bayesian inference. We test our framework on the task of steering angle regression for an autonomous car, and compare our approach to existing methods with both qualitative and quantitative results on a real dataset. Finally, we show an interesting by-product of our framework: robustness against adversarial attacks.

Neural Networks for Determining Protein Specificity and Multiple Alignment of Binding Sites

AAAI Conferences

Regulation of gene expression often involves proteins that bind to particular regions of DNA. Determining the binding sites for a protein and its specificity usually requires extensive biochemical and/or genetic experimentation. In this paper we illustrate the use of a neural network to obtain the desired information with much less experimental effort. It is often fairly easy to obtain a set of moderate length sequences, perhaps one or two hundred base-pairs, that each contain binding sites for the protein being studied. For example, the upstream regions of a set of genes that are all regulated by the same protein should each contain binding sites for that protein.

Deep Bayesian Multi-Target Learning for Recommender Systems Machine Learning

With the increasing variety of services that e-commerce platforms provide, criteria for evaluating their success become also increasingly multi-targeting. This work introduces a multi-target optimization framework with Bayesian modeling of the target events, called Deep Bayesian Multi-Target Learning (DBMTL). In this framework, target events are modeled as forming a Bayesian network, in which directed links are parameterized by hidden layers, and learned from training samples. The structure of Bayesian network is determined by model selection. We applied the framework to Taobao live-streaming recommendation, to simultaneously optimize (and strike a balance) on targets including click-through rate, user stay time in live room, purchasing behaviors and interactions. Significant improvement has been observed for the proposed method over other MTL frameworks and the non-MTL model. Our practice shows that with an integrated causality structure, we can effectively make the learning of a target benefit from other targets, creating significant synergy effects that improve all targets. The neural network construction guided by DBMTL fits in with the general probabilistic model connecting features and multiple targets, taking weaker assumption than the other methods discussed in this paper. This theoretical generality brings about practical generalization power over various targets distributions, including sparse targets and continuous-value ones.

Self-Adversarially Learned Bayesian Sampling Machine Learning

Scalable Bayesian sampling is playing an important role in modern machine learning, especially in the fast-developed unsupervised-(deep)-learning models. While tremendous progresses have been achieved via scalable Bayesian sampling such as stochastic gradient MCMC (SG-MCMC) and Stein variational gradient descent (SVGD), the generated samples are typically highly correlated. Moreover, their sample-generation processes are often criticized to be inefficient. In this paper, we propose a novel self-adversarial learning framework that automatically learns a conditional generator to mimic the behavior of a Markov kernel (transition kernel). High-quality samples can be efficiently generated by direct forward passes though a learned generator. Most importantly, the learning process adopts a self-learning paradigm, requiring no information on existing Markov kernels, e.g., knowledge of how to draw samples from them. Specifically, our framework learns to use current samples, either from the generator or pre-provided training data, to update the generator such that the generated samples progressively approach a target distribution, thus it is called self-learning. Experiments on both synthetic and real datasets verify advantages of our framework, outperforming related methods in terms of both sampling efficiency and sample quality.